Gene

fn1b

ID
ZDB-GENE-030131-6545
Name
fibronectin 1b
Symbol
fn1b Nomenclature History
Previous Names
  • fn1l
  • fn3 (1)
  • cb1057 (1)
  • wu:fa14f11
  • wu:fb03c02
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable integrin binding activity and proteoglycan binding activity. Acts upstream of or within atrioventricular valve morphogenesis; heart field specification; and somitogenesis. Predicted to be located in extracellular region. Is expressed in several structures, including fin; heart; integument; mesoderm; and musculature system. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis; membranoproliferative glomerulonephritis; and spondylometaphyseal dysplasia corner fracture type. Orthologous to human FN1 (fibronectin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
37 figures from 20 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Steed et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fn1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spondylometaphyseal dysplasia corner fracture type Alliance Spondylometaphyseal dysplasia, corner fracture type 184255
Glomerulopathy with fibronectin deposits 2 601894
Associated With fn1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000083 Fibronectin, type I
Domain IPR000562 Fibronectin type II domain
Domain IPR003961 Fibronectin type III
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR013806 Kringle-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Homologous_superfamily IPR036943 Fibronectin type II domain superfamily
Domain Details Per Protein
Protein Length Fibronectin, type I Fibronectin type II domain Fibronectin type II domain superfamily Fibronectin type III Fibronectin type III superfamily Immunoglobulin-like fold Kringle-like fold
UniProtKB:Q6JAN2 2408
UniProtKB:A0A8M2B744 2407
UniProtKB:A2CEW3 2500
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations