Gene
gatm
- ID
- ZDB-GENE-021015-1
- Name
- glycine amidinotransferase (L-arginine:glycine amidinotransferase)
- Symbol
- gatm Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Is predicted to enable glycine amidinotransferase activity. Involved in creatine biosynthetic process. Predicted to be located in mitochondrial inner membrane. Is expressed in several structures, including digestive system; mesoderm; musculature system; ovary; and yolk syncytial layer. Human ortholog(s) of this gene implicated in AGAT deficiency and Fanconi renotubular syndrome 1. Orthologous to human GATM (glycine amidinotransferase).
- Genome Resources
- Note
-
Added for the Thisse expression data.
- Comparative Information
-
- All Expression Data
- 11 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb409 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| AGAT deficiency | Alliance | Cerebral creatine deficiency syndrome 3 | 612718 |
| Fanconi renotubular syndrome 1 | Alliance | Fanconi renotubular syndrome 1 | 134600 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR033195 | Glycine/inosamine-phosphate amidinotransferase |
Domain Details Per Protein
| Protein | Length | Glycine/inosamine-phosphate amidinotransferase |
|---|---|---|
|
UniProtKB:Q6PH19
|
422 |
Interactions and Pathways
No data available
Plasmids
No data available