Gene

apoba

ID
ZDB-GENE-070702-4
Name
apolipoprotein Ba
Symbol
apoba Nomenclature History
Previous Names
  • apob (1)
  • im:6911942
  • wu:fb30e06
  • zmp:0000000614 (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have lipid transporter activity. Predicted to be involved in cholesterol transport and triglyceride mobilization. Predicted to localize to endoplasmic reticulum. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); biliary tract cancer (multiple); familial hyperlipidemia (multiple); hypobetalipoproteinemia (multiple); and sickle cell anemia. Is expressed in heart; liver; and yolk syncytial layer. Orthologous to human APOB (apolipoprotein B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
15 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With apoba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial hypobetalipoproteinemia 1 Alliance Hypobetalipoproteinemia 615558
Hypercholesterolemia, familial, 2 144010
Associated With apoba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001747 Vitellogenin, N-terminal
Domain IPR009454 Lipid transport, open beta-sheet
Domain IPR015255 Vitellinogen, open beta-sheet
Homologous_superfamily IPR011030 Lipovitellin-phosvitin complex, superhelical domain
Homologous_superfamily IPR015816 Vitellinogen, beta-sheet N-terminal
Homologous_superfamily IPR015819 Lipid transport protein, beta-sheet shell
Domain Details Per Protein
Protein Length Lipid transport, open beta-sheet Lipid transport protein, beta-sheet shell Lipovitellin-phosvitin complex, superhelical domain Vitellinogen, beta-sheet N-terminal Vitellinogen, open beta-sheet Vitellogenin, N-terminal
UniProtKB:E7FBD3 4418
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations