ZFIN ID: ZDB-GENE-040426-2868
Gene Name: ATP-binding cassette, sub-family D (ALD), member 3a
Gene Symbol: abcd3a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: fb59g09 (1), fd60b04 (1), wu:fb59g09 (1), wu:fd60b04 (1), zgc:55740 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have several functions, including ATP binding activity; long-chain fatty acid transporter activity; and protein homodimerization activity. Predicted to be involved in long-chain fatty acid import into peroxisome. Predicted to localize to integral component of membrane and peroxisome. Human ortholog(s) of this gene implicated in Zellweger syndrome and congenital bile acid synthesis defect 5. Orthologous to human ABCD3 (ATP binding cassette subfamily D member 3).
Genome Resources: Alliance (1),  Gene:406803 (1),  Ensembl(GRCz11):ENSDARG00000104085 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55740]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17682 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH abcd3a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    congenital bile acid synthesis defect 5 Alliance ?Bile acid synthesis defect, congenital, 5 616278
    DISEASE ASSOCIATED WITH abcd3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process long-chain fatty acid import into peroxisome (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATPase activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA abcd3a-201 (1)    Ensembl 2802
    ncRNA abcd3a-002 (1)    Ensembl 460
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abcd3a No data available
    MARKER RELATIONSHIPS
    abcd3a Contained in: [BAC] CH211-189O17 (1)
    abcd3a Encodes: [EST] fb59g09, fd60b04
    [cDNA] MGC:55740 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213482 (1) 2818 nt
    Genomic GenBank:BX682238 (1) 143212 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IRL4 (1) 656 aa
    Sequence Information (all 17)
    ORTHOLOGY for abcd3a ( Chr: 24 )
    CITATIONS (24)