Gene

tfa

ID
ZDB-GENE-980526-35
Name
transferrin-a
Symbol
tfa Nomenclature History
Previous Names
  • cb285 (1)
  • gavi (1)
  • id:ibd3238
  • id:ibd3525
  • sb:cb285
  • transferrin (1)
  • trf (1)
  • wu:fb57g06
  • wu:fb62h02
  • wu:fb63h10
  • wu:fb64h10
  • zgc:112154
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have metal ion binding activity. Involved in hemoglobin biosynthetic process; iron ion transport; and response to bacterium. Predicted to localize to endosome; extracellular space; and plasma membrane. Is expressed in several structures, including ball; liver; ovary; renal system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including atransferrinemia; carcinoma (multiple); glucose metabolism disease (multiple); iron deficiency anemia; and restless legs syndrome. Orthologous to several human genes including TF (transferrin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
45 figures from 30 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Fraenkel et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tfa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
atransferrinemia Alliance Atransferrinemia 209300
Associated With tfa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018195 Transferrin family, iron binding site
Domain IPR001156 Transferrin-like domain
Family IPR016357 Transferrin
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations