FIGURE

Fig. 1

ID

ZDB-FIG-060908-2

Publication

Cheng et al., 2006 - HNF factors form a network to regulate liver-enriched genes in zebrafish

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Fig. 1

Classification of liver-enriched genes in zebrafish. RNA samples were extracted from the dissected liver and liver-free body, respectively. In panel A, RNA samples from 3 dpf embryos were also included. Probes were derived from EST clones or gene fragments cloned in plasmid vector via RT-PCR using gene-specific primers (Table 1; Supplementary Table 4). RNA hybridization blots were arranged according to the descending ratio of expression levels of liver vs. liver-free body (as indicated in the bracket). We arbitrarily grouped this set of genes according to the ratio of expression level. Genes with ratios more than 6.9 are considered as liver-specific genes, ratios between 6.9 and 2 as highly-liver-enriched genes and ratios less than 2 as moderately-liver-enriched genes. Clone identification is shown on the right side. Hybridization intensity was quantified using software Molecular Analyst (Bio-rad). B, liver-free body; L, liver; E, 3 dpf embryos.

Expression Data

Genes:	a1cf acaa1 adh8a agt ahcy ahsg1 aldob ambp apoa2 apoba apoc1 apoc2 apom bckdhbl bhmt c8a c8gl c9 cbln10 cfb chrna5 cp cpn1 cyp2aa6 cyp2ad2 cyp2x12 cyp24a1 dhrs9 dio2 dync1li1 esr1 esr2b f2 fabp10a fads2 fbp1b fetub fga fgg fn1b foxa3 fxyd3 gatm gchfr gdal gpt gstp1.2 hnf4a hpda hpxa igfbp2a itih2 itih3b.2 kng1 ldhbb lipca lpla mat1a med12 mpx msmbl mst1 mycla nots nupr1b olfm1b pklr plg pnp4b proca rbp4 rcn3 rpl5a rps6 sat2a.2 scp2a sdr16c5b serpina1l serpina7 serpinc1 serpind1 serpinf2a serping1 sid4 slc1a3a slc38a4 sox4a tfa tgfbi tprb tpt1 uox vcanb vtg2 vtnb wu:fb58h05 wu:fc26d05 wu:fd55c06 wu:fi15h08 zar1 zgc:123103 zgc:153921
Fish:	WT
Anatomical Terms:	intestine liver pancreas whole organism
Stage Range:	Protruding-mouth to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 294(2), Cheng, W., Guo, L., Zhang, Z., Soo, H.M., Wen, C., Wu, W., and Peng, J., HNF factors form a network to regulate liver-enriched genes in zebrafish, 482-496, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.