Gene
tgfbi
- ID
- ZDB-GENE-030131-73
- Name
- transforming growth factor, beta-induced
- Symbol
- tgfbi Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable cell adhesion molecule binding activity. Acts upstream of or within cellular response to xenobiotic stimulus and muscle cell development. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. Is expressed in several structures, including head mesenchyme; liver; neural crest cell; paraxial mesoderm; and splanchnocranium. Human ortholog(s) of this gene implicated in corneal dystrophy (multiple). Orthologous to human TGFBI (transforming growth factor beta induced).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 25 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6903641 (23 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Kim et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
epithelial basement membrane dystrophy | Alliance | Corneal dystrophy, epithelial basement membrane | 121820 |
granular corneal dystrophy 1 | Alliance | Corneal dystrophy, Groenouw type I | 121900 |
granular corneal dystrophy 2 | Alliance | Corneal dystrophy, Avellino type | 607541 |
lattice corneal dystrophy | Alliance | Corneal dystrophy, lattice type I | 122200 |
Reis-Bucklers corneal dystrophy | Alliance | Corneal dystrophy, Reis-Bucklers type | 608470 |
Thiel-Behnke corneal dystrophy | Alliance | Corneal dystrophy, Thiel-Behnke type | 602082 |
Corneal dystrophy, lattice type IIIA | 608471 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Cell adhesion and biosynthesis-related protein | EMI domain | FAS1 domain | FAS1 domain superfamily | TGF beta-induced protein/periostin |
---|---|---|---|---|---|---|
UniProtKB:Q7T1R2
|
677 |
Interactions and Pathways
No data available
Plasmids
No data available