Gene
tfa
- ID
- ZDB-GENE-980526-35
- Name
- transferrin-a
- Symbol
- tfa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity. Involved in hemoglobin biosynthetic process; iron ion transport; and response to bacterium. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in several diseases, including atransferrinemia; carcinoma (multiple); glucose metabolism disease (multiple); iron deficiency anemia; and restless legs syndrome. Is expressed in several structures, including ball; liver; ovary; renal system; and yolk syncytial layer. Orthologous to several human genes including TF (transferrin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 52 figures from 36 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb285 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Fraenkel et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| atransferrinemia | Alliance | Atransferrinemia | 209300 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Transferrin | Transferrin family, iron binding site | Transferrin-like domain |
|---|---|---|---|---|
|
UniProtKB:Q6P3G0
|
520 | |||
|
UniProtKB:B8JL43
|
673 |
Interactions and Pathways
No data available
Plasmids
No data available