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General Information
ZIRC
ZFIN ID: ZDB-GENE-010907-1
Gene Name: pyruvate kinase L/R
Gene Symbol: pklr
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: wu:fd15e01, wu:fi37e08

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have kinase activity; metal ion binding activity; and pyruvate kinase activity. Involved in liver development. Human ortholog(s) of this gene implicated in Gaucher's disease; congenital  ...
GENE EXPRESSION
All Expression Data: 13 figures from 9 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pklr HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
pyruvate kinase deficiency of red cells Pyruvate kinase deficiency 266200
Adenosine triphosphate, elevated, of erythrocytes 102900
DISEASE ASSOCIATED WITH pklr VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process liver development (more)
Molecular Function catalytic activity (more)
GO Terms (all 9)
TRANSCRIPTS No data available
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM pklr No data available
MARKER RELATIONSHIPS
pklrEncodes: [EST] fd15e01 (1), fi37e08 (1)
[cDNA] MGC:66245 (1) (order this), MGC:174509 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_201289 (1) 1807bp
Polypeptide UniProtKB:A8KC20 (1) 538aa
Sequence Clusters UniGene:77543 (1)
Sequence Information (all 26)
OTHER pklr GENE PAGES
  • Alliance (1)
  • Gene:114551 (1)
  • Ensembl(GRCz11):ENSDARG00000042010 (2)
  • ORTHOLOGY for pklr (Chr: 16)
    CITATIONS (48)