Gene

ndrg1b

ID
ZDB-GENE-040426-1648
Name
N-myc downstream regulated 1b
Symbol
ndrg1b Nomenclature History
Previous Names
  • ndrg1l
  • zgc:73047
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Involved in regulation of T cell differentiation and thymus development. Predicted to localize to cytoplasm. Is expressed in epiphysis; optic vesicle; pro-T cell; retina; and thymus. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4D. Orthologous to human NDRG1 (N-myc downstream regulated 1).
Genome Resources
Note
None
Expression
All Expression Data
10 figures from 5 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. 5 from Li et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ndrg1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease type 4D Alliance Charcot-Marie-Tooth disease, type 4D 601455
Associated With ndrg1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004142 NDRG
Family IPR030693 Protein NDRG1
Homologous_superfamily IPR029058 Alpha/Beta hydrolase fold
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ndrg1b Mouse
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations