Gene

cyp24a1

ID
ZDB-GENE-060825-1
Name
cytochrome P450, family 24, subfamily A, polypeptide 1
Symbol
cyp24a1 Nomenclature History
Previous Names
  • cyp24a1l
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity; 25-hydroxycholecalciferol-24-hydroxylase activity; and vitamin D 25-hydroxylase activity. Predicted to be involved in fatty acid omega-oxidation; response to vitamin D; and vitamin D catabolic process. Is expressed in liver. Human ortholog(s) of this gene implicated in hypercalcemia. Orthologous to human CYP24A1 (cytochrome P450 family 24 subfamily A member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cyp24a1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Hypercalcemia, infantile, 1 143880
Associated With cyp24a1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017972 Cytochrome P450, conserved site
Family IPR001128 Cytochrome P450
Family IPR002401 Cytochrome P450, E-class, group I
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
Domain Details Per Protein
Protein Length Cytochrome P450 Cytochrome P450, conserved site Cytochrome P450, E-class, group I Cytochrome P450 superfamily
UniProtKB:A0A0R4IBW0 505
UniProtKB:A3KNB0 505
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations