ZFIN ID: ZDB-GENE-000210-19
Gene Name: retinol binding protein 4, plasma
Gene Symbol: rbp4
Sequence Ontology ID : SO:0000704

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Previous Names: rbp, fb23c12, wu:fb23c12, wu:fb58d04 (1), wu:fb72b04 (1), zgc:86911

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have retinoid binding activity and retinol transmembrane transporter activity; involved in liver development and response to retinoic acid; orthologous to human RBP4 (retinol binding  ...
GENE EXPRESSION
All Expression Data: 22 figures from 9 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu673]
  6 figures (7 images) from Thisse et al., 2005 [eu787]
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa35200 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 3 figures from Li et al., 2007
    Observed in:
    DISEASE ASSOCIATED WITH rbp4 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Microphthalmia, isolated, with coloboma 10 616428
    Retinal dystrophy, iris coloboma, and comedogenic acne syndrome 615147
    DISEASE ASSOCIATED WITH rbp4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to retinoic acid (more)
    Molecular Function retinoid binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000566 (1)
  • InterPro:IPR002449 (1)
  • InterPro:IPR012674 (1)
  • InterPro:IPR022271 (1)
  • InterPro:IPR022272 (1)
  • PROSITE:PS00213 (1)
  • Pfam:PF00061 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA rbp4-001 (1) 1044
    rbp4-002 (1) 574
    ncRNA rbp4-003 (1) 850
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM rbp4 No data available
    MARKER RELATIONSHIPS
    rbp4Contained in: [BAC] CH211-149K17 (1) (order this)
    rbp4Encodes: [EST] eu673 (1), eu787 (1), fb23c12, fb58d04 (1), fb72b04 (1)
    [cDNA] MGC:86911 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130920 (1) 1032bp
    Genomic GenBank:AL929469 (1) 146415bp
    Select Tool
    Polypeptide UniProtKB:Q9PT95 (1) 192aa
    Sequence Clusters UniGene:1400 (1)
    Sequence Information (all 27)
    OTHER rbp4 GENE PAGES
  • Alliance (1)
  • Gene:30077 (1)
  • VEGA:OTTDARG00000020492 (1)
  • Ensembl(GRCz11):ENSDARG00000101199 (1)
  • ORTHOLOGY for rbp4 (Chr: 12)
    CITATIONS (44)