ZFIN ID: ZDB-GENE-980526-143
Gene Name: forkhead box D3
Gene Symbol: foxd3
Sequence Ontology ID : SO:0000704

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Previous Names: fkd-6 (1), fkd6 (1), fkh6, forkhead-6, mother superior (2), zgc:111934

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 165 figures from 118 publications
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
  adaxial cell, axial mesoderm, brain, cranial ganglion (all 62) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ct110aGt Transgenic Insertion Unknown Unknown DNA
ct110aRGt Transgenic Insertion Unknown Unknown DNA
m188 Unknown Unknown Unknown ENU
sa174 Point Mutation Unknown Unknown ENU
sa20726 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • zdf10 Small Deletion Unknown Frameshift, Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-foxd3 (1), MO2-foxd3 (1), MO3-foxd3 (1), MO4-foxd3 (1)
    PHENOTYPE
    Data: 18 figures from 10 publications
    Observed in: autonomic nervous system development, basihyal cartilage, cartilage morphogenesis, ceratobranchial cartilage (all 35) expand
    DISEASE ASSOCIATED WITH foxd3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    {Autoimmune disease, susceptibility to, 1} 607836
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 21)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001766 (1)
  • InterPro:IPR011991 (1)
  • InterPro:IPR018122 (1)
  • InterPro:IPR030456 (1)
  • PROSITE:PS00657 (1)
  • PROSITE:PS00658 (1)
  • PROSITE:PS50039 (1)
  • Pfam:PF00250 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA foxd3-001 (1) 1799
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM foxd3
    Tg(foxd3:EGFP), Tg(foxd3:GFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    foxd3Contained in: [BAC] DKEY-148H10 (1) (order this)
    foxd3Encodes: [cDNA] MGC:111934 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131290 (1) 1799bp
    Genomic GenBank:BX664614 (1) 184225bp
    Select Tool
    Polypeptide UniProtKB:F1R5S7 (1) 371aa
    Sequence Clusters UniGene:75816 (1)
    Sequence Information (all 14)
    OTHER foxd3 GENE PAGES
  • Gene:30548 (1)
  • VEGA:OTTDARG00000019783 (1)
  • Ensembl(GRCz10):ENSDARG00000021032 (1)
  • ORTHOLOGY for foxd3 (Chr: 6)
    CITATIONS (221)