Gene
cp
- ID
- ZDB-GENE-010522-1
- Name
- ceruloplasmin
- Symbol
- cp Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have ferroxidase activity. Predicted to be involved in iron ion homeostasis and iron ion transport. Localizes to cytoplasm and nucleus. Is expressed in digestive system; female organism; liver and biliary system; male organism; and yolk syncytial layer. Human ortholog(s) of this gene implicated in aceruloplasminemia; epilepsy; and hemosiderosis. Orthologous to human CP (ceruloplasmin).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 95 figures from 61 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55445 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Choksi et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
aceruloplasminemia | Alliance | Aceruloplasminemia | 604290 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Binding_site | IPR002355 | Multicopper oxidase, copper-binding site |
Conserved_site | IPR033138 | Multicopper oxidases, conserved site |
Domain | IPR011706 | Multicopper oxidase, C-terminal |
Domain | IPR011707 | Multicopper oxidase-like, N-terminal |
Domain | IPR048236 | Ceruloplasmin-like, fifth cupredoxin domain |
Family | IPR050633 | Neuropilin/Multicopper Oxidase/Coagulation Factor |
Homologous_superfamily | IPR008972 | Cupredoxin |
Domain Details Per Protein
Protein | Length | Ceruloplasmin-like, fifth cupredoxin domain | Cupredoxin | Multicopper oxidase, copper-binding site | Multicopper oxidase, C-terminal | Multicopper oxidase-like, N-terminal | Multicopper oxidases, conserved site | Neuropilin/Multicopper Oxidase/Coagulation Factor |
---|---|---|---|---|---|---|---|---|
UniProtKB:Q7ZU12
|
1087 |
Interactions and Pathways
No data available
Plasmids
No data available