ZFIN ID: ZDB-GENE-000605-1
CITATIONS (368 total)
Gene Name: RUNX family transcription factor 1
Gene Symbol: runx1
Brix, A., Belleri, L., Pezzotta, A., Pettinato, E., Mazzola, M., Zoccolillo, M., Marozzi, A., Monteiro, R., Del Bene, F., Mortellaro, A., Pistocchi, A. (2024) ADA2 regulates inflammation and hematopoietic stem cell emergence via the A2bR pathway in zebrafish. Communications biology. 7:615615
Campbell, C.A., Calderon, R., Pavani, G., Cheng, X., Barakat, R., Snella, E., Liu, F., Peng, X., Essner, J.J., Dorman, K.S., McGrail, M., Gadue, P., French, D.L., Espin-Palazon, R. (2024) p65 signaling dynamics drive the developmental progression of hematopoietic stem and progenitor cells through cell cycle regulation. Nature communications. 15:77877787
Han, Y., Sun, K., Yu, S., Qin, Y., Zhang, Z., Luo, J., Hu, H., Dai, L., Cui, M., Jiang, C., Liu, F., Huang, Y., Gao, P., Chen, X., Xin, T., Ren, X., Wu, X., Song, J., Wang, Q., Tang, Z., Chen, J., Zhang, H., Zhang, X., Liu, M., Luo, D. (2024) A Mettl16/m6A/mybl2b/Igf2bp1 axis ensures cell cycle progression of embryonic hematopoietic stem and progenitor cells. The EMBO journal. 43(10):1990-2014
Huang, W., Yue, Y., Hao, W., Zhang, Z., Cai, P., Yang, D. (2024) mTORC1 mediates the expansion of hematopoietic stem and progenitor cells through ribosome biogenesis protein Urb2 in zebrafish. Stem Cell Reports. 19(9):1277-1288
Labudina, A.A., Meier, M., Gimenez, G., Tatarakis, D., Ketharnathan, S., Mackie, B., Schilling, T.F., Antony, J., Horsfield, J.A. (2024) Cohesin composition and dosage independently affect early development in zebrafish. Development (Cambridge, England). 151(15):
Luo, H., Li, Q., Hong, J., Huang, Z., Deng, W., Wei, K., Lu, S., Wang, H., Zhang, W., Liu, W. (2024) Targeting TNF/IL-17/MAPK pathway in hE2A-PBX1 leukemia: effects of OUL35, KJ-Pyr-9, and CID44216842. Haematologica. 109(7):2092-2110
Lv, Y., Li, J., Yu, S., Zhang, Y., Hu, H., Sun, K., Jia, D., Han, Y., Tu, J., Huang, Y., Liu, X., Zhang, X., Gao, P., Chen, X., Shaw Williams, M.T., Tang, Z., Shu, X., Liu, M., Ren, X. (2024) The splicing factor Prpf31 is required for hematopoietic stem and progenitor cell expansion during zebrafish embryogenesis. The Journal of biological chemistry. 300(3):105772
Martínez-López, M.F., de Almeida, C.R., Fontes, M., Mendes, R.V., Kaufmann, S.H.E., Fior, R. (2024) Macrophages directly kill bladder cancer cells through TNF signaling as an early response to BCG therapy. Disease models & mechanisms. 17(8):
Pessoa Rodrigues, C., Collins, J.M., Yang, S., Martinez, C., Kim, J.W., Lama, C., Nam, A.S., Alt, C., Lin, C., Zon, L.I. (2024) Transcripts of repetitive DNA elements signal to block phagocytosis of hematopoietic stem cells. Science (New York, N.Y.). 385:eadn1629eadn1629
Prykhozhij, S.V., Ban, K., Brown, Z.L., Kobar, K., Wajnberg, G., Fuller, C., Chacko, S., Lacroix, J., Crapoulet, N., Midgen, C., Shlien, A., Malkin, D., Berman, J.N. (2024) miR-34a is a tumor suppressor in zebrafish and its expression levels impact metabolism, hematopoiesis and DNA damage. PLoS Genetics. 20:e1011290e1011290
Xu, Y., Guo, R., Huang, T., Guo, C. (2024) miRNA-7145-cuedc2 axis controls hematopoiesis through JAK1/STAT3 signaling pathway. Cell death discovery. 10:209209
Zebrafish Nomenclature Committee (2024) Nomenclature Data Curation (2024). Nomenclature Committee Submission.
Binder, V., Li, W., Faisal, M., Oyman, K., Calkins, D.L., Shaffer, J., Teets, E.M., Sher, S., Magnotte, A., Belardo, A., Deruelle, W., Gregory, T.C., Orwick, S., Hagedorn, E.J., Perlin, J.R., Avagyan, S., Lichtig, A., Barrett, F., Ammerman, M., Yang, S., Zhou, Y., Carson, W.E., Shive, H.R., Blachly, J.S., Lapalombella, R., Zon, L.I., Blaser, B.W. (2023) Microenvironmental control of hematopoietic stem cell fate via CXCL8 and protein kinase C. Cell Reports. 42:112528112528
Cacialli, P., Dogan, S., Linnerz, T., Pasche, C., Bertrand, J.Y. (2023) Minichromosome maintenance protein 10 (mcm10) regulates hematopoietic stem cell emergence in the zebrafish embryo. Stem Cell Reports. 18:153415461534-1546
Cao, P., Cheng, Y., Li, Z., Cheng, Y.J., Chu, X., Geng, C., Yin, X., Li, Y. (2023) Intraocular delivery of ZIF-90-RhB-GW2580 nanoparticles prevents the progression of photoreceptor degeneration. Journal of nanobiotechnology. 21:4444
Darroch, H., Keerthisinghe, P., Sung, Y.J., Rolland, L., Prankerd-Gough, A., Crosier, P.S., Astin, J.W., Hall, C.J. (2023) Infection-experienced HSPCs protect against infections by generating neutrophils with enhanced mitochondrial bactericidal activity. Science advances. 9:eadf9904
Edwards, H.E., Edgington, M.J., Souder, J.P., Gorelick, D.A. (2023) Hemato-vascular specification requires arnt1 and arnt2 genes in zebrafish embryos. Development (Cambridge, England). 150(9)
He, X., Ge, C., Xia, J., Xia, Z., Zhao, L., Huang, S., Wang, R., Pan, J., Cheng, T., Xu, P.F., Wang, F., Min, J. (2023) The Zinc Transporter SLC39A10 Plays an Essential Role in Embryonic Hematopoiesis. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 10(17):e2205345
Heng, J., Shi, B., Zhou, J.Y., Zhang, Y., Ma, D., Yang, Y.G., Liu, F. (2023) Cpeb1b-mediated cytoplasmic polyadenylation of shha mRNA modulates zebrafish definitive hematopoiesis. Proceedings of the National Academy of Sciences of the United States of America. 120:e2212212120e2212212120
Kondo, M., Kimura, K., Kobayashi-Sun, J., Yamamori, S., Taniguchi, M., Traver, D., Kobayashi, I. (2023) The sinusoidal hematopoietic niche is formed by Jam1a via Notch signaling in the zebrafish kidney. iScience. 26:106508106508
Li, H., Luo, Q., Cai, S., Tie, R., Meng, Y., Shan, W., Xu, Y., Zeng, X., Qian, P., Huang, H. (2023) Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells. Stem Cell Research & Therapy. 14:117117
Li, L., Tai, Z., Liu, W., Luo, Y., Wu, Y., Lin, S., Liu, M., Gao, B., Liu, J.X. (2023) Copper overload impairs hematopoietic stem and progenitor cell proliferation via prompting HSF1/SP1 aggregation and the subsequently downregulating FOXM1-Cytoskeleton axis. iScience. 26:106406106406
Liu, W., Lin, S., Li, L., Tai, Z., Liu, J.X. (2023) Zebrafish ELL-associated factors Eaf1/2 modulate erythropoiesis via regulating gata1a expression and WNT signaling to facilitate hypoxia tolerance. Cell regeneration (London, England). 12:1010
Lv, P., Liu, F. (2023) Heme-deficient primitive red blood cells induce HSPC ferroptosis by altering iron homeostasis during zebrafish embryogenesis. Development (Cambridge, England). 150(20):
Mahony, C.B., Copper, L., Vrljicak, P., Noyvert, B., Constantinidou, C., Browne, S., Pan, Y., Palles, C., Ott, S., Higgs, M.R., Monteiro, R. (2023) Lineage skewing and genome instability underlie marrow failure in a zebrafish model of GATA2 deficiency. Cell Reports. 42:112571112571
Mao, A., Li, Z., Ning, G., Zhou, Z., Wei, C., Li, J., He, X., Wang, Q. (2023) Sclerotome-derived PDGF signaling functions as a niche cue responsible for primitive erythropoiesis. Development (Cambridge, England). 150(22):
Sobah, M.L., Scott, A.C., Laird, M., Koole, C., Liongue, C., Ward, A.C. (2023) Socs3b regulates the development and function of innate immune cells in zebrafish. Frontiers in immunology. 14:11197271119727
Tamaoki, J., Maeda, H., Kobayashi, I., Takeuchi, M., Ohashi, K., Gore, A., Bonkhofer, F., Patient, R., Weinstein, B.M., Kobayashi, M. (2023) LSD1 promotes the egress of hematopoietic stem and progenitor cells into the bloodstream during the endothelial-to-hematopoietic transition. Developmental Biology. 501:92-103
Wang, D., Zheng, L., Cheng, B.Y.L., Sin, C.F., Li, R., Tsui, S.P., Yi, X., Ma, A.C.H., He, B.L., Leung, A.Y.H., Sun, X. (2023) Transgenic IDH2R172K and IDH2R140Q zebrafish models recapitulated features of human acute myeloid leukemia. Oncogene. 42(16):1272-1281
Wu, J., Li, J., Chen, K., Liu, G., Zhou, Y., Chen, W., Zhu, X., Ni, T.T., Zhang, B., Jin, D., Li, D., Kang, L., Wu, Y., Zhu, P., Xie, P., Zhong, T.P. (2023) Atf7ip and Setdb1 interaction orchestrates the hematopoietic stem and progenitor cell state with diverse lineage differentiation. Proceedings of the National Academy of Sciences of the United States of America. 120:e2209062120e2209062120
Yang, Z., Guo, D., Zhao, J., Li, J., Zhang, R., Zhang, Y., Xu, C., Ke, T., Wang, Q.K. (2023) Aggf1 Specifies Hemangioblasts at the Top of Regulatory Hierarchy via Npas4l and mTOR-S6K-Emp2-ERK Signaling. Arteriosclerosis, Thrombosis, and Vascular Biology. 43(12):2348-2368
Yu, T., Kuang, H., Wu, X., Huang, Y., Wang, J., Wen, Z. (2023) Cell competition for neuron-derived trophic factor controls the turnover and lifespan of microglia. Science advances. 9:eadf9790
Yue, Y., Tang, Y., Huang, H., Zheng, D., Liu, C., Zhang, H., Liu, Y., Li, Y