ZFIN ID: ZDB-FIG-200423-61
Zhu et al., 2020 - Functional Characterization and Expression Analyses Show Differential Roles of Maternal and Zygotic Dgcr8 in Early Embryonic Development. Frontiers in genetics   11:299 Full text @ Front Genet
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Term:
Stage Range: 30%-epiboly to Prim-15
PHENOTYPE:
Fish:
Observed In:
Stage Range: 30%-epiboly to Prim-15

FIGURE 7

mRNA expression variation in wild-type and MZdgcr8 embryos during 30% epiboly stage. (A) Top 30 downregulated genes from RNA-seq data. (B) Top 30 upregulated genes from RNA-seq data. (C) Expression count of miRNAs biogenesis related genes.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
abcd3a dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
acadl dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
ago2 WT standard conditions Prim-15 whole organism RNA-Seq
dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
akr1b1.2 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
amt dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
bicc1a dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
buc dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
cd82b dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
ddx1 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
dgcr8 WT standard conditions Prim-15 whole organism RNA-Seq
dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
dicer1 WT standard conditions Prim-15 whole organism RNA-Seq
dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
dnajc5ga dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
dnm1l dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
dock4b dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
eif4ebp2 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
foxd3 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
hnrnpa0a dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
hsp70.3 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
hsp90aa1.2 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
itgam.1 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly Not Detected whole organism RNA-Seq
ly75 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
mt-nd6 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
mtus1a dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
ndrg1b dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
opa1 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
phc2b dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
pho dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
plcb3 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
ppt2a.4 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
drosha WT standard conditions Prim-15 whole organism RNA-Seq
dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
sbf2 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
selenoh dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly Not Detected whole organism RNA-Seq
sh2d5 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
si:ch211-209p16.1 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
si:ch211-259g3.4 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
si:ch211-263m18.4 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
si:ch1073-190k2.1 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
si:ch1073-263o8.2 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
si:dkey-19a16.7 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
si:dkey-21a6.5 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
si:dkey-29j8.3 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly Not Detected whole organism RNA-Seq
si:dkey-119f1.1 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
si:dkey-122c11.4 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
si:dkey-156k2.3 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
akap13 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
smarca2 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
tdrd1 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
tdrd6 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
xpo5 WT standard conditions Prim-15 whole organism RNA-Seq
dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
zgc:113208 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
zgc:152891 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
zgc:163014 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions Prim-15 whole organism RNA-Seq
zgc:171776 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
znf997 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
znf1031 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
znf1053 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
znf1063 dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism RNA-Seq
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
dgcr8zf1064/zf1064; ihb7Tg; zf1065Tg standard conditions 30%-epiboly whole organism hnrnpa0a expression decreased amount, abnormal
30%-epiboly whole organism hsp70.3 expression decreased amount, abnormal
30%-epiboly whole organism hsp90aa1.2 expression decreased amount, abnormal
30%-epiboly whole organism itgam.1 expression absent, abnormal
30%-epiboly whole organism mt-nd6 expression decreased amount, abnormal
30%-epiboly whole organism ndrg1b expression decreased amount, abnormal
30%-epiboly whole organism pho expression decreased amount, abnormal
30%-epiboly whole organism ppt2a.4 expression decreased amount, abnormal
30%-epiboly whole organism selenoh expression absent, abnormal
30%-epiboly whole organism si:ch1073-190k2.1 expression decreased amount, abnormal
30%-epiboly whole organism si:ch1073-263o8.2 expression decreased amount, abnormal
30%-epiboly whole organism si:ch211-209p16.1 expression decreased amount, abnormal
30%-epiboly whole organism si:ch211-263m18.4 expression decreased amount, abnormal
30%-epiboly whole organism si:dkey-122c11.4 expression decreased amount, abnormal
30%-epiboly whole organism si:dkey-156k2.3 expression decreased amount, abnormal
30%-epiboly whole organism si:dkey-19a16.7 expression decreased amount, abnormal
30%-epiboly whole organism si:dkey-29j8.3 expression absent, abnormal
30%-epiboly whole organism zgc:113208 expression decreased amount, abnormal
30%-epiboly whole organism zgc:171776 expression decreased amount, abnormal
30%-epiboly whole organism znf1031 expression decreased amount, abnormal
30%-epiboly whole organism znf1053 expression decreased amount, abnormal
30%-epiboly whole organism znf1063 expression decreased amount, abnormal
30%-epiboly whole organism znf997 expression decreased amount, abnormal
Prim-15 whole organism abcd3a expression increased amount, abnormal
Prim-15 whole organism acadl expression increased amount, abnormal
Prim-15 whole organism ago2 expression increased amount, abnormal
Prim-15 whole organism akap13 expression increased amount, abnormal
Prim-15 whole organism akr1b1.2 expression increased amount, abnormal
Prim-15 whole organism amt expression increased amount, abnormal
Prim-15 whole organism bicc1a expression increased amount, abnormal
Prim-15 whole organism buc expression increased amount, abnormal
Prim-15 whole organism cd82b expression increased amount, abnormal
Prim-15 whole organism ddx1 expression increased amount, abnormal
Prim-15 whole organism dicer1 expression increased amount, abnormal
Prim-15 whole organism dnajc5ga expression increased amount, abnormal
Prim-15 whole organism dnm1l expression increased amount, abnormal
Prim-15 whole organism dock4b expression increased amount, abnormal
Prim-15 whole organism eif4ebp2 expression increased amount, abnormal
Prim-15 whole organism foxd3 expression increased amount, abnormal
Prim-15 whole organism ly75 expression increased amount, abnormal
Prim-15 whole organism mtus1a expression increased amount, abnormal
Prim-15 whole organism opa1 expression increased amount, abnormal
Prim-15 whole organism phc2b expression increased amount, abnormal
Prim-15 whole organism plcb3 expression increased amount, abnormal
Prim-15 whole organism sbf2 expression increased amount, abnormal
Prim-15 whole organism sh2d5 expression increased amount, abnormal
Prim-15 whole organism si:ch211-259g3.4 expression increased amount, abnormal
Prim-15 whole organism si:dkey-119f1.1 expression increased amount, abnormal
Prim-15 whole organism si:dkey-21a6.5 expression increased amount, abnormal
Prim-15 whole organism smarca2 expression increased amount, abnormal
Prim-15 whole organism tdrd1 expression increased amount, abnormal
Prim-15 whole organism tdrd6 expression increased amount, abnormal
Prim-15 whole organism zgc:152891 expression increased amount, abnormal
Prim-15 whole organism zgc:163014 expression increased amount, abnormal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Genet