Gene

mpx

ID
ZDB-GENE-030131-9460
Name
myeloid-specific peroxidase
Symbol
mpx Nomenclature History
Previous Names
  • drf
  • fj80f04
  • mpo (1)
  • myeloperoxidase (1)
  • unm t30963
  • unm_sm681
  • unm_t30963
  • wu:fj80f04
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Exhibits peroxidase activity. Involved in inflammatory response; regulation of hydrogen peroxide metabolic process; and response to bacterium. Localizes to cytoplasm. Is expressed in several structures, including hematopoietic cell; hematopoietic system; mesoderm; pleuroperitoneal region; and post-vent region.
Genome Resources
Note
None
Expression
All Expression Data
286 figures from 194 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mpx Human Ortholog
No data available
Associated With mpx Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001073 C1q domain
Family IPR019791 Haem peroxidase, animal-type
Family IPR029599 Eosinophil peroxidase
Homologous_superfamily IPR008983 Tumour necrosis factor-like domain superfamily
Homologous_superfamily IPR010255 Haem peroxidase superfamily
Homologous_superfamily IPR037120 Haem peroxidase domain superfamily, animal type
Domain Details Per Protein
Protein Length C1q domain Eosinophil peroxidase Haem peroxidase, animal-type Haem peroxidase domain superfamily, animal type Haem peroxidase superfamily Tumour necrosis factor-like domain superfamily
UniProtKB:Q90WB2 254
UniProtKB:Q7SZR3 893
UniProtKB:Q90WB3 350
UniProtKB:Q90Z78 127
UniProtKB:Q90WB4 678
UniProtKB:F1R9R1 893
UniProtKB:Q90XS6 762
UniProtKB:Q6NUY7 893
UniProtKB:F1Q944 762
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab5-mpx polyclonal IgG Rabbit
  • IHC
GeneTex
6
Ab1-mpx polyclonal Rabbit
  • IHC
8
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations