Gene
cpn1
- ID
- ZDB-GENE-030131-9116
- Name
- carboxypeptidase N, polypeptide 1
- Symbol
- cpn1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have metallocarboxypeptidase activity. Involved in cellular response to estrogen stimulus; liver development; and sprouting angiogenesis. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in carboxypeptidase N deficiency. Is expressed in several structures, including digestive system; mesoderm; nervous system; pectoral fin cartilage; and vasculature. Orthologous to human CPN1 (carboxypeptidase N subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1037 (23 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Wu et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| carboxypeptidase N deficiency | Alliance | Carboxypeptidase N deficiency | 212070 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Carboxypeptidase-like, regulatory domain superfamily | Peptidase M14, carboxypeptidase A | Peptidase M14 domain-containing protein |
|---|---|---|---|---|
|
UniProtKB:Q6NY94
|
450 |
Interactions and Pathways
No data available
Plasmids
No data available