ZFIN

ZFIN ID: ZDB-GENE-980526-321

ZFIN ID: ZDB-GENE-980526-321

CITATIONS (372 total)

Gene Name:	NK2 homeobox 5
Gene Symbol:	nkx2.5

DeMoya, R.A., Forman-Rubinsky, R.E., Fontaine, D., Shin, J., Watkins, S.C., Lo, C.W., Tsang, M. (2023) Sin3a associated protein 130 kDa, sap130, plays an evolutionary conserved role in zebrafish heart development. Frontiers in cell and developmental biology. 11:11971091197109

Martin, K.E., Ravisankar, P., Beerens, M., MacRae, C.A., Waxman, J.S. (2023) Nr2f1a maintains atrial nkx2.5 expression to repress pacemaker identity within venous atrial cardiomyocytes of zebrafish. eLIFE. 12:

Kent, M.E., Hu, B., Eggleston, T.M., Squires, R.S., Zimmerman, K.A., Weiss, R.M., Roghair, R.D., Lin, F., Cornell, R.A., Haskell, S.E. (2022) Hypersensitivity of zebrafish htr2b mutant embryos to sertraline indicates a role for serotonin signaling in cardiac development. Journal of Cardiovascular Pharmacology. 80(2):261-269

Ouyang, S., Qin, W.M., Niu, Y.J., Ding, Y.H., Deng, Y. (2022) An EGFP Knock-in Zebrafish Experimental Model Used in Evaluation of the Amantadine Drug Safety During Early Cardiogenesis. Frontiers in cardiovascular medicine. 9:839166

Wang, Y.Y., Nie, L., Xu, X.X., Shao, T., Fan, D.D., Lin, A.F., Xiang, L.X., Shao, J.Z. (2022) Essential Role of RIG-I in Hematopoietic Precursor Emergence in Primitive Hematopoiesis during Zebrafish Development. ImmunoHorizons. 6:283-298

Chen, X., Li, W. (2021) Isoflucypram cardiovascular toxicity in zebrafish (Danio rerio). The Science of the total environment. 787:147529

Fan, E., Xu, Z., Yan, J., Wang, F., Sun, S., Zhang, Y., Zheng, S., Wang, X., Rao, Y. (2021) Acute exposure to N-Ethylpentylone induces developmental toxicity and dopaminergic receptor-regulated aberrances in zebrafish larvae. Toxicology and applied pharmacology. 417:115477

He, L., Zhang, Q., Jiang, D., Zhang, Y., Wei, Y., Yang, Y., Li, N., Wang, S., Yue, Y., Zhao, Q. (2021) Zebrafish foxc1a controls ventricular chamber maturation by directly regulating wwtr1 and nkx2.5 expression. Journal of genetics and genomics = Yi chuan xue bao. 49(6):559-568

Jing, Y., Ren, Y., Witzel, H.R., Dobreva, G. (2021) A BMP4-p38 MAPK signaling axis controls ISL1 protein stability and activity during cardiogenesis. Stem Cell Reports. 16(8):1894-1905

Ma, J., Huang, Y., Jiang, P., Liu, Z., Luo, Q., Zhong, K., Yuan, W., Meng, Y., Lu, H. (2021) Pyridaben induced cardiotoxicity during the looping stages of zebrafish (Danio rerio) embryos. Aquatic toxicology (Amsterdam, Netherlands). 237:105870

Ma, J., Huang, Y., Peng, Y., Xu, Z., Wang, Z., Chen, X., Xie, S., Jiang, P., Zhong, K., Lu, H. (2021) Bifenazate exposure induces cardiotoxicity in zebrafish embryos. Environmental pollution (Barking, Essex : 1987). 274:116539

Meng, Y., Zhong, K., Chen, S., Huang, Y., Wei, Y., Wu, J., Liu, J., Xu, Z., Guo, J., Liu, F., Lu, H. (2021) Cardiac toxicity assessment of pendimethalin in zebrafish embryos. Ecotoxicology and environmental safety. 222:112514

