Gene

foxa3

ID
ZDB-GENE-980526-423
Name
forkhead box A3
Symbol
foxa3 Nomenclature History
Previous Names
  • fa11c04
  • fc37a08
  • fkd2 (1)
  • forkhead-2
  • wu:fa11c04
  • wu:fc37a08
  • zf-FKH1
  • Zffkh1
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including axial mesoderm morphogenesis; hatching gland development; and nervous system development. Localizes to nucleus. Is expressed in several structures, including axial mesoderm; digestive system; endoderm; germ ring; and hatching gland. Orthologous to human FOXA3 (forkhead box A3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
166 figures from 138 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With foxa3 Human Ortholog
No data available
Associated With foxa3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018122 Fork head domain conserved site1
Conserved_site IPR030456 Fork head domain conserved site 2
Domain IPR001766 Fork head domain
Domain IPR013638 Fork-head N-terminal
Domain IPR018533 Forkhead box protein, C-terminal
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Forkhead box protein, C-terminal Fork head domain Fork head domain conserved site1 Fork head domain conserved site 2 Fork-head N-terminal Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:O73778 441
UniProtKB:B3DGF9 441
UniProtKB:Q1LV18 441
UniProtKB:Q4VNS3 75
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-foxa3 polyclonal Rabbit
  • IHC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations