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ZIRC
ZFIN ID: ZDB-GENE-030131-3445
Gene Name: dicer 1, ribonuclease type III
Gene Symbol: dicer1
Sequence Ontology ID : SO:0000704

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Previous Names: fc39d11, fc74b05, wu:fc39d11, wu:fc74b05

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits pre-miRNA binding activity. Involved in gene silencing by miRNA and nervous system development. Predicted to localize to several cellular components, including the RISC complex; RISC-loading  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu715 Point Mutation Unknown Premature Stop ENU
hu894 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hu896 Point Mutation Unknown Premature Stop ENU
    sa9205 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11548 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19169 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH dicer1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    multinodular goiter Goiter, multinodular 1, with or without Sertoli-Leydig cell tumors 138800
    pleuropulmonary blastoma Pleuropulmonary blastoma 601200
    Rhabdomyosarcoma, embryonal, 2 180295
    GLOW syndrome, somatic mosaic 618272
    DISEASE ASSOCIATED WITH dicer1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mRNA cleavage involved in gene silencing by miRNA (more)
    Cellular Component RISC complex (more)
    Molecular Function pre-miRNA binding (more)
    GO Terms (all 28)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA dicer1-201 (1) 9598
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM dicer1 No data available
    MARKER RELATIONSHIPS
    dicer1Contained in: [BAC] DKEY-51K10 (1) (order this)
    dicer1Encodes: [EST] fc39d11, fc74b05 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001161453 (1)
    Genomic GenBank:AL772219 (1) 117244bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IDJ0 (1) 1905aa
    Sequence Clusters UniGene:78137 (1)
    Sequence Information (all 29)
    ORTHOLOGY for dicer1 (Chr: 17)
    CITATIONS (69)