ZFIN ID: ZDB-GENE-031001-3
Gene Name: heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
Gene Symbol: hsp90aa1.2    Nomenclature History

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Previous Names: cb820 (1), hsp90a.2, hsp90a2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have ATP binding activity; disordered domain specific binding activity; and unfolded protein binding activity. Predicted to be involved in several processes, including cellular response to heat; protein stabilization; and response to cold. Predicted to localize to several cellular components, including myelin sheath; neuronal cell body; and perinuclear region of cytoplasm. Is expressed in several structures, including immature eye; mesoderm; musculature system; nervous system; and pericardial region. Orthologous to human HSP90AA1 (heat shock protein 90 alpha family class A member 1).
Genome Resources: Alliance (1),  Gene:565155 (1), 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
mu9 Small Deletion Exon 3 Premature Stop CRISPR
mu10 Small Deletion Exon 3 Frameshift, Premature Stop CRISPR
mu11 Indel Exon 3 Premature Stop CRISPR
sa1808 Point Mutation Unknown Missense ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-hsp90aa1.2 1
CRISPR2-hsp90aa1.2
2
MO1-hsp90aa1.1,hsp90aa1.2 N/A 1
MO1-hsp90aa1.2 N/A 3
MO2-hsp90aa1.2 N/A 1
MO3-hsp90aa1.2 N/A 1
DISEASE ASSOCIATED WITH hsp90aa1.2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH hsp90aa1.2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to antibiotic (more)
Cellular Component cytoplasm (more)
Molecular Function protein binding (more)
GO Terms (all 19)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA hsp90aa1.2-201 (1)    Ensembl 2667
ncRNA hsp90aa1.2-002 (1)    Ensembl 693
Browsers: NCBI
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM hsp90aa1.2 No data available
MARKER RELATIONSHIPS
hsp90aa1.2 Contained in: [BAC] DKEY-241L7 (1) (order this)
hsp90aa1.2 Encodes: [EST] cb820 (1) (order this)
[cDNA] MGC:195137 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001045073 (1) 2413 nt
Genomic GenBank:CR381646 (1) 183151 nt
Select Tool
Polypeptide UniProtKB:Q5RG12 (1) 734 aa
Sequence Information (all 17)
ORTHOLOGY for hsp90aa1.2 ( Chr: 20 )
CITATIONS (53)