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ZIRC
ZFIN ID: ZDB-GENE-040426-1648
Gene Name: N-myc downstream regulated 1b
Gene Symbol: ndrg1b
Sequence Ontology ID : SO:0000704

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Previous Names: ndrg1l, zgc:73047

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in regulation of T cell differentiation and thymus development. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4D.  ...
GENE EXPRESSION
All Expression Data: 10 figures from 5 publications
Directly Submitted Expression Data: 5 figures (8 images) from Thisse et al., 2004 [MGC:73047]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2849 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. 5 from Li et al., 2016
    Observed in:
    DISEASE ASSOCIATED WITH ndrg1b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Charcot-Marie-Tooth disease type 4D Charcot-Marie-Tooth disease, type 4D 601455
    DISEASE ASSOCIATED WITH ndrg1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of T cell differentiation (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004142 (1)
  • InterPro:IPR029058 (1)
  • InterPro:IPR030693 (1)
  • Pfam:PF03096 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ndrg1b-201 (1) 1778
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ndrg1b
    MARKER RELATIONSHIPS
    ndrg1bContained in: [BAC] DKEY-97I18 (1) (order this)
    ndrg1bEncodes: [cDNA] MGC:73047 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200692 (1) 1711bp
    Genomic GenBank:CR855311 (1) 161379bp
    Select Tool
    Polypeptide UniProtKB:A0A146JRF4 (1) 359aa
    Sequence Clusters UniGene:8090 (1)
    Sequence Information (all 19)
    ORTHOLOGY for ndrg1b (Chr: 16)
    CITATIONS (26)