PUBLICATION

Zebrafish: a model system for the study of human disease

Authors
Dooley, K. and Zon, L.I.
ID
ZDB-PUB-000621-2
Date
2000
Source
Current opinion in genetics & development   10(3): 252-256 (Review)
Registered Authors
Dooley, Kim, Zon, Leonard I.
Keywords
none
MeSH Terms
  • Animals
  • Genetic Diseases, Inborn/genetics*
  • Genetics, Medical*
  • Humans
  • Models, Genetic*
  • Zebrafish/genetics*
PubMed
10826982 Full text @ Curr. Opin. Genet. Dev.
Abstract
The zebrafish (Danio rerio) is a powerful model organism for the study of vertebrate biology, being well suited to both developmental and genetic analysis. Large-scale genetic screens have identified hundreds of mutant phenotypes, many of which resemble human clinical disorders. The creation of critical genetic reagents, coupled with the rapid progress of the zebrafish genome initiative directed by the National Institutes of Health, are bringing this model system to its full potential for the study of vertebrate biology, physiology and human disease.
Genes / Markers
Figures
Show all Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes