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ZIRC
ZFIN ID: ZDB-GENE-030131-3421
Gene Name: DGCR8 microprocessor complex subunit
Gene Symbol: dgcr8
Sequence Ontology ID : SO:0001217

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Previous Names: sb:eu827, sb:eu832, si:ch211-106a19.4, wu:fc23f08, wu:fc38f06

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to contribute to ribonuclease III activity. Predicted to be involved in primary miRNA processing. Predicted to localize to the microprocessor complex. Orthologous to human DGCR8 (DGCR8  ...
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu827]
  1 figure (1 image) from Thisse et al., 2005 [eu832]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
dgcr8_unrecovered Point Mutation Unknown Unknown ENU
fh344 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa223 Point Mutation Unknown Premature Stop ENU
    sa40420 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zf1064 Indel Exon 4 Unknown TALEN
    Targeting reagents:
    PHENOTYPE
    Data: Fig. 1 from Liu et al., 2017
    Observed in:
    DISEASE ASSOCIATED WITH dgcr8 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dgcr8 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process primary miRNA processing (more)
    Cellular Component microprocessor complex (more)
    Molecular Function heme binding (more)
    GO Terms (all 8)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA dgcr8-201 (1) 4703
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dgcr8
    MARKER RELATIONSHIPS
    dgcr8 Contained in: [BAC] CH211-106A19 (1) (order this)
    dgcr8 Encodes: [EST] bn0aa053za02 (1), eu827 (1), eu832 (1), fc23f08 (1), fc38f06
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001122749 (1) 4703 bp
    Genomic GenBank:BX088551 (1) 184417 bp
    Select Tool
    Polypeptide UniProtKB:A2BEG3 (1) 782 aa
    Sequence Clusters UniGene:78349 (1)
    Sequence Information (all 18)
    ORTHOLOGY for dgcr8 ( Chr: 5 )
    CITATIONS (28)