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ZIRC
ZFIN ID: ZDB-GENE-040426-771
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Gene Name: acyl-CoA dehydrogenase long chain
Gene Symbol: acadl    Nomenclature History

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Previous Names: LCAD (1), zgc:55656 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have flavin adenine dinucleotide binding activity; long-chain-acyl-CoA dehydrogenase activity; and palmitoyl-CoA oxidase activity. Predicted to be involved in carnitine metabolic process, CoA-linked; fatty acid beta-oxidation using acyl-CoA dehydrogenase; and long-chain fatty acid catabolic process. Predicted to localize to the mitochondrion. Is expressed in female organism. Orthologous to human ACADL (acyl-CoA dehydrogenase long chain).
Genome Resources: Alliance (1),  Gene:394156 (1),  Ensembl(GRCz11):ENSDARG00000088357 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55656]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa43157 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH acadl HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH acadl VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process long-chain fatty acid catabolic process (more)
    Cellular Component mitochondrion (more)
    Molecular Function acyl-CoA dehydrogenase activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006089 (1)
  • InterPro:IPR006091 (1)
  • InterPro:IPR009075 (1)
  • InterPro:IPR009100 (1)
  • InterPro:IPR013786 (1)
  • InterPro:IPR034179 (1)
  • InterPro:IPR036250 (1)
  • InterPro:IPR037069 (1)
  • PROSITE:PS00072 (1)
  • PROSITE:PS00073 (1)
  • Pfam:PF00441 (1)
  • Pfam:PF02770 (1)
  • Pfam:PF02771 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA acadl-201 (1)    Ensembl 1753
    Select Tool
    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acadl No data available
    MARKER RELATIONSHIPS
    acadl Contained in: [BAC] CH211-12A1 (1) (order this)
    acadl Encodes: [cDNA] MGC:55656 (1) (order this), MGC:86682 (1) (order this), MGC:192664 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201181 (1) 1759 bp
    Select Tool
    Genomic GenBank:BX927313 (1) 189797 bp
    Select Tool
    Polypeptide UniProtKB:A3KQR0 (1) 442 aa
    Select Tool
    Sequence Clusters UniGene:76592 (1)
    Sequence Information (all 19)
    ORTHOLOGY for acadl ( Chr: 18 )
    CITATIONS (26)