Miklas, J.W., Levy, S., Hofsteen, P., Mex, D.I., Clark, E., Muster, J., Robitaille, A.M., Sivaram, G., Abell, L., Goodson, J.M., Pranoto, I., Madan, A., Chin, M.T., Tian, R., Murry, C.E., Moon, R.T., Wang, Y., Ruohola-Baker, H. (2021) Amino acid primed mTOR activity is essential for heart regeneration. iScience. 25:103574

Peng, Y., Wang, W., Fang, Y., Hu, H., Chang, N., Pang, M., Hu, Y.F., Li, X., Long, H., Xiong, J.W., Zhang, R. (2021) Inhibition of TGF-β/Smad3 Signaling Disrupts Cardiomyocyte Cell Cycle Progression and Epithelial-Mesenchymal Transition-Like Response During Ventricle Regeneration. Frontiers in cell and developmental biology. 9:632372

Ren, Q., Gao, D., Mou, L., Zhang, S., Zhang, M., Li, N., Sik, A., Jin, M., Liu, K. (2021) Anticonvulsant activity of melatonin and its success in ameliorating epileptic comorbidity-like symptoms in zebrafish. European Journal of Pharmacology. 912:174589

Takashima, S., Takemoto, S., Toyoshi, K., Ohba, A., Shimozawa, N. (2021) Zebrafish model of human Zellweger syndrome reveals organ-specific accumulation of distinct fatty acid species and widespread gene expression changes. Molecular genetics and metabolism. 133(3):307-323

Wang, W., Hu, Y.F., Pang, M., Chang, N., Yu, C., Li, Q., Xiong, J.W., Peng, Y., Zhang, R. (2021) BMP and Notch Signaling Pathways differentially regulate Cardiomyocyte Proliferation during Ventricle Regeneration. International journal of biological sciences. 17:2157-2166

Zheng, N., Yan, J., Qian, W., Song, C., Zuo, Z., He, C. (2021) Comparison of developmental toxicity of different surface modified CdSe/ZnS QDs in zebrafish embryos. Journal of environmental sciences (China). 100:240-249

Bautista, N.M., Crespel, A., Crossley, J., Padilla, P., Burggren, W. (2020) Parental transgenerational epigenetic inheritance related to dietary crude oil exposure in Danio rerio. The Journal of experimental biology. 223(Pt 16):

Budine, T.E., de Sena-Tomás, C., Williams, M.L.K., Sepich, D.S., Targoff, K.L., Solnica-Kreze, L. (2020) Gon4l/Udu Regulates Cardiomyocyte Proliferation and Maintenance of Ventricular Chamber Identity During Zebrafish Development. Developmental Biology. 462(2):223-234

Chai, T., Cui, F., Di, S., Wu, S., Zhang, Y., Wang, X. (2020) New insights into cardiotoxicity induced by chiral fluoxetine at environmental-level: Enantioselective arrhythmia in developmental zebrafish (Danio rerio). Environmental pollution (Barking, Essex : 1987). 270:116182

Chu, L., Yin, H., Gao, L., Gao, L., Xia, Y., Zhang, C., Chen, Y., Liu, T., Huang, J., Boheler, K.R., Zhou, Y., Yang, H.T. (2020) Cardiac Na⁺-Ca²⁺ exchanger 1 (ncx1h) is critical for the ventricular cardiomyocyte formation via regulating the expression levels of gata4 and hand2 in zebrafish. Science China. Life sciences. 64(2):255-268

Gou, D., Zhou, J., Song, Q., Wang, Z., Bai, X., Zhang, Y., Zuo, M., Wang, F., Chen, A., Yousaf, M., Yang, Z., Peng, H., Li, K., Xie, W., Tang, J., Yao, Y., Han, M., Ke, T., Chen, Q., Xu, C., Wang, Q. (2020) Mog1 knockout causes cardiac hypertrophy and heart failure by downregulating tbx5-cryab-hspb2 signaling in zebrafish. Acta physiologica (Oxford, England). 231(3):e13567

Gu, J., Wang, H., Zhou, L., Fan, D., Shi, L., Ji, G., Gu, A. (2020) Oxidative stress in bisphenol AF-induced cardiotoxicity in zebrafish and the protective role of N-acetyl N-cysteine. The Science of the total environment. 731:139190

Holowiecki, A., Linstrum, K., Ravisankar, P., Chetal, K., Salomonis, N., Waxman, J.S. (2020) Pbx4 limits heart size and fosters arch artery formation through partitioning second heart field progenitors and restricting proliferation. Development (Cambridge, England). 147(5):

Huang, Y., Chen, Z., Meng, Y., Wei, Y., Xu, Z., Ma, J., Zhong, K., Cao, Z., Liao, X., Lu, H. (2020) Famoxadone-cymoxanil induced cardiotoxicity in zebrafish embryos. Ecotoxicology and environmental safety. 205:111339

Huang, Y., Ma, J., Meng, Y., Wei, Y., Xie, S., Jiang, P., Wang, Z., Chen, X., Liu, Z., Zhong, K., Cao, Z., Liao, X., Xiao, J., Lu, H. (2020) Exposure to Oxadiazon-Butachlor causes cardiac toxicity in zebrafish embryos. Environmental pollution (Barking, Essex : 1987). 265:114775

Kim, C., Choe, H., Park, J., Kim, G., Kim, K., Jeon, H.J., Moon, J.K., Kim, M.J., Lee, S.E. (2020) Molecular mechanisms of developmental toxicities of azoxystrobin and pyraclostrobin toward zebrafish (Danio rerio) embryos: Visualization of abnormal development using two transgenic lines. Environmental pollution (Barking, Essex : 1987). 270:116087

Kim, Y.C., Lee, S.R., Jeon, H.J., Kim, K., Kim, M.J., Choi, S.D., Lee, S.E. (2020) Acute toxicities of fluorene, fluorene-1-carboxylic acid, and fluorene-9-carboxylic acid on zebrafish embryos (Danio rerio): Molecular mechanisms of developmental toxicities of fluorene-1-carboxylic acid. Chemosphere. 260:127622

Kula-Alwar, D., Marber, M.S., Hughes, S.M., Hinits, Y. (2020) Mef2c factors are required for early but not late addition of cardiomyocytes to the ventricle. Developmental Biology. 470:95-107

Li, X., Lu, Q., Peng, Y., Geng, F., Shao, X., Zhou, H., Cao, Y., Zhang, R. (2020) Primary cilia mediate Klf2-dependant Notch activation in regenerating heart. Protein & cell. 11(6):433-445

Liu, Y., Lin, Z., Liu, M., Liao, H., Chen, Y., Zhang, X., Chan, H.C., Zhou, B., Rao, L., Sun, H. (2020) CFTR deficiency causes cardiac dysplasia during zebrafish embryogenesis and is associated with dilated cardiomyopathy. Mechanisms of Development. 163:103627

Liu, Y., Zhu, Z., Ho, I.H.T., Shi, Y., Li, J., Wang, X., Chan, M.T.V., Cheng, C.H.K. (2020) Genetic Deletion of miR-430 Disrupts Maternal-Zygotic Transition and Embryonic Body Plan. Frontiers in genetics. 11:853

Mao, A., Zhang, M., Li, L., Liu, J., Ning, G., Cao, Y., Wang, Q. (2020) Pharyngeal pouches provide a niche microenvironment for arch artery progenitor specification. Development (Cambridge, England). 148(2):

Mi, P., Tang, Y.Q., Feng, X.Z. (2020) Acute fluorene-9-bisphenol exposure damages early development and induces cardiotoxicity in zebrafish (Danio rerio). Ecotoxicology and environmental safety. 202:110922

Nguyen, T.H., Nguyen, P.D., Quetin-Leclercq, J., Muller, M., Ly Huong, D.T., Pham, H.T., Kestemont, P. (2020) Developmental toxicity of Clerodendrum cyrtophyllum turcz ethanol extract in zebrafish embryo. Journal of ethnopharmacology. 267:113538

Ren, F., Huang, Y., Tao, Y., Ji, C., Aniagu, S., Jiang, Y., Chen, T. (2020) Resveratrol protects against PM2.5-induced heart defects in zebrafish embryos as an antioxidant rather than as an AHR antagonist. Toxicology and applied pharmacology. 398:115029

Sam, J., Mercer, E.J., Torregroza, I., Banks, K.M., Evans, T. (2020) Specificity, redundancy and dosage thresholds among gata4/5/6 genes during zebrafish cardiogenesis. Biology Open. 9(6):

Santos-Ledo, A., Washer, S., Dhanaseelan, T., Eley, L., Alqatani, A., Chrystal, P.W., Papoutsi, T., Henderson, D.J., Chaudhry, B. (2020) Alternative splicing of jnk1a in zebrafish determines first heart field ventricular cardiomyocyte numbers through modulation of hand2 expression. PLoS Genetics. 16:e1008782

Shang, X., Ji, X., Dang, J., Wang, L., Sun, C., Liu, K., Sik, A., Jin, M. (2020) α-asarone induces cardiac defects and QT prolongation through mitochondrial apoptosis pathway in zebrafish. Toxicology letters. 324:1-11

She, P., Zhang, H., Peng, X., Sun, J., Gao, B., Zhou, Y., Zhu, X., Hu, X., Lai, K.S., Wong, J., Zhou, B., Wang, L., Zhong, T.P. (2020) The Gridlock transcriptional repressor impedes vertebrate heart regeneration by restricting expression of lysine methyltransferase. Development (Cambridge, England). 147(18):

Shi, Y., Li, Y., Wang, Y., Zhu, P., Chen, Y., Wang, H., Yue, S., Xia, X., Chen, J., Jiang, Z., Zhou, C., Cai, W., Yuan, H., Wu, Y., Wan, Y., Li, X., Zhu, X., Zhou, Z., Dai, G., Li, F., Mo, X., Ye, X., Fan, X., Zhuang, J., Wu, X., Yuan, W. (2020) BVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis. Scientific Reports. 10:14167

Sun, Y., Cao, Y., Tong, L., Tao, F., Wang, X., Wu, H., Wang, M. (2020) Exposure to prothioconazole induces developmental toxicity and cardiovascular effects on zebrafish embryo. Chemosphere. 251:126418

Takahashi, K., Ito, Y., Yoshimura, M., Nikaido, M., Yuikawa, T., Kawamura, A., Tsuda, S., Kage, D., Yamasu, K. (2020) A globin-family protein, cytoglobin 1, is involved in the development of neural crest-derived tissues and organs in zebrafish. Developmental Biology. 472:1-17

Tang, C., Shen, C., Zhu, K., Zhou, Y., Chuang, Y.J., He, C., Zuo, Z. (2020) Exposure to the AhR agonist cyprodinil impacts the cardiac development and function of zebrafish larvae. Ecotoxicology and environmental safety. 201:110808

Vandernoot, I., Haerlingen, B., Gillotay, P., Trubiroha, A., Janssens, V., Opitz, R., Costagliola, S. (2020) Enhanced canonical Wnt signaling during early zebrafish development perturbs the interaction of cardiac mesoderm and pharyngeal endoderm and causes thyroid specification defects. Thyroid : official journal of the American Thyroid Association. 31(3):420-438

Wang, D., Zhang, Y., Li, J., Dahlgren, R.A., Wang, X., Huang, H., Wang, H. (2020) Risk assessment of cardiotoxicity to zebrafish (Danio rerio) by environmental exposure to triclosan and its derivatives. Environmental pollution (Barking, Essex : 1987). 265:114995

Wei, Y., Meng, Y., Huang, Y., Liu, Z., Zhong, K., Ma, J., Zhang, W., Li, Y., Lu, H. (2020) Development toxicity and cardiotoxicity in zebrafish from exposure to iprodione. Chemosphere. 263:127860

Xia, Z.S., Wei, M., Wei, Y.T., Chen, Z.M., Hao, E.W., Hou, X.T., Du, Z.C., Deng, J.G. (2020) Genipin induces developmental toxicity through oxidative stress and apoptosis in zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 241:108951

Xiong, H., Huang, Y., Mao, Y., Liu, C., Wang, J. (2020) Inhibition in growth and cardiotoxicity of tris (2-butoxyethyl) phosphate through down-regulating Wnt signaling pathway in early developmental stage of zebrafish (Danio rerio). Ecotoxicology and environmental safety. 208:111431

Yin, H.M., Yan, L.F., Liu, Q., Peng, Z., Zhang, C.Y., Xia, Y., Su, D., Gu, A.H., Zhou, Y. (2020) Activating transcription factor 3 coordinates differentiation of cardiac and hematopoietic progenitors by regulating glucose metabolism. Science advances. 6:eaay9466

Zhang, Q., Liang, D., Yue, Y., He, L., Li, N., Jiang, D., Hu, P., Zhao, Q. (2020) Axenfeld-Rieger syndrome-associated mutants of the transcription factor FOXC1 abnormally regulate NKX2-5 in model zebrafish embryos. The Journal of biological chemistry. 295(33):11902-11913

Bornhorst, D., Xia, P., Nakajima, H., Dingare, C., Herzog, W., Lecaudey, V., Mochizuki, N., Heisenberg, C.P., Yelon, D., Abdelilah-Seyfried, S. (2019) Biomechanical signaling within the developing zebrafish heart attunes endocardial growth to myocardial chamber dimensions. Nature communications. 10:4113

Capasso, T.L., Li, B., Volek, H.J., Khalid, W., Rochon, E.R., Anbalagan, A., Herdman, C., Yost, H.J., Villanueva, F.S., Kim, K., Roman, B.L. (2019) BMP10-mediated ALK1 signaling is continuously required for vascular development and maintenance. Angiogenesis. 23(2):203-220

Dohn, T.E., Ravisankar, P., Tirera, F.T., Martin, K.E., Gafranek, J.T., Duong, T.B., VanDyke, T.L., Touvron, M., Barske, L.A., Crump, J.G., Waxman, J.S. (2019) Nr2f-dependent allocation of ventricular cardiomyocyte and pharyngeal muscle progenitors. PLoS Genetics. 15:e1007962

Gao, X., Zheng, P., Yang, L., Luo, H., Zhang, C., Qiu, Y., Huang, G., Sheng, W., Ma, X., Lu, C. (2019) Association of functional variant in GDF1 promoter with risk of congenital heart disease and its regulation by Nkx2.5. Clinical science (London, England : 1979). 133:1281-1295

Gardner, L.D., Peck, K.A., Goetz, G.W., Linbo, T.L., Cameron, J., Scholz, N.L., Block, B.A., Incardona, J.P. (2019) Cardiac remodeling in response to embryonic crude oil exposure involves unconventional NKX family members and innate immunity genes. The Journal of experimental biology. 222(Pt 21):

Gong, G., Kam, H., Tse, Y., Lee, S.M. (2019) Cardiotoxicity of forchlorfenuron (CPPU) in zebrafish (Danio rerio) and H9c2 cardiomyocytes. Chemosphere. 235:153-162

Gálvez-Santisteban, M., Chen, D., Zhang, R., Serrano, R., Nguyen, C., Zhao, L., Nerb, L., Masutani, E.M., Vermot, J., Burns, C.G., Burns, C.E., Del Álamo, J.C., Chi, N.C. (2019) Hemodynamic-mediated endocardial signaling controls in vivo myocardial reprogramming. eLIFE. 8:

