ZFIN

ZFIN ID: ZDB-GENE-000626-1

ZFIN ID: ZDB-GENE-000626-1

CITATIONS (320 total)

Gene Name:	troponin T type 2a (cardiac)
Gene Symbol:	tnnt2a

Angom, R.S., Joshi, A., Patowary, A., Sivadas, A., Ramasamy, S., K V, S., Kaushik, K., Sabharwal, A., Lalwani, M.K., K, S., Singh, N., Scaria, V., Sivasubbu, S. (2024) Forward genetic screen using a gene-breaking trap approach identifies a novel role of grin2bb-associated RNA transcript (grin2bbART) in zebrafish heart function. Frontiers in cell and developmental biology. 12:13392921339292

Anzell, A.R., Kunz, A.B., Donovan, J.P., Tran, T.G., Lu, X., Young, S., Roman, B.L. (2024) Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity. Angiogenesis. 27(3):501-522

da Silva, A.R., Gunawan, F., Boezio, G.L.M., Faure, E., Théron, A., Avierinos, J.F., Lim, S., Jha, S.G., Ramadass, R., Guenther, S., Looso, M., Zaffran, S., Juan, T., Stainier, D.Y.R. (2024) egr3 is a mechanosensitive transcription factor gene required for cardiac valve morphogenesis. Science advances. 10:eadl0633

Hu, T., Liu, L., Wang, H., Yang, M., Xu, B., Xie, H., Lin, Z., Jin, X., Wang, P., Liu, Y., Sun, H., Liu, S. (2024) RCAN family member 3 deficiency contributes to noncompaction of the ventricular myocardium. Journal of genetics and genomics = Yi chuan xue bao. 51(5):543-553

Juan, T., Bellec, M., Cardoso, B., Athéa, H., Fukuda, N., Albu, M., Günther, S., Looso, M., Stainier, D.Y.R. (2024) Control of cardiac contractions using Cre-lox and degron strategies in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 121:e2309842121e2309842121

Liang, S., Zhou, Y., Chang, Y., Li, J., Zhang, M., Gao, P., Li, Q., Yu, H., Kawakami, K., Ma, J., Zhang, R. (2024) A novel gene-trap line reveals the dynamic patterns and essential roles of cysteine and glycine-rich protein 3 in zebrafish heart development and regeneration. Cellular and molecular life sciences : CMLS. 81:158158

Schumacher, J.A., Wright, Z.A., Rufin Florat, D., Anand, S.K., Dasyani, M., Batta, S.P.R., Laverde, V., Ferrari, K., Klimkaite, L., Bredemeier, N.O., Gurung, S., Koller, G.M., Aguera, K.N., Chadwick, G.P., Johnson, R.D., Davis, G.E., Sumanas, S. (2024) SH2 domain protein E and ABL signaling regulate blood vessel size. PLoS Genetics. 20:e1010851e1010851

Yu, C., Li, X., Ma, J., Liang, S., Zhao, Y., Li, Q., Zhang, R. (2024) Spatiotemporal modulation of nitric oxide and Notch signaling by hemodynamic-responsive Trpv4 is essential for ventricle regeneration. Cellular and molecular life sciences : CMLS. 81:6060

Zhou, Z.Y., Ma, J., Zhao, W.R., Shi, W.T., Zhang, J., Hu, Y.Y., Yue, M.Y., Zhou, W.L., Yan, H., Tang, J.Y., Wang, Y. (2024) Qiangxinyin formula protects against isoproterenol-induced cardiac hypertrophy. Phytomedicine : international journal of phytotherapy and phytopharmacology. 130:155717155717

Auman, H.J., Fernandes, I.H., Berríos-Otero, C.A., Colombo, S., Yelon, D. (2023) Zebrafish smarcc1a mutants reveal requirements for BAF chromatin remodeling complexes in distinguishing the atrioventricular canal from the cardiac chambers. Developmental Dynamics : an official publication of the American Association of Anatomists. 253(1):157-172

Bradshaw, M., Squire, J.M., Morris, E., Atkinson, G., Richardson, R., Lees, J., Caputo, M., Bigotti, G.M., Paul, D.M. (2023) Zebrafish as a model for cardiac disease; Cryo-EM structure of native cardiac thin filaments from Danio Rerio. Journal of muscle research and cell motility. 44(3):179-192

Cai, W., Wang, Y., Luo, Y., Gao, L., Zhang, J., Jiang, Z., Fan, X., Li, F., Xie, Y., Wu, X., Li, Y., Yuan, W. (2023) asb5a/asb5b Double Knockout Affects Zebrafish Cardiac Contractile Function. International Journal of Molecular Sciences. 24(22):

Canham, L., Sendac, S., Diagbouga, M.R., Wolodimeroff, E., Pirri, D., Tardajos Ayllon, B., Feng, S., Souilhol, C., Chico, T.J.A., Evans, P.C., Serbanovic-Canic, J. (2023) EVA1A (Eva-1 Homolog A) Promotes Endothelial Apoptosis and Inflammatory Activation Under Disturbed Flow Via Regulation of Autophagy. Arteriosclerosis, Thrombosis, and Vascular Biology. 43(4):547-561

Hofeichner, J., Gahr, B.M., Huber, M., Boos, A., Rottbauer, W., Just, S. (2023) CRISPR/Cas9-mediated nexilin deficiency interferes with cardiac contractile function in zebrafish in vivo. Scientific Reports. 13:2267922679

Jia, B.Z., Qi, Y., Wong-Campos, J.D., Megason, S.G., Cohen, A.E. (2023) A bioelectrical phase transition patterns the first vertebrate heartbeats. Nature. 622(7981):149-155

Juan, T., Ribeiro da Silva, A., Cardoso, B., Lim, S., Charteau, V., Stainier, D.Y.R. (2023) Multiple pkd and piezo gene family members are required for atrioventricular valve formation. Nature communications. 14:214214

Li, H., Luo, Q., Cai, S., Tie, R., Meng, Y., Shan, W., Xu, Y., Zeng, X., Qian, P., Huang, H. (2023) Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells. Stem Cell Research & Therapy. 14:117117

Nguyen, P.D., Gooijers, I., Campostrini, G., Verkerk, A.O., Honkoop, H., Bouwman, M., de Bakker, D.E.M., Koopmans, T., Vink, A., Lamers, G.E.M., Shakked, A., Mars, J., Mulder, A.A., Chocron, S., Bartscherer, K., Tzahor, E., Mummery, C.L., de Boer, T.P., Bellin, M., Bakkers, J. (2023) Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration. Science (New York, N.Y.). 380:758764758-764

Singh Angom, R., Wang, Y., Wang, E., Dutta, S., Mukhopadhyay, D. (2023) Conditional, Tissue-Specific CRISPR/Cas9 Vector System in Zebrafish Reveals the Role of Nrp1b in Heart Regeneration. Arteriosclerosis, Thrombosis, and Vascular Biology. 43(10):1921-1934

Coxam, B., Collins, R.T., Hußmann, M., Huisman, Y., Meier, K., Jung, S., Bartels-Klein, E., Szymborska, A., Finotto, L., Helker, C.S.M., Stainier, D.Y.R., Schulte-Merker, S., Gerhardt, H. (2022) Svep1 stabilizes developmental vascular anastomosis in reduced flow conditions. Development (Cambridge, England). 149(6):

Dong, X., Jiang, D., Wang, L., Zhao, J., Yu, L., Huang, Y., Wu, X., Zhu, Y., Zhao, Y., Zhao, Q., Zhang, G., Li, X. (2022) VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion. iScience. 25:104042

El-Sammak, H., Yang, B., Guenther, S., Chen, W., Marín-Juez, R., Stainier, D.Y.R. (2022) A Vegfc-Emilin2a-Cxcl8a Signaling Axis Required for Zebrafish Cardiac Regeneration. Circulation research. 130(7):1014-1029

Halabi, R., Cechmanek, P.B., Hehr, C.L., McFarlane, S. (2022) Semaphorin3f as a cardiomyocyte derived regulator of heart chamber development. Cell communication and signaling : CCS. 20:126

Kugler, E.C., Frost, J., Silva, V., Plant, K., Chhabria, K., Chico, T.J.A., Armitage, P.A. (2022) Zebrafish Vascular Quantification (ZVQ): a tool for quantification of three-dimensional zebrafish cerebrovascular architecture by automated image analysis. Development (Cambridge, England). 149(3):

Lai, H.H., Yeh, K.Y., Hsu, H.M., Her, G.M. (2022) Deficiency of Adipose Triglyceride Lipase Induces Metabolic Syndrome and Cardiomyopathy in Zebrafish. International Journal of Molecular Sciences. 24(1):

Metikala, S., Warkala, M., Casie Chetty, S., Chestnut, B., Rufin Florat, D., Plender, E., Nester, O., Koenig, A.L., Astrof, S., Sumanas, S. (2022) Integration of vascular progenitors into functional blood vessels represents a distinct mechanism of vascular growth. Developmental Cell. 57(6):767-782.e6

Salgado-Almario, J., Vicente, M., Molina, Y., Martinez-Sielva, A., Vincent, P., Domingo, B., Llopis, J. (2022) Simultaneous imaging of calcium and contraction in the beating heart of zebrafish larvae. Theranostics. 12:1012-1029

Song, M., Yuan, X., Racioppi, C., Leslie, M., Stutt, N., Aleksandrova, A., Christiaen, L., Wilson, M.D., Scott, I.C. (2022) GATA4/5/6 family transcription factors are conserved determinants of cardiac versus pharyngeal mesoderm fate. Science advances. 8:eabg0834

Vicente, M., Salgado-Almario, J., Valiente-Gabioud, A.A., Collins, M.M., Vincent, P., Domingo, B., Llopis, J. (2022) Early calcium and cardiac contraction defects in a model of phospholamban R9C mutation in zebrafish. Journal of Molecular and Cellular Cardiology. 173:127-140

Vignes, H., Vagena-Pantoula, C., Prakash, M., Fukui, H., Norden, C., Mochizuki, N., Jug, F., Vermot, J. (2022) Extracellular mechanical forces drive endocardial cell volume decrease during zebrafish cardiac valve morphogenesis. Developmental Cell. 57(5):598-609.e5

Xu, C., Ou, E., Li, Z., Chen, Z., Jia, Q., Xu, X., Luo, L., Xu, G., Liu, J., Yuan, Z., Zhao, Y. (2022) Synthesis and in vivo evaluation of new steviol derivatives that protect against cardiomyopathy by inhibiting ferroptosis. Bioorganic chemistry. 129:106142

Derrick, C.J., Pollitt, E.J.G., Sevilla Uruchurtu, A.S., Hussein, F., Grierson, A.J., Noël, E.S. (2021) Lamb1a regulates atrial growth by limiting second heart field addition during zebrafish heart development. Development (Cambridge, England). 148(20)

Dhakal, S., Rotem-Bamberger, S., Sejd, J.R., Sebbagh, M., Ronin, N., Frey, R.A., Beitsch, M., Batty, M., Taler, K., Blackerby, J.F., Inbal, A., Stenkamp, D.L. (2021) Selective Requirements for Vascular Endothelial Cells and Circulating Factors in the Regulation of Retinal Neurogenesis. Frontiers in cell and developmental biology. 9:628737

Djenoune, L., Tomar, R., Dorison, A., Ghobrial, I., Schenk, H., Hegermann, J., Beverly-Staggs, L., Hidalgo-Gonzalez, A., Little, M.H., Drummond, I.A. (2021) Autonomous Calcium Signaling in Human and Zebrafish Podocytes Controls Kidney Filtration Barrier Morphogenesis. Journal of the American Society of Nephrology : JASN. 32(7):1697-1712

Fan, E., Xu, Z., Yan, J., Wang, F., Sun, S., Zhang, Y., Zheng, S., Wang, X., Rao, Y. (2021) Acute exposure to N-Ethylpentylone induces developmental toxicity and dopaminergic receptor-regulated aberrances in zebrafish larvae. Toxicology and applied pharmacology. 417:115477

Fukui, H., Chow, R.W., Xie, J., Foo, Y.Y., Yap, C.H., Minc, N., Mochizuki, N., Vermot, J. (2021) Bioelectric signaling and the control of cardiac cell identity in response to mechanical forces. Science (New York, N.Y.). 374:351-354

Geng, F., Ma, J., Li, X., Hu, Z., Zhang, R. (2021) Hemodynamic Forces Regulate Cardiac Regeneration-Responsive Enhancer Activity during Ventricle Regeneration. International Journal of Molecular Sciences. 22(8):

Gentile, A., Bensimon-Brito, A., Priya, R., Maischein, H.M., Piesker, J., Guenther, S., Gunawan, F., Stainier, D.Y. (2021) The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression. eLIFE. 10:

Haege, E.R., Huang, H.C., Huang, C.C. (2021) Identification of Lactate as a Cardiac Protectant by Inhibiting Inflammation and Cardiac Hypertrophy Using a Zebrafish Acute Heart Failure Model. Pharmaceuticals (Basel, Switzerland). 14(3):

Hunter, M.V., Moncada, R., Weiss, J.M., Yanai, I., White, R.M. (2021) Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface. Nature communications. 12:6278

Jeong, Y.M., Lee, J.G., Cho, H.J., Lee, W.S., Jeong, J., Lee, J.S. (2021) Differential Clearance of Aβ Species from the Brain by Brain Lymphatic Endothelial Cells in Zebrafish. International Journal of Molecular Sciences. 22(21):

Kamel, S.M., Koopman, C.D., Kruse, F., Willekers, S., Chocron, S., Bakkers, J. (2021) A Heterozygous Mutation in Cardiac Troponin T Promotes Ca²⁺ Dysregulation and Adult Cardiomyopathy in Zebrafish. Journal of cardiovascular development and disease. 8(4):

Kamel, S.M., van Opbergen, C.J.M., Koopman, C.D., Verkerk, A.O., Boukens, B.J.D., de Jonge, B., Onderwater, Y.L., van Alebeek, E., Chocron, S., Polidoro Pontalti, C., Weuring, W.J., Vos, M.A., de Boer, T.P., van Veen, T.A.B., Bakkers, J. (2021) Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model of phospholamban R14del cardiomyopathy. Nature communications. 12:7151

Koopman, C.D., De Angelis, J., Iyer, S.P., Verkerk, A.O., Da Silva, J., Berecki, G., Jeanes, A., Baillie, G.J., Paterson, S., Uribe, V., Ehrlich, O.V., Robinson, S.D., Garric, L., Petrou, S., Simons, C., Vetter, I., Hogan, B.M., de Boer, T.P., Bakkers, J., Smith, K.A. (2021) The zebrafish grime mutant uncovers an evolutionarily conserved role for Tmem161b in the control of cardiac rhythm. Proceedings of the National Academy of Sciences of the United States of America. 118(9):

Kugler, E., Snodgrass, R., Bowley, G., Plant, K., Serbanovic-Canic, J., Hamilton, N., Evans, P.C., Chico, T., Armitage, P. (2021) The effect of absent blood flow on the zebrafish cerebral and trunk vasculature. Vascular biology (Bristol, England). 3:1-16

Li, W., Tran, V., Shaked, I., Xue, B., Moore, T., Lightle, R., Kleinfeld, D., Awad, I.A., Ginsberg, M.H. (2021) Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations. eLIFE. 10:

Paolini, A., Fontana, F., Pham, V.C., Rödel, C.J., Abdelilah-Seyfried, S. (2021) Mechanosensitive Notch-Dll4 and Klf2-Wnt9 signaling pathways intersect in guiding valvulogenesis in zebrafish. Cell Reports. 37:109782

Parvez, S., Herdman, C., Beerens, M., Chakraborti, K., Harmer, Z.P., Yeh, J.J., MacRae, C.A., Yost, H.J., Peterson, R.T. (2021) MIC-Drop: A platform for large-scale in vivo CRISPR screens. Science (New York, N.Y.). 373(6559):1146-1151

Ranawat, N., Masai, I. (2021) Mechanisms underlying microglial colonization of developing neural retina in zebrafish. eLIFE. 10:

Takashima, S., Takemoto, S., Toyoshi, K., Ohba, A., Shimozawa, N. (2021) Zebrafish model of human Zellweger syndrome reveals organ-specific accumulation of distinct fatty acid species and widespread gene expression changes. Molecular genetics and metabolism. 133(3):307-323

Tessadori, F., Tsingos, E., Colizzi, E.S., Kruse, F., van den Brink, S.C., van den Boogaard, M., Christoffels, V.M., Merks, R.M., Bakkers, J. (2021) Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process. eLIFE. 10:

Tsao, K.C., Lin, Y.C., Chen, Y.T., Lai, S.L., Yang, R.B. (2021) Zebrafish scube1 and scube2 cooperate in promoting Vegfa signaling during embryonic vascularization. Cardiovascular research. 118(4):1074-1087

Vicente, M., Salgado-Almario, J., Collins, M.M., Martínez-Sielva, A., Minoshima, M., Kikuchi, K., Domingo, B., Llopis, J. (2021) Cardioluminescence in Transgenic Zebrafish Larvae: A Calcium Imaging Tool to Study Drug Effects and Pathological Modeling. Biomedicines. 9(10):

Wang, Y., Pasparakis, C., Grosell, M. (2021) Role of the cardiovascular system in ammonia excretion in early life stages of zebrafish (Danio rerio). American journal of physiology. Regulatory, integrative and comparative physiology. 321(3):R377-R384

Watterston, C., Halabi, R., McFarlane, S., Childs, S.J. (2021) Endothelial Semaphorin 3fb regulates Vegf pathway-mediated angiogenic sprouting. PLoS Genetics. 17:e1009769

Wen, L., Zhang, T., Wang, J., Jin, X., Rouf, M.A., Luo, D., Zhu, Y., Lei, D., Gregersen, H., Wang, Y., Wang, G. (2021) The blood flow-klf6a-tagln2 axis drives vessel pruning in zebrafish by regulating endothelial cell rearrangement and actin cytoskeleton dynamics. PLoS Genetics. 17:e1009690

Yue, M.S., Martin, S.E., Martin, N.R., Taylor, M.R., Plavicki, J.S. (2021) 2,3,7,8-Tetrachlorodibenzo-p-dioxin exposure disrupts development of the visceral and ocular vasculature. Aquatic toxicology (Amsterdam, Netherlands). 234:105786

Zhang, H., Liu, B., Xu, G., Xu, C., Ou, E., Liu, J., Sun, X., Zhao, Y. (2021) Synthesis and in vivo screening of isosteviol derivatives as new cardioprotective agents. European Journal of Medicinal Chemistry. 219:113396

Zheng, N., Yan, J., Qian, W., Song, C., Zuo, Z., He, C. (2021) Comparison of developmental toxicity of different surface modified CdSe/ZnS QDs in zebrafish embryos. Journal of environmental sciences (China). 100:240-249

Bautista, N.M., Crespel, A., Crossley, J., Padilla, P., Burggren, W. (2020) Parental transgenerational epigenetic inheritance related to dietary crude oil exposure in Danio rerio. The Journal of experimental biology. 223(Pt 16):

Campinho, P., Lamperti, P., Boselli, F., Vilfan, A., Vermot, J. (2020) Blood Flow Limits Endothelial Cell Extrusion in the Zebrafish Dorsal Aorta. Cell Reports. 31:107505

Christou, M., Fraser, T.W.K., Berg, V., Ropstad, E., Kamstra, J.H. (2020) Calcium signaling as a possible mechanism behind increased locomotor response in zebrafish larvae exposed to a human relevant persistent organic pollutant mixture or PFOS. Environmental research. 187:109702

Cunha, V., Vogs, C., Le Bihanic, F., Dreij, K. (2020) Mixture effects of oxygenated PAHs and benzo[a]pyrene on cardiovascular development and function in zebrafish embryos. Environment International. 143:105913

Demin, K.A., Lakstygal, A.M., Krotova, N.A., Masharsky, A., Tagawa, N., Chernysh, M.V., Ilyin, N.P., Taranov, A.S., Galstyan, D.S., Derzhavina, K.A., Levchenko, N.A., Kolesnikova, T.O., Mor, M.S., Vasyutina, M.L., Efimova, E.V., Katolikova, N., Prjibelski, A.D., Gainetdinov, R.R., de Abreu, M.S., Amstislavskaya, T.G., Strekalova, T., Kalueff, A.V. (2020) Understanding complex dynamics of behavioral, neurochemical and transcriptomic changes induced by prolonged chronic unpredictable stress in zebrafish. Scientific Reports. 10:19981

Fang, Y., Lai, K.S., She, P., Sun, J., Tao, W., Zhong, T.P. (2020) Tbx20 Induction Promotes Zebrafish Heart Regeneration by Inducing Cardiomyocyte Dedifferentiation and Endocardial Expansion. Frontiers in cell and developmental biology. 8:738

Faucherre, A., Maati, H.M.O., Nasr, N., Pinard, A., Theron, A., Odelin, G., Desvignes, J.P., Salgado, D., Collod-Béroud, G., Avierinos, J.F., Lebon, G., Zaffran, S., Jopling, C. (2020) Piezo1 and outflow tract and aortic valve development. Journal of Molecular and Cellular Cardiology. 143:51-62

Fontana, F., Haack, T., Reichenbach, M., Knaus, P., Puceat, M., Abdelilah-Seyfried, S. (2020) Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis. Cell Reports. 32:107883

Han, C.R., Wang, H., Hoffmann, V., Zerfas, P., Kruhlak, M., Cheng, S.Y. (2020) Thyroid hormone receptor α mutations cause heart defects in zebrafish. Thyroid : official journal of the American Thyroid Association. 31(2):315-326

Kim, C., Choe, H., Park, J., Kim, G., Kim, K., Jeon, H.J., Moon, J.K., Kim, M.J., Lee, S.E. (2020) Molecular mechanisms of developmental toxicities of azoxystrobin and pyraclostrobin toward zebrafish (Danio rerio) embryos: Visualization of abnormal development using two transgenic lines. Environmental pollution (Barking, Essex : 1987). 270:116087

Kim, Y.C., Lee, S.R., Jeon, H.J., Kim, K., Kim, M.J., Choi, S.D., Lee, S.E. (2020) Acute toxicities of fluorene, fluorene-1-carboxylic acid, and fluorene-9-carboxylic acid on zebrafish embryos (Danio rerio): Molecular mechanisms of developmental toxicities of fluorene-1-carboxylic acid. Chemosphere. 260:127622

Klems, A., van Rijssel, J., Ramms, A.S., Wild, R., Hammer, J., Merkel, M., Derenbach, L., Préau, L., Hinkel, R., Suarez-Martinez, I., Schulte-Merker, S., Vidal, R., Sauer, S., Kivelä, R., Alitalo, K., Kupatt, C., van Buul, J.D., le Noble, F. (2020) The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models. Nature communications. 11:5319

Lundin, V., Sugden, W.W., Theodore, L.N., Sousa, P.M., Han, A., Chou, S., Wrighton, P.J., Cox, A.G., Ingber, D.E., Goessling, W., Daley, G.Q., North, T.E. (2020) YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow. Developmental Cell. 52(4):446-460.e5

Mu, X., Chen, X., Liu, J., Yuan, L., Wang, D., Qian, L., Qian, Y., Shen, G., Huang, Y., Li, X., Li, Y., Lin, X. (2020) A multi-omics approach reveals molecular mechanisms by which phthalates induce cardiac defects in zebrafish (Danio rerio). Environmental pollution (Barking, Essex : 1987). 265:113876

Ni, J., Wang, H., Wei, X., Shen, K., Sha, Y., Dong, Y., Shu, Y., Wan, X., Cheng, J., Wang, F., Liu, Y. (2020) Isoniazid causes heart looping disorder in zebrafish embryos by the induction of oxidative stress. BMC pharmacology & toxicology. 21:22

Priya, R., Allanki, S., Gentile, A., Mansingh, S., Uribe, V., Maischein, H.M., Stainier, D.Y.R. (2020) Tension heterogeneity directs form and fate to pattern the myocardial wall. Nature. 588(7836):130-134

Sidhwani, P., Leerberg, D.M., Boezio, G.L.M., Capasso, T.L., Yang, H., Chi, N.C., Roman, B.L., Stainier, D.Y.R., Yelon, D. (2020) Cardiac function modulates endocardial cell dynamics to shape the cardiac outflow tract. Development (Cambridge, England). 147(12):

Tang, C., Shen, C., Zhu, K., Zhou, Y., Chuang, Y.J., He, C., Zuo, Z. (2020) Exposure to the AhR agonist cyprodinil impacts the cardiac development and function of zebrafish larvae. Ecotoxicology and environmental safety. 201:110808

Yang, L., Jiménez, J.A., Earley, A.M., Hamlin, V., Kwon, V., Dixon, C.T., Shiau, C.E. (2020) Drainage of inflammatory macromolecules from brain to periphery targets the liver for macrophage infiltration. eLIFE. 9:

Andrés-Delgado, L., Ernst, A., Galardi-Castilla, M., Bazaga, D., Peralta, M., Münch, J., González-Rosa, J.M., Marques, I., Tessadori, F., de la Pompa, J.L., Vermot, J., Mercader, N. (2019) Actin dynamics and the Bmp pathway drive apical extrusion of proepicardial cells. Development (Cambridge, England). 146(13):

Denis, J.F., Diagbouga, M.R., Molica, F., Hautefort, A., Linnerz, T., Watanabe, M., Lemeille, S., Bertrand, J.Y., Kwak, B.R. (2019) KLF4-Induced Connexin40 Expression Contributes to Arterial Endothelial Quiescence. Frontiers in Physiology. 10:80

Duchemin, A.L., Vignes, H., Vermot, J. (2019) Mechanically activated Piezo channels modulate outflow tract valve development through the Yap1 and Klf2-Notch signaling axis. eLIFE. 8:

Fukuda, R., Gunawan, F., Ramadass, R., Beisaw, A., Konzer, A., Mullapudi, S.T., Gentile, A., Maischein, H.M., Graumann, J., Stainier, D.Y.R. (2019) Mechanical Forces Regulate Cardiomyocyte Myofilament Maturation via the VCL-SSH1-CFL Axis. Developmental Cell. 51(1):62-77.e5

Honkoop, H., de Bakker, D.E., Aharonov, A., Kruse, F., Shakked, A., Nguyen, P.D., de Heus, C., Garric, L., Muraro, M.J., Shoffner, A., Tessadori, F., Peterson, J.C., Noort, W., Bertozzi, A., Weidinger, G., Posthuma, G., Grun, D., van der Laarse, W.J., Klumperman, J., Jaspers, R.T., Poss, K.D., van Oudenaarden, A., Tzahor, E., Bakkers, J. (2019) Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart. eLIFE. 8:

Hsu, J.J., Vedula, V., Baek, K.I., Chen, C., Chen, J., Chou, M.I., Lam, J., Subhedar, S., Wang, J., Ding, Y., Chang, C.C., Lee, J., Demer, L.L., Tintut, Y., Marsden, A.L., Hsiai, T.K. (2019) Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation. JCI insight. 5(10):

Hughes, M.C., Zimmer, A.M., Perry, S.F. (2019) The role of internal convection in respiratory gas transfer and aerobic metabolism in larval zebrafish ( Danio rerio). American journal of physiology. Regulatory, integrative and comparative physiology. 316(3):R255-R264

Jiménez-Amilburu, V., Stainier, D.Y.R. (2019) The transmembrane protein Crb2a regulates cardiomyocyte apicobasal polarity and adhesion in zebrafish. Development (Cambridge, England). 146(9):

Kugler, E.C., van Lessen, M., Daetwyler, S., Chhabria, K., Savage, A.M., Silva, V., Plant, K., MacDonald, R.B., Huisken, J., Wilkinson, R.N., Schulte-Merker, S., Armitage, P., Chico, T.J. (2019) Cerebrovascular endothelial cells form transient Notch-dependent cystic structures in zebrafish. EMBO reports. 20:e47047

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Cvejic, A., Serbanovic-Canic, J., Stemple, D.L., and Ouwehand, W.H. (2011) The Role Of Meis1 In Primitive And Definitive Hematopoiesis During Zebrafish Development. Haematologica. 96(2):190-198

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Herwig, L., Blum, Y., Krudewig, A., Ellertsdottir, E., Lenard, A., and Belting, H.G., and Affolter, M. (2011) Distinct Cellular Mechanisms of Blood Vessel Fusion in the Zebrafish Embryo. Current biology : CB. 21(22):1942-1948

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Additional Citations (30):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

Zebrafish Nomenclature Committee (2023) Nomenclature Data Curation (2023). Nomenclature Committee Submission.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

Geisler, R. (2013) Importation of Tübingen internal allele names. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

Ekker, S., Clark, K., ZFIN Staff (2012) Curation of zfishbook links. ZFIN Direct Data Submission.

ZFIN Database Team (2012) Linkage Group (LG) to Chromosome (Chr). Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

Phenotype Annotation (1994-2006) (2006) Mutant Data Curated from Older Literature. ZFIN Historical Data.

ZFIN Staff (2006) Curation of SNP Database Links. Automated Data Submission.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, C., and Thisse, B. (2005) High Throughput Expression Analysis of ZF-Models Consortium Clones. ZFIN Direct Data Submission.

ZFIN Staff (2004) Gene Ontology Annotation Inferred from Orthology. Manually curated data.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.

ZFIN Staff (2003) Submission and Curation of Mutant and Transgenic Lines. ZFIN Direct Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.

Sehnert, A. (2002) Direct Submission of Mapping Data (Amy Sehnert). Direct Submission of Mapping Data.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.