Gene
aldob
- ID
- ZDB-GENE-030131-383
- Name
- aldolase b, fructose-bisphosphate
- Symbol
- aldob Nomenclature History
- Previous Names
-
- fb25f09
- wu:fb25f09
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have fructose-1-phosphate aldolase activity and fructose-bisphosphate aldolase activity. Predicted to be involved in fructose 1,6-bisphosphate metabolic process and glycolytic process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in hereditary fructose intolerance syndrome and type 2 diabetes mellitus. Is expressed in several structures, including EVL; alar plate midbrain region; digestive system; intestinal bulb primordium; and midbrain. Orthologous to human ALDOB (aldolase, fructose-bisphosphate B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 31 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77642 (13 images)
- IMAGE:7154212 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary fructose intolerance syndrome | Alliance | Fructose intolerance, hereditary | 229600 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Aldolase-type TIM barrel | Fructose-bisphosphate aldolase, class-I | Fructose-bisphosphate aldolase class-I active site |
|---|---|---|---|---|
|
UniProtKB:Q8JH71
|
364 |
Interactions and Pathways
No data available
Plasmids
No data available