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Gene

rbp4

ID
ZDB-GENE-000210-19
Name
retinol binding protein 4, plasma
Symbol
rbp4 Nomenclature History
Previous Names
  • rbp
  • fb23c12
  • wu:fb23c12
  • wu:fb58d04 (1)
  • wu:fb72b04 (1)
  • zgc:86911
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to enable retinol binding activity. Acts upstream of or within liver development and response to retinoic acid. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including apical ectodermal ridge; digestive system; integument; reproductive system; and yolk. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human RBP4 (retinol binding protein 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
23 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Li et al., 2007
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rbp4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Microphthalmia, isolated, with coloboma 10 616428
Retinal dystrophy, iris coloboma, and comedogenic acne syndrome 615147
Associated With rbp4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR022272 Lipocalin family conserved site
Domain IPR000566 Lipocalin/cytosolic fatty-acid binding domain
Family IPR002449 Retinol binding protein/Purpurin
Family IPR022271 Lipocalin, ApoD type
Homologous_superfamily IPR012674 Calycin
Domain Details Per Protein
Protein Length Calycin Lipocalin, ApoD type Lipocalin/cytosolic fatty-acid binding domain Lipocalin family conserved site Retinol binding protein/Purpurin
UniProtKB:A0A0R4IVC3 169
UniProtKB:Q9PT95 192
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations