Gene

apoc2

ID
ZDB-GENE-030131-2168
Name
apolipoprotein C-II
Symbol
apoc2 Nomenclature History
Previous Names
  • fb71a04
  • fb98g08
  • wu:fb52e03
  • wu:fb71a04
  • wu:fb98g08
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to enable enzyme activator activity. Acts upstream of or within definitive hemopoiesis and lipoprotein catabolic process. Predicted to be located in extracellular region. Predicted to be part of several cellular components, including chylomicron; low-density lipoprotein particle; and very-low-density lipoprotein particle. Is expressed in intestine; liver; pancreas; and yolk. Used to study familial hyperlipidemia; familial lipoprotein lipase deficiency; and hyperlipoproteinemia type IV. Human ortholog(s) of this gene implicated in familial apolipoprotein C-II deficiency; familial hyperlipidemia; and multiple sclerosis. Orthologous to human APOC2 (apolipoprotein C2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
19 figures from 6 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With apoc2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial apolipoprotein C-II deficiency Alliance Hyperlipoproteinemia, type Ib 207750
Associated With apoc2 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR008019 Apolipoprotein C-II
Homologous_superfamily IPR023121 ApoC-II domain superfamily
Domain Details Per Protein
Protein Length ApoC-II domain superfamily Apolipoprotein C-II
UniProtKB:E9QEQ1 100
UniProtKB:A0A286YAE3 114
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations