ZFIN ID: ZDB-PERS-960805-635
Zon, Leonard I.
Email: zon@enders.tch.harvard.edu
URL: http://zon.tchlab.org
Affiliation: The Zon Lab
Address: Howard Hughes Medical Institute Children's Hospital Boston Division of Hematology/Oncology 300 Longwood Avenue, Karp 8 Boston, MA 02115 USA
Country: United States
Phone: (617) 919-2069
Fax: (617) 355-7262
Orcid ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Ciarlo, C., Kaufman, C.K., Kinikoglu, B., Michael, J., Yang, S., D Amato, C., Blokzijl-Franke, S., den Hertog, J., Schlaeger, T.M., Zhou, Y., Liao, E., Zon, L.I. (2017) A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development. eLIFE. 6
Fazio, M., Avagyan, S., van Rooijen, E., Mannherz, W., Kaufman, C.K., Lobbardi, R., Langenau, D.M., Zon, L.I. (2017) Efficient Transduction of Zebrafish Melanoma Cell Lines and Embryos Using Lentiviral Vectors. Zebrafish. 14(4):379-382
van Rooijen, E., Fazio, M., Zon, L.I. (2017) From fish bowl to bedside: The power of zebrafish to unravel melanoma pathogenesis and discover new therapeutics. Pigment cell & melanoma research. 30(4):402-412
Khajavi, M., Zhou, Y., Birsner, A.E., Bazinet, L., Di Sant, A.R., Schiffer, A.J., Rogers, M.S., Krishnaji, S.T., Hu, B., Nguyen, V., Zon, L., D'Amato, R.J. (2017) Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice. PLoS Genetics. 13:e1006848
Choudhuri, A., Fast, E.M., Zon, L.I. (2017) Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration. Stem Cell Reports. 8:1465-1471
Theodore, L.N., Hagedorn, E.J., Cortes, M., Natsuhara, K., Liu, S.Y., Perlin, J.R., Yang, S., Daily, M.L., Zon, L.I., North, T.E. (2017) Distinct Roles for Matrix Metalloproteinases 2 and 9 in Embryonic Hematopoietic Stem Cell Emergence, Migration, and Niche Colonization. Stem Cell Reports. 8(5):1226-1241
Hockman, D., Burns, A., Schlosser, G., Gates, K.P., Jevans, B., Mongera, A., Fisher, S., Unlu, G., Knapik, E.W., Kaufman, C.K., Mosimann, C., Zon, L.I., Lancman, J.J., Dong, P.D., Lickert, H., Tucker, A.S., Baker, C.V. (2017) Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes. eLIFE. 6
Blaser, B.W., Moore, J.L., Hagedorn, E.J., Li, B., Riquelme, R., Lichtig, A., Yang, S., Zhou, Y., Tamplin, O.J., Binder, V., Zon, L.I. (2017) CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. The Journal of experimental medicine. 214(4):1011
Gansner, J.M., Leung, A.D., Superdock, M., Blair, M.C., Ammerman, M.B., Durand, E.M., Barut, B., Handin, R.I., Stachura, D.L., Lu, C., Springer, T.A., Zon, L.I. (2017) Sorting zebrafish thrombocyte lineage cells with a Cd41 monoclonal antibody enriches hematopoietic stem cell activity. Blood.
Volpi, S., Yamazaki, Y., Brauer, P.M., van Rooijen, E., Hayashida, A., Slavotinek, A., Sun Kuehn, H., Di Rocco, M., Rivolta, C., Bortolomai, I., Du, L., Felgentreff, K., Ott de Bruin, L., Hayashida, K., Freedman, G., Marcovecchio, G.E., Capuder, K., Rath, P., Luche, N., Hagedorn, E.J., Buoncompagni, A., Royer-Bertrand, B., Giliani, S., Poliani, P.L., Imberti, L., Dobbs, K., Poulain, F.E., Martini, A., Manis, J., Linhardt, R.J., Bosticardo, M., Rosenzweig, S.D., Lee, H., Puck, J.M., Zúñiga-Pflücker, J.C., Zon, L., Park, P.W., Superti-Furga, A., Notarangelo, L.D. (2017) EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay. The Journal of experimental medicine. 214(3):623-637
van Rooij, F.J., Qayyum, R., Smith, A.V., Zhou, Y., Trompet, S., Tanaka, T., Keller, M.F., Chang, L.C., Schmidt, H., Yang, M.L., Chen, M.H., Hayes, J., Johnson, A.D., Yanek, L.R., Mueller, C., Lange, L., Floyd, J.S., Ghanbari, M., Zonderman, A.B., Jukema, J.W., Hofman, A., van Duijn, C.M., Desch, K.C., Saba, Y., Ozel, A.B., Snively, B.M., Wu, J.Y., Schmidt, R., Fornage, M., Klein, R.J., Fox, C.S., Matsuda, K., Kamatani, N., Wild, P.S., Stott, D.J., Ford, I., Slagboom, P.E., Yang, J., Chu, A.Y., Lambert, A.J., Uitterlinden, A.G., Franco, O.H., Hofer, E., Ginsburg, D., Hu, B., Keating, B., Schick, U.M., Brody, J.A., Li, J.Z., Chen, Z., Zeller, T., Guralnik, J.M., Chasman, D.I., Peters, L.L., Kubo, M., Becker, D.M., Li, J., Eiriksdottir, G., Rotter, J.I., Levy, D., Grossmann, V., Patel, K.V., Chen, C.H., Ridker, P.M., Tang, H., Launer, L.J., Rice, K.M., Li-Gao, R., Ferrucci, L., Evans, M.K., Choudhuri, A., Trompouki, E., Abraham, B.J., Yang, S., Takahashi, A., Kamatani, Y., Kooperberg, C., Harris, T.B., Jee, S.H., Coresh, J., Tsai, F.J., Longo, D.L., Chen, Y.T., Felix, J.F., Yang, Q., Psaty, B.M., Boerwinkle, E., Becker, L.C., Mook-Kanamori, D.O., Wilson, J.G., Gudnason, V., O'Donnell, C.J., Dehghan, A., Cupples, L.A., Nalls, M.A., Morris, A.P., Okada, Y., Reiner, A.P., Zon, L.I., Ganesh, S.K. (2017) Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. American journal of human genetics. 100(1):51-63
Henninger, J., Santoso, B., Hans, S., Durand, E., Moore, J., Mosimann, C., Brand, M., Traver, D., Zon, L. (2017) Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development. Nature Cell Biology. 19(1):17-27
Gansner, J.M., Dang, M., Ammerman, M., Zon, L.I. (2017) Transplantation in zebrafish. Methods in cell biology. 138:629-647
Wiley, D.S., Redfield, S.E., Zon, L.I. (2017) Chemical screening in zebrafish for novel biological and therapeutic discovery. Methods in cell biology. 138:651-679
Liu, W., Wu, M., Huang, Z., Lian, J., Chen, J., Wang, T., Leung, A.Y., Liao, Y., Zhang, Z., Liu, Q., Yen, K., Lin, S., Zon, L.I., Wen, Z., Zhang, Y., Zhang, W. (2017) c-myb hyperactivity leads to myeloid and lymphoid malignancies in zebrafish. Leukemia. 31(1):222-233
Robertson, A.L., Avagyan, S., Gansner, J.M., Zon, L.I. (2016) Understanding the regulation of vertebrate hematopoiesis and blood disorders: big lessons from a small fish. FEBS letters. 590(22):4016-4033
Ray, M.K., Wiskow, O., King, M.J., Ismail, N., Ergun, A., Wang, Y., Plys, A.J., Davis, C.P., Kathrein, K., Sadreyev, R., Borowsky, M.L., Eggan, K., Zon, L., Galloway, J.L., Kingston, R.E. (2016) CAT7 and cat7l long non-coding RNAs Tune Polycomb Repressive Complex 1 Function During Human and Zebrafish Development. The Journal of biological chemistry. 291(37):19558-72
Pankratz, N., Schick, U. M., Zhou, Y., Zhou, W., Ahluwalia, T. S., Allende, M. L., Auer, P. L., Bork-Jensen, J., Brody, J. A., Chen, M. H., Clavo, V., Eicher, J. D., Grarup, N., Hagedorn, E. J., Hu, B., Hunker, K., Johnson, A. D., Leusink, M., Lu, Y., Lyytikäinen, L. P., Manichaikul, A., Marioni, R. E., Nalls, M. A., Pazoki, R., Smith, A. V., van Rooij, F. J., Yang, M. L, Zhang, X., Zhang, Y., Asselbergs, F. W., Boerwinkle, E., Borecki, I. B., Bottinger, E. P., Cushman, M., de Bakker, P. I., Deary, I. J., Dong, L., Feitosa, M. F., Floyd, J. S., Franceschini, N., Franco, O. H., Garcia, M. E., Grove, M. L., Gudnason, V., Hansen, T., Harris, T. B., Hofman, A., Jackson, R. D., Jia, J., Kähönen, M., Launer, L. J., Lehtimäki, T., Liewald, D. C., Linneberg, A., Liu, Y., Loos, R. J., Nguyen, V. M., Numans, M. E., Pedersen, O., Psaty, B. M., Raitakari, O. T., Rich, S. S., Rivadeneira, F., Di Sant, A. M., Rotter, J. I., Starr, J. M., Taylor, K. D., Thuesen, B. H., Tracy, R. P., Uitterlinden, A. G., Wang, J., Wang, J., Dehghan, A., Huo, Y., Cupples, L. A., Wilson, J. G., Proia, R. L., Zon, L. I., O'Donnell, C. J., Reiner, A. P., Ganesh, S. K. (2016) Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits. Nature Genetics. 48(8):867-76
Dang, M., Henderson, R.E., Garraway, L.A., Zon, L.I. (2016) Long-term drug administration in the adult zebrafish using oral gavage for cancer preclinical studies. Disease models & mechanisms. 9:811-20
Hagedorn, E.J., Cillis, J.L., Curley, C.R., Patch, T.C., Li, B., Blaser, B.W., Riquelme, R., Zon, L.I., Shah, D.I. (2016) Generation of Parabiotic Zebrafish Embryos by Surgical Fusion of Developing Blastulae. Journal of visualized experiments : JoVE. (112)
Rowe, R.G., Mandelbaum, J., Zon, L.I., Daley, G.Q. (2016) Engineering Hematopoietic Stem Cells: Lessons from Development. Cell Stem Cell. 18:707-720
Adatto, I., Krug, L., Zon, L.I. (2016) The Red Light District and Its Effects on Zebrafish Reproduction. Zebrafish. 13(3):226-9
Zon, L. (2016) Modeling human diseases: an education in interactions and interdisciplinary approaches. Disease models & mechanisms. 9:597-600
Svoboda, O., Stachura, D.L., Machonova, O., Zon, L.I., Traver, D., Bartunek, P. (2016) Ex vivo tools for the clonal analysis of zebrafish hematopoiesis. Nature Protocols. 11:1007-1020
Tan, J.L., Fogley, R.D., Flynn, R.A., Ablain, J., Yang, S., Saint-André, V., Fan, Z.P., Do, B.T., Laga, A.C., Fujinaga, K., Santoriello, C., Greer, C.B., Kim, Y.J., Clohessy, J.G., Bothmer, A., Pandell, N., Avagyan, S., Brogie, J.E., van Rooijen, E., Hagedorn, E.J., Shyh-Chang, N., White, R.M., Price, D.H., Pandolfi, P.P., Peterlin, B.M., Zhou, Y., Kim, T.H., Asara, J.M., Chang, H.Y., Young, R.A., Zon, L.I. (2016) Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Molecular Cell. 62:34-46
Avagyan, S., Zon, L.I. (2016) Fish to Learn: Insights into Blood Development and Blood Disorders from Zebrafish Hematopoiesis. Human gene therapy. 27(4):287-94
Gao, X., Wu, T., Johnson, K.D., Lahvic, J.L., Ranheim, E.A., Zon, L.I., Bresnick, E.H. (2016) GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis. Stem Cell Reports. 6(3):368-82
Dang, M., Fogley, R., Zon, L.I. (2016) Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish. Advances in experimental medicine and biology. 916:103-24
Yang, S., Ott, C.J., Rossmann, M.P., Superdock, M., Zon, L.I., Zhou, Y. (2016) Chromatin immunoprecipitation and an open chromatin assay in zebrafish erythrocytes. Methods in cell biology. 135:387-412
Ablain, J., Zon, L.I. (2016) Tissue-specific gene targeting using CRISPR/Cas9. Methods in cell biology. 135:189-202
Ciarlo, C.A., Zon, L.I. (2016) Embryonic cell culture in zebrafish. Methods in cell biology. 133:1-10
Anderson, H., Patch, T.C., Reddy, P.N., Hagedorn, E.J., Kim, P.G., Soltis, K.A., Chen, M.J., Tamplin, O.J., Frye, M., MacLean, G.A., Hübner, K., Bauer, D.E., Kanki, J.P., Vogin, G., Huston, N.C., Nguyen, M., Fujiwara, Y., Paw, B.H., Vestweber, D., Zon, L.I., Orkin, S.H., Daley, G.Q., Shah, D.I. (2015) Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression. Blood. 126(26):2811-20
Peng, X., Dong, M., Ma, L., Jia, X.E., Mao, J., Jin, C., Chen, Y., Gao, L., Liu, X., Ma, K., Wang, L., Du, T., Jin, Y., Huang, Q., Li, K., Zon, L.I., Liu, T., Deng, M., Zhou, Y., Xi, X., Zhou, Y., Chen, S. (2015) A point mutation of zebrafish c-cbl gene in the ring finger domain produces a phenotype mimicking human myeloproliferative disease. Leukemia. 29(12):2355-65
Heilmann, S., Ratnakumar, K., Langdon, E., Kansler, E., Kim, I., Campbell, N.R., Perry, E., McMahon, A., Kaufman, C., van Rooijen, E., Lee, W., Iacobuzio-Donahue, C., Hynes, R., Zon, L., Xavier, J., White, R.M. (2015) A quantitative system for studying metastasis using transparent zebrafish. Cancer research. 75(20):4272-82
Musso, G., Mosimann, C., Panáková, D., Burger, A., Zhou, Y., Zon, L.I., MacRae, C.A. (2015) Generating and evaluating a ranked candidate gene list for potential vertebrate heart field regulators. Genomics Data. 6:199-201
Mosimann, C., Panáková, D., Werdich, A.A., Musso, G., Burger, A., Lawson, K.L., Carr, L.A., Nevis, K.R., Sabeh, M.K., Zhou, Y., Davidson, A.J., DiBiase, A., Burns, C.E., Burns, C.G., MacRae, C.A., Zon, L.I. (2015) Chamber identity programs drive early functional partitioning of the heart. Nature communications. 6:8146
Jia, X.E., Ma, K., Xu, T., Gao, L., Wu, S., Fu, C., Zhang, W., Wang, Z., Liu, K., Dong, M., Jing, C., Ren, C., Dong, Z., Chen, Y., Jin, Y., Huang, Q., Chang, X., Deng, M., Li, L., Luo, L., Zhu, J., Dang, Y., Chang, H.C., Zon, L.I., Zhou, Y., Chen, S., Pan, W. (2015) Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell Research. 25(8):946-62
Li, P., Lahvic, J.L., Binder, V., Pugach, E.K., Riley, E.B., Tamplin, O.J., Panigrahy, D., Bowman, T.V., Barrett, F.G., Heffner, G.C., McKinney-Freeman, S., Schlaeger, T.M., Daley, G.Q., Zeldin, D.C., Zon, L.I. (2015) Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature. 523:468-71
Gao, L., Li, D., Ma, K., Zhang, W., Xu, T., Fu, C., Jing, C., Jia, X., Wu, S., Sun, X., Dong, M., Deng, M., Chen, Y., Zhu, W., Peng, J., Wan, F., Zhou, Y., Zon, L.I., Pan, W. (2015) TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis. PLoS Genetics. 11:e1005346
Jing, L., Tamplin, O.J., Chen, M.J., Deng, Q., Patterson, S., Kim, P.G., Durand, E.M., McNeil, A., Green, J.M., Matsuura, S., Ablain, J., Brandt, M.K., Schlaeger, T.M., Huttenlocher, A., Daley, G.Q., Ravid, K., Zon, L.I. (2015) Adenosine signaling promotes hematopoietic stem and progenitor cell emergence. The Journal of experimental medicine. 212(5):649-63
Ablain, J., Durand, E.M., Yang, S., Zhou, Y., Zon, L.I. (2015) A CRISPR/Cas9 Vector System for Tissue-Specific Gene Disruption in Zebrafish. Developmental Cell. 32(6):756-64
Gjini, E., Mansour, M.R., Sander, J.D., Moritz, N., Nguyen, A.T., Kesarsing, M., Gans, E., He, S., Chen, S., Ko, M., Kuang, Y.Y., Yang, S., Zhou, Y., Rodig, S., Zon, L.I., Joung, J.K., Rao, A., Look, A.T. (2015) A Zebrafish Model of Myelodysplastic Syndrome Produced Through tet2 Genomic Editing. Molecular and cellular biology. 35(5):789-804
Jang, I.H., Lu, Y.F., Zhao, L., Wenzel, P.L., Kume, T., Datta, S.M., Arora, N., Guiu, J., Lagha, M., Kim, P.G., Do, E.K., Kim, J.H., Schlaeger, T.M., Zon, L.I., Bigas, A., Burns, C.E., Daley, G.Q. (2015) Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium. Blood. 125(9):1418-26
Lin, M.I., Price, E.N., Boatman, S., Hagedorn, E.J., Trompouki, E., Satishchandran, S., Carspecken, C.W., Uong, A., DiBiase, A., Yang, S., Canver, M.C., Dahlberg, A., Lu, Z., Zhang, C.C., Orkin, S.H., Bernstein, I.D., Aster, J.C., White, R.M., Zon, L.I. (2015) Angiopoietin-like proteins stimulate HSPC development through interaction with Notch receptor signaling. eLIFE. 4
Liu, X., Jia, X., Yuan, H., Ma, K., Chen, Y., Jin, Y., Deng, M., Pan, W., Chen, S., Chen, Z., de The, H., Zon, L.I., Zhou, Y., Zhou, J., Zhu, J. (2015) DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish. Journal of Hematology & Oncology. 8:15
Tamplin, O.J., Durand, E.M., Carr, L.A., Childs, S.J., Hagedorn, E.J., Li, P., Yzaguirre, A.D., Speck, N.A., Zon, L.I. (2015) Hematopoietic Stem Cell Arrival Triggers Dynamic Remodeling of the Perivascular Niche. Cell. 160:241-252
Hagedorn, E.J., Durand, E.M., Fast, E.M., Zon, L.I. (2014) Getting more for your marrow: Boosting hematopoietic stem cell numbers with PGE2. Experimental cell research. 329(2):220-226
Thornton, J.E., Du, P., Jing, L., Sjekloca, L., Lin, S., Grossi, E., Sliz, P., Zon, L.I., Gregory, R.I. (2014) Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4). Nucleic acids research. 42(18):11777-91
Guo, C., Chen, X., Song, H., Maynard, M.A., Zhou, Y., Lobanov, A.V., Gladyshev, V.N., Ganis, J.J., Wiley, D., Jugo, R.H., Lee, N.Y., Castroneves, L.A., Zon, L.I., Scanlan, T.S., Feldman, H.A., Huang, S.A. (2014) Intrinsic Expression of a Multiexon Type 3 Deiodinase Gene Controls Zebrafish Embryo Size. Endocrinology. 155(10):4069-80
Svoboda, O., Stachura, D.L., Machonova, O., Pajer, P., Brynda, J., Zon, L.I., Traver, D., Bartunek, P. (2014) Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin. Blood. 124(2):220-8
Mirabello, L., Macari, E.R., Jessop, L., Ellis, S.R., Myers, T., Giri, N., Taylor, A.M., McGrath, K.E., Humphries, J.M., Ballew, B.J., Yeager, M., Boland, J.F., He, J., Hicks, B.D., Burdett, L., Alter, B.P., Zon, L., Savage, S.A. (2014) Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multi-case Diamond-Blackfan anemia families. Blood. 124(1):24-32
Zon, L., Cagan, R. (2014) From fish tank to bedside in cancer therapy: an interview with Leonard Zon. Disease models & mechanisms. 7:735-8
Zhang, X., Ling, J., Barcia, G., Jing, L., Wu, J., Barry, B.J., Mochida, G.H., Hill, R.S., Weimer, J.M., Stein, Q., Poduri, A., Partlow, J.N., Ville, D., Dulac, O., Yu, T.W., Lam, A.T., Servattalab, S., Rodriguez, J., Boddaert, N., Munnich, A., Colleaux, L., Zon, L.I., Söll, D., Walsh, C.A., Nabbout, R. (2014) Mutations in QARS, Encoding Glutaminyl-tRNA Synthetase, Cause Progressive Microcephaly, Cerebral-Cerebellar Atrophy, and Intractable Seizures. American journal of human genetics. 94:547-58
Zhao, C., Andreeva, V., Gibert, Y., LaBonty, M., Lattanzi, V., Prabhudesai, S., Zhou, Y., Zon, L., McCann, K.L., Baserga, S., and Yelick, P.C. (2014) Tissue specific roles for the ribosome biogenesis factor Wdr43 in zebrafish development. PLoS Genetics. 10(1):e1004074
Alcaraz-Pérez, F., García-Castillo, J., García-Moreno, D., López-Muñoz, A., Anchelin, M., Angosto, D., Zon, L.I., Mulero, V., and Cayuela, M.L. (2014) A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish. Nature communications. 5:3228
Musso, G., Tasan, M., Mosimann, C., Beaver, J.E., Plovie, E., Carr, L.A., Chua, H.N., Dunham, J., Zuberi, K., Rodriguez, H., Morris, Q., Zon, L., Roth, F.P., and MacRae, C.A. (2014) Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish. Development (Cambridge, England). 141(1):224-235
Stachura, D.L., Svoboda, O., Campbell, C.A., Espín-Palazón, R., Lau, R.P., Zon, L.I., Bartunek, P., and Traver, D. (2013) The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance. Blood. 122(24):3918-28
Chen, C.H., Durand, E., Wang, J., Zon, L.I., and Poss, K.D. (2013) zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish. Development (Cambridge, England). 140(24):4988-97
Ablain, J., and Zon, L.I. (2013) Of fish and men: using zebrafish to fight human diseases. Trends in cell biology. 23(12):584-586
Huang, H.T., Kathrein, K.L., Barton, A., Gitlin, Z., Huang, Y.H., Ward, T.P., Hofmann, O., Dibiase, A., Song, A., Tyekucheva, S., Hide, W., Zhou, Y., and Zon, L.I. (2013) A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nat. Cell Biol.. 15(12):1516-1525
Xu, C., Tabebordbar, M., Iovino, S., Ciarlo, C., Liu, J., Castiglioni, A., Price, E., Liu, M., Barton, E.R., Kahn, C.R., Wagers, A.J., and Zon, L.I. (2013) A Zebrafish Embryo Culture System Defines Factors that Promote Vertebrate Myogenesis across Species. Cell. 155(4):909-921
Paik, E.J., Mahony, S., White, R.M., Price, E.N., Dibiase, A., Dorjsuren, B., Mosimann, C., Davidson, A.J., Gifford, D., and Zon, L.I. (2013) A cdx4-sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis. Stem Cell Reports. 1(5):425-436
White, R., Rose, K., and Zon, L. (2013) Zebrafish cancer: the state of the art and the path forward. Nature reviews. Cancer. 3(9):624-636
Mosimann, C., Puller, A.C., Lawson, K.L., Tschopp, P., Amsterdam, A., and Zon, L.I. (2013) Site-directed zebrafish transgenesis into single landing sites with the phiC31 integrase system. Developmental dynamics : an official publication of the American Association of Anatomists. 242(8):949-63
Storer, N.Y., White, R.M., Uong, A., Price, E., Nielsen, G.P., Langenau, D.M., and Zon, L.I. (2013) Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis. Development (Cambridge, England). 140(14):3040-3050
Jagannathan-Bogdan, M., and Zon, L.I. (2013) Hematopoiesis. Development (Cambridge, England). 140(12):2463-2467
Le, X., Pugach, E.K., Hettmer, S., Storer, N.Y., Liu, J., Wills, A.A., Dibiase, A., Chen, E.Y., Ignatius, M.S., Poss, K.D., Wagers, A.J., Langenau, D.M., and Zon, L.I. (2013) A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development. Development (Cambridge, England). 140(11):2354-64
Albacker, C.E., Storer, N.Y., Langdon, E.M., Dibiase, A., Zhou, Y., Langenau, D.M., and Zon, L.I. (2013) The Histone Methyltransferase SUV39H1 Suppresses Embryonal Rhabdomyosarcoma Formation in Zebrafish. PLoS One. 8(5):e64969
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