Huang, M., Zhu, F., Jiao, J., Wang, J., Zhang, Y. (2019) Exposure to acrylamide disrupts cardiomyocyte interactions during ventricular morphogenesis in zebrafish embryos. The Science of the total environment. 656:1337-1345

Jin, H., Ji, C., Ren, F., Aniagu, S., Tong, J., Jiang, Y., Chen, T. (2019) AHR-mediated oxidative stress contributes to the cardiac developmental toxicity of trichloroethylene in zebrafish embryos. Journal of hazardous materials. 385:121521

Lan, Y., Pan, H., Li, C., Banks, K.M., Sam, J., Ding, B., Elemento, O., Goll, M.G., Evans, T. (2019) TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis. Cell Reports. 26:720-732.e4

Li, M., Zhang, T., Jia, Y., Sun, Y., Zhang, S., Mi, P., Feng, Z., Zhao, X., Chen, D., Feng, X. (2019) Combined treatment of melatonin and sodium tanshinone IIA sulfonate reduced the neurological and cardiovascular toxicity induced by deltamethrin in zebrafish. Chemosphere. 243:125373

Liu, F., Han, X., Li, N., Liu, K., Kang, W. (2019) Aconitum alkaloids induce cardiotoxicity and apoptosis in embryonic zebrafish by influencing the expression of cardiovascular relative genes. Toxicology letters. 305:10-18

Maerz, L.D., Burkhalter, M.D., Schilpp, C., Wittekindt, O.H., Frick, M., Philipp, M. (2019) Pharmacological cholesterol depletion disturbs ciliogenesis and ciliary function in developing zebrafish. Communications biology. 2:31

Mao, A., Zhang, M., Liu, J., Cao, Y., Wang, Q. (2019) PDGF signaling from pharyngeal pouches promotes arch artery morphogenesis. Journal of genetics and genomics = Yi chuan xue bao. 46(12):551-559

Pawlak, M., Kedzierska, K.Z., Migdal, M., Nahia, K.A., Ramilowski, J.A., Bugajski, L., Hashimoto, K., Marconi, A., Piwocka, K., Carninci, P., Winata, C.L. (2019) Dynamics of cardiomyocyte transcriptome and chromatin landscape demarcates key events of heart development. Genome research. 29(3):506-519

Philibert, D.A., Lyons, D.D., Qin, R., Huang, R., El-Din, M.G., Tierney, K.B. (2019) Persistent and transgenerational effects of raw and ozonated oil sands process-affected water exposure on a model vertebrate, the zebrafish. The Science of the total environment. 693:133611

Ren, F., Ji, C., Huang, Y., Aniagu, S., Jiang, Y., Chen, T. (2019) AHR-mediated ROS production contributes to the cardiac developmental toxicity of PM2.5 in zebrafish embryos. The Science of the total environment. 719:135097

Ren, J., Han, P., Ma, X., Farah, E.N., Bloomekatz, J., Zeng, X.I., Zhang, R., Swim, M.M., Witty, A.D., Knight, H.G., Deshpande, R., Xu, W., Yelon, D., Chen, S., Chi, N.C. (2019) Canonical Wnt5b Signaling Directs Outlying Nkx2.5+ Mesoderm into Pacemaker Cardiomyocytes. Developmental Cell. 50(6):729-743.e5

Sehonova, P., Hodkovicova, N., Urbanova, M., Örn, S., Blahova, J., Svobodova, Z., Faldyna, M., Chloupek, P., Briedikova, K., Carlsson, G. (2019) Effects of antidepressants with different modes of action on early life stages of fish and amphibians. Environmental pollution (Barking, Essex : 1987). 254:112999

