ZFIN ID: ZDB-GENE-030616-594
Gene Name: phospholipase C, beta 3 (phosphatidylinositol-specific)
Gene Symbol: plcb3    Nomenclature History

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Previous Names: she, si:ch211-188c22.1, si:zc188c22.1, wu:fl04b08

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have calmodulin binding activity and phosphatidylinositol phospholipase C activity. Involved in negative regulation of calcium ion import; negative regulation of vascular permeability; and skeletal system development. Is expressed in several structures, including epidermis; nervous system; otic vesicle; pharyngeal arch; and pronephric duct. Orthologous to human PLCB3 (phospholipase C beta 3).
Genome Resources: Alliance (1),  Gene:100001532 (1),  Ensembl(GRCz11):ENSDARG00000068246 (2)
DISEASE ASSOCIATED WITH plcb3 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH plcb3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of calcium ion import (more)
Molecular Function calcium ion binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA plcb3-201 (1)    Ensembl 7145
ncRNA plcb3-002 (1)    Ensembl 977
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM plcb3 No data available
MARKER RELATIONSHIPS
plcb3 Contained in: [BAC] CH211-188C22 (1), DKEY-258H10 (1) (order this)
plcb3 Encodes: [EST] fl04b08, IMAGE:7154492 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001122773 (1) 3786 nt
Genomic GenBank:CR954304 (1) 165385 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IVA6 (1) 1245 aa
Sequence Information (all 23)
ORTHOLOGY for plcb3 ( Chr: 7 )
CITATIONS (35)