Gene
rpl5a
- ID
- ZDB-GENE-030131-5161
- Name
- ribosomal protein L5a
- Symbol
- rpl5a Nomenclature History
- Previous Names
-
- rpl5l
- mg:cb01f08
- zgc:77176
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable 5S rRNA binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within chordate embryonic development. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in intestine; liver; and pancreas. Used to study Diamond-Blackfan anemia. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 6; T-cell acute lymphoblastic leukemia; and glioblastoma. Orthologous to human RPL5 (ribosomal protein L5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6909214 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Diamond-Blackfan anemia 6 | Alliance | Diamond-Blackfan anemia 6 | 612561 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Diamond-Blackfan anemia | AB + MO1-rpl5a | standard conditions | Wan et al., 2016 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Large ribosomal subunit protein uL18, C-terminal, eukaryotes | Large ribosomal subunit protein uL18 eukaryotic/archaeal |
|---|---|---|---|
|
UniProtKB:Q7ZUI0
|
297 |
Interactions and Pathways
No data available
Plasmids
No data available