Song, Y.C., Dohn, T.E., Rydeen, A.B., Nechiporuk, A.V., Waxman, J.S. (2019) HDAC1-mediated repression of the retinoic acid-responsive gene ripply3 promotes second heart field development. PLoS Genetics. 15:e1008165

Wang, F., Yang, Q., Wu, F., Zhang, Y., Sun, S., Wang, X., Gui, Y., Li, Q. (2019) Identification of a 42-bp heart-specific enhancer of the notch1b gene in zebrafish embryos. Developmental Dynamics : an official publication of the American Association of Anatomists. 248(6):426-436

Wang, W., Wang, B., Liu, Z., Xia, X. (2019) Developmental toxicity and alteration of gene expression in zebrafish embryo exposed to 6-benzylaminopurine. Chemosphere. 233:336-346

Wu, Y., Zhang, Y., Chen, M., Yang, Q., Zhuang, S., Lv, L., Zuo, Z., Wang, C. (2019) Exposure to low-level metalaxyl impacts the cardiac development and function of zebrafish embryos. Journal of environmental sciences (China). 85:1-8

Xie, S., Fu, W., Yu, G., Hu, X., Lai, K.S., Peng, X., Zhou, Y., Zhu, X., Christov, P., Sawyer, L., Ni, T.T., Sulikowski, G.A., Yang, Z., Lee, E., Zeng, C., Wang, W.E., Zhong, T.P. (2019) Discovering small molecules as Wnt inhibitors that promote heart regeneration and injury repair. Journal of molecular cell biology. 12(1):42-54

Zhang, K., Yuan, G., Werdich, A.A., Zhao, Y. (2019) Ibuprofen and diclofenac impair the cardiovascular development of zebrafish (Danio rerio) at low concentrations. Environmental pollution (Barking, Essex : 1987). 258:113613

Babu, A., Kamaraj, M., Basu, M., Mukherjee, D., Kapoor, S., Ranjan, S., Swamy, M.M., Kaypee, S., Scaria, V., Kundu, T.K., Sachidanandan, C. (2018) Chemical and genetic rescue of an ep300 knockdown model for Rubinstein Taybi syndrome in zebrafish. Biochimica et biophysica acta. 1864(4 Pt A):1203-1215

Cantù, C., Felker, A., Zimmerli, D., Prummel, K.D., Cabello, E.M., Chiavacci, E., Méndez-Acevedo, K.M., Kirchgeorg, L., Burger, S., Ripoll, J., Valenta, T., Hausmann, G., Vilain, N., Aguet, M., Burger, A., Panáková, D., Basler, K., Mosimann, C. (2018) Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling.. Genes & Development. 32(21-22):1443-1458

Castillo-Robles, J., Ramírez, L., Spaink, H.P., Lomelí, H. (2018) smarce1 mutants have a defective endocardium and an increased expression of cardiac transcription factors in zebrafish. Scientific Reports. 8:15369

Fukui, H., Miyazaki, T., Chow, R.W., Ishikawa, H., Nakajima, H., Vermot, J., Mochizuki, N. (2018) Hippo signaling determines the number of venous pole cells that originate from the anterior lateral plate mesoderm in zebrafish. eLIFE. 7

Gawdzik, J.C., Yue, M.S., Martin, N.R., Elemans, L.M.H., Lanham, K.A., Heideman, W., Rezendes, R., Baker, T.R., Taylor, M.R., Plavicki, J.S. (2018) sox9b is required in cardiomyocytes for cardiac morphogenesis and function. Scientific Reports. 8:13906

Gibb, N., Lazic, S., Yuan, X., Deshwar, A.R., Leslie, M., Wilson, M.D., Scott, I.C. (2018) Hey2 regulates the size of the cardiac progenitor pool during vertebrate heart development. Development (Cambridge, England). 145(22):

Guner-Ataman, B., González-Rosa, J.M., Shah, H.N., Butty, V.L., Jeffrey, S., Abrial, M., Boyer, L.A., Burns, C.G., Burns, C.E. (2018) Failed Progenitor Specification Underlies the Cardiopharyngeal Phenotypes in a Zebrafish Model of 22q11.2 Deletion Syndrome. Cell Reports. 24:1342-1354.e5

Guzzolino, E., Chiavacci, E., Ahuja, N., Mariani, L., Evangelista, M., Ippolito, C., Rizzo, M., Garrity, D., Cremisi, F., Pitto, L. (2018) Post-transcriptional Modulation of Sphingosine-1-Phosphate Receptor 1 by miR-19a Affects Cardiovascular Development in Zebrafish. Frontiers in cell and developmental biology. 6:58

Hofsteen, P., Robitaille, A.M., Strash, N., Palpant, N., Moon, R.T., Pabon, L., Murry, C.E. (2018) ALPK2 Promotes Cardiogenesis in Zebrafish and Human Pluripotent Stem Cells. iScience. 2:88-100

Huang, C.X., Huang, Y., Duan, X.K., Zhang, M., Tu, J.P., Liu, J.X., Liu, H., Chen, T.S., Wang, W.M., Wang, H.L. (2018) Zebrafish miR-462-731 regulates hematopoietic specification and pu.1-dependent primitive myelopoiesis. Cell death and differentiation. 26(8):1531-1544

Jin, M., Xiao, Z., Zhang, S., Men, X., Li, X., Zhang, B., Zhou, T., Hsiao, C.D., Liu, K. (2018) Possible involvement of Fas/FasL-dependent apoptotic pathway in α-bisabolol induced cardiotoxicity in zebrafish embryos. Chemosphere. 219:557-566

Kim, K., Wang, C.H., Ok, Y.S., Lee, S.E. (2018) Heart developmental toxicity by carbon black waste generated from oil refinery on zebrafish embryos (Danio rerio): Combined toxicity on heart function by nickel and vanadium. Journal of hazardous materials. 363:127-137

Ladam, F., Stanney, W., Donaldson, I.J., Yildiz, O., Bobola, N., Sagerström, C.G. (2018) TALE factors use two distinct functional modes to control an essential zebrafish gene expression program. eLIFE. 7

Lyons, D.D., Philibert, D.A., Zablocki, T., Qin, R., Huang, R., Gamal El-Din, M., Tierney, K.B. (2018) Assessment of raw and ozonated oil sands process-affected water exposure in developing zebrafish: Associating morphological changes with gene expression. Environmental pollution (Barking, Essex : 1987). 241:959-968

Meng, J., Xu, W.Y., Chen, X., Lin, T., Deng, X.Y. (2018) Gene locations may contribute to predicting gene regulatory relationships. Journal of Zhejiang University. Science. B. 19:25-37

Moore, C., Richens, J.L., Hough, Y., Ucanok, D., Malla, S., Sang, F., Chen, Y., Elworthy, S., Wilkinson, R.N., Gering, M. (2018) Gfi1aa and Gfi1b set the pace for primitive erythroblast differentiation from hemangioblasts in the zebrafish embryo. Blood advances. 2:2589-2606

Philibert, D.A., Lyons, D., Philibert, C., Tierney, K.B. (2018) Field-collected crude oil, weathered oil and dispersants differentially affect the early life stages of freshwater and saltwater fishes. The Science of the total environment. 647:1148-1157

Saydmohammed, M., Vollmer, L.L., Onuoha, E.O., Maskrey, T.S., Gibson, G., Watkins, S.C., Wipf, P., Vogt, A., Tsang, M. (2018) A High-Content Screen Reveals New Small-Molecule Enhancers of Ras/Mapk Signaling as Probes for Zebrafish Heart Development. Molecules. 23(7)

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Additional Citations (21):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

Ensembl curators, GOA curators (2006) Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara. Manually curated data.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, C., and Thisse, B. (2005) High Throughput Expression Analysis of ZF-Models Consortium Clones. ZFIN Direct Data Submission.

Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Computational Sequence to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.