Gene

fn1b

ID
ZDB-GENE-030131-6545
Name
fibronectin 1b
Symbol
fn1b Nomenclature History
Previous Names
  • fn1l
  • fn3 (1)
  • cb1057 (1)
  • wu:fa14f11
  • wu:fb03c02
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable integrin binding activity and proteoglycan binding activity. Acts upstream of or within atrioventricular valve morphogenesis; heart field specification; and somitogenesis. Predicted to be located in extracellular space. Is expressed in several structures, including fin; heart; integument; mesoderm; and musculature system. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis; membranoproliferative glomerulonephritis; and spondylometaphyseal dysplasia corner fracture type. Orthologous to human FN1 (fibronectin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
44 figures from 26 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Steed et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fn1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spondylometaphyseal dysplasia corner fracture type Alliance Spondylometaphyseal dysplasia, corner fracture type 184255
Glomerulopathy with fibronectin deposits 2 601894
1 - 2 of 2
Associated With fn1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000083 Fibronectin, type I
Domain IPR000562 Fibronectin type II domain
Domain IPR003961 Fibronectin type III
Family IPR050991 Extracellular Matrix Regulatory Proteins
Homologous_superfamily IPR013783 Immunoglobulin-like fold
1 - 5 of 8 Show all
Domain Details Per Protein
Protein Additional Resources Length Extracellular Matrix Regulatory Proteins Fibronectin, type I Fibronectin type II domain Fibronectin type II domain superfamily Fibronectin type III Fibronectin type III superfamily Immunoglobulin-like fold Kringle-like fold
UniProtKB:Q6JAN2 InterPro 2408
UniProtKB:A0A8M2B744 InterPro 2407
UniProtKB:A2CEW3 InterPro 2500
1 - 3 of 3
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA fn1b-201 (1)
Ensembl
Ensembl 1,212 nt
ZFIN BLAST
mRNA fn1b-202 (1)
Ensembl
Ensembl 8,522 nt
ZFIN BLAST
mRNA fn1b-205 (1)
Ensembl
Ensembl 8,191 nt
ZFIN BLAST
ncRNA fn1b-004 (1)
Ensembl
Ensembl 959 nt
ZFIN BLAST
ncRNA fn1b-005 (1)
Ensembl
Ensembl 656 nt
ZFIN BLAST
1 - 5 of 5
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
Your Input Welcome
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