Gene

fads2

ID
ZDB-GENE-011212-1
Name
fatty acid desaturase 2
Symbol
fads2 Nomenclature History
Previous Names
  • Fadsd6 (1)
  • DRD5/D6 (1)
  • wu:fb64c04
  • wu:fb69e08
  • zgc:112502
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water. Acts upstream of or within liver development. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alar plate midbrain region; fat cell; nervous system; optic vesicle; and pleuroperitoneal region. Orthologous to several human genes including FADS2 (fatty acid desaturase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
24 figures from 15 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fads2 Human Ortholog
No data available
Associated With fads2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001199 Cytochrome b5-like heme/steroid binding domain
Domain IPR005804 Fatty acid desaturase domain
Family IPR012171 Fatty acid desaturase
Homologous_superfamily IPR036400 Cytochrome b5-like heme/steroid binding domain superfamily
Domain Details Per Protein
Protein Length Cytochrome b5-like heme/steroid binding domain Cytochrome b5-like heme/steroid binding domain superfamily Fatty acid desaturase Fatty acid desaturase domain
UniProtKB:A9JSU3
UniProtKB:F6NP64 421
UniProtKB:F1R3G9 444
UniProtKB:A8E549 158
UniProtKB:Q9DEX7 444
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations