Gene
gstp1.2
- ID
- ZDB-GENE-020806-4
- Name
- glutathione S-transferase pi 1.2
- Symbol
- gstp1.2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Exhibits glutathione transferase activity. Involved in cellular response to xenobiotic stimulus. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in several diseases, including brain disease (multiple); carcinoma (multiple); hematologic cancer (multiple); neurodegenerative disease (multiple); and respiratory system disease (multiple). Is expressed in several structures, including digestive system; endoderm; nervous system; pleuroperitoneal region; and yolk syncytial layer. Orthologous to human GSTP1 (glutathione S-transferase pi 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 59 figures from 38 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb356 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Zhang et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004045 | Glutathione S-transferase, N-terminal |
| Domain | IPR004046 | Glutathione S-transferase, C-terminal |
| Domain | IPR010987 | Glutathione S-transferase, C-terminal-like |
| Family | IPR003082 | Glutathione S-transferase, Pi class |
| Family | IPR040079 | Glutathione transferase family |
| Family | IPR050213 | Glutathione S-transferase superfamily |
| Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
| Homologous_superfamily | IPR036282 | Glutathione S-transferase, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Glutathione S-transferase, C-terminal | Glutathione S-transferase, C-terminal domain superfamily | Glutathione S-transferase, C-terminal-like | Glutathione S-transferase, N-terminal | Glutathione S-transferase, Pi class | Glutathione S-transferase superfamily | Glutathione transferase family | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9DDU5
|
208 |
Interactions and Pathways
No data available
Plasmids
No data available