Gene

cp

ID
ZDB-GENE-010522-1
Name
ceruloplasmin
Symbol
cp Nomenclature History
Previous Names
  • cer (1)
  • wu:fi23f10 (1)
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have ferroxidase activity. Predicted to be involved in iron ion homeostasis and iron ion transport. Localizes to cytoplasm and nucleus. Is expressed in digestive system; female organism; liver and biliary system; male organism; and yolk syncytial layer. Human ortholog(s) of this gene implicated in aceruloplasminemia; epilepsy; and hemosiderosis. Orthologous to human CP (ceruloplasmin).
Genome Resources
Note
None
Expression
All Expression Data
83 figures from 52 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. 3 from Choksi et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cp Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
aceruloplasminemia Alliance Cerebellar ataxia 604290
aceruloplasminemia Alliance Hemosiderosis, systemic, due to aceruloplasminemia 604290
aceruloplasminemia Alliance [Hypoceruloplasminemia, hereditary] 604290
Associated With cp Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR002355 Multicopper oxidase, copper-binding site
Conserved_site IPR033138 Multicopper oxidases, conserved site
Domain IPR011706 Multicopper oxidase, type 2
Domain IPR011707 Multicopper oxidase, type 3
Homologous_superfamily IPR008972 Cupredoxin
Domain Details Per Protein
Protein Length Cupredoxin Multicopper oxidase, copper-binding site Multicopper oxidases, conserved site Multicopper oxidase, type 2 Multicopper oxidase, type 3
UniProtKB:Q7ZU12 1087
UniProtKB:F1RBQ0 193
UniProtKB:F1Q8N4 194
UniProtKB:Q6P3G1 1087
UniProtKB:Q90ZT2 626
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cp polyclonal Rabbit
  • WB
AnaSpec
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations