Gene

vcanb

ID
ZDB-GENE-030131-2185
Name
versican b
Symbol
vcanb Nomenclature History
Previous Names
  • cspg2b (1)
  • dermacan (1)
  • fb99b07
  • wu:fb99b07
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity and hyaluronic acid binding activity. Involved in intramembranous ossification and skeletal system development. Predicted to localize to extracellular matrix. Is expressed in several structures, including dermatocranium; otic vesicle; paraxial mesoderm; semicircular canal; and ventral fin fold. Human ortholog(s) of this gene implicated in intracranial aneurysm. Orthologous to human VCAN (versican).
Genome Resources
Note
None
Expression
All Expression Data
13 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vcanb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Wagner syndrome 1 143200
Associated With vcanb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
Conserved_site IPR013032 EGF-like, conserved site
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Conserved_site IPR018378 C-type lectin, conserved site
Domain IPR000436 Sushi/SCR/CCP domain
Domain IPR000538 Link domain
Domain IPR000742 EGF-like domain
Domain IPR001304 C-type lectin-like
Domain IPR001881 EGF-like calcium-binding domain
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013106 Immunoglobulin V-set domain
Domain IPR033987 Aggrecan/versican, C-type lectin-like domain
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR016186 C-type lectin-like/link domain superfamily
Homologous_superfamily IPR016187 C-type lectin fold
Homologous_superfamily IPR035976 Sushi/SCR/CCP superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Domain Details Per Protein
Protein Length Aggrecan/versican, C-type lectin-like domain C-type lectin, conserved site C-type lectin fold C-type lectin-like C-type lectin-like/link domain superfamily EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like, conserved site EGF-like domain EGF-type aspartate/asparagine hydroxylation site Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin/major histocompatibility complex, conserved site Immunoglobulin subtype Immunoglobulin V-set domain Link domain Sushi/SCR/CCP domain Sushi/SCR/CCP superfamily
UniProtKB:Q75ZI3 1570
UniProtKB:A0A2R8QK78 1570
UniProtKB:F1QFM9 1569
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations