ZFIN ID: ZDB-GENE-060130-74
Gene Name: dedicator of cytokinesis 4b
Gene Symbol: dock4b    Nomenclature History

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Previous Names: sb:eu488 (1), si:ch211-284e3.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have GTPase activator activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Orthologous to human DOCK4 (dedicator of cytokinesis 4).
Genome Resources: Alliance (1),  Gene:654774 (1),  Ensembl(GRCz11):ENSDARG00000024874 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu488]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la024729Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la024730Tg Transgenic Insertion Unknown Unknown DNA
    sa12293 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14015 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15932 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16113 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16345 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17211 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20201 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20202 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33381 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa40222 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dock4b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dock4b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process small GTPase mediated signal transduction (more)
    Molecular Function GTPase activator activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dock4b-203 (1)    Ensembl 5451
    ncRNA dock4b-002 (1)    Ensembl 680
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dock4b No data available
    MARKER RELATIONSHIPS
    dock4b Contained in: [BAC] CH73-238A11 (1), CH211-284E3 (1)
    dock4b Encodes: [EST] eu488 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001166228 (1) 6111 nt
    Genomic GenBank:CR388190 (1) 143462 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IEH3 (1) 1993 aa
    Sequence Information (all 27)
    ORTHOLOGY for dock4b ( Chr: 4 )
    CITATIONS (19)