ZFIN ID: ZDB-GENE-030131-9460
Gene Name: myeloid-specific peroxidase
Gene Symbol: mpx
Sequence Ontology ID : SO:0000704

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Previous Names: drf, fj80f04, mpo (1), myeloperoxidase (1), unm t30963, unm_sm681, unm_t30963, wu:fj80f04

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits peroxidase activity; involved in inflammatory response, regulation of hydrogen peroxide metabolic process, and response to bacterium; localizes to the cytoplasm; orthologous to several human  ...
GENE EXPRESSION
All Expression Data: 253 figures from 175 publications
Directly Submitted Expression Data: 3 figures (3 images) from Thisse et al., 2001 [cb1013]
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
gl8 Point Mutation Unknown Unknown
sa18566 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21652 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34835 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sm681 Small Deletion Exon 13 Premature Stop ENU
    t30963 Unknown Unknown Unknown ENU
    PHENOTYPE
    Data: 6 figures from 4 publications
    Observed in:
    DISEASE ASSOCIATED WITH mpx HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mpx VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to bacterium (more)
    Cellular Component cytoplasm (more)
    Molecular Function peroxidase activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001073 (1)
  • InterPro:IPR008983 (1)
  • InterPro:IPR010255 (1)
  • InterPro:IPR019791 (1)
  • InterPro:IPR029599 (1)
  • InterPro:IPR037120 (1)
  • PROSITE:PS50292 (1)
  • PROSITE:PS50871 (1)
  • Pfam:PF00386 (1)
  • Pfam:PF03098 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA mpx-003 (1) 1481
    mRNA mpx-201 (1) 3146
    mpx-202 (1) 3199
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mpx
    MARKER RELATIONSHIPS
    mpxContained in: [BAC] CH73-340N8 (1) (order this)
    mpxEncodes: [EST] cb1013 (order this), fj80f04
    [cDNA] MGC:65945 (1) (order this), MGC:85760 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212779 (1) 3846bp
    Genomic GenBank:CU681843 (1) 72220bp
    Select Tool
    Polypeptide UniProtKB:F1R9R1 (1) 893aa
    Sequence Clusters UniGene:75725 (1)
    Sequence Information (all 38)
    OTHER mpx GENE PAGES
  • Alliance (1)
  • Gene:337514 (1)
  • VEGA:OTTDARG00000030890 (1)
  • Ensembl(GRCz11):ENSDARG00000019521 (2)
  • ORTHOLOGY for mpx (Chr: 10)
    CITATIONS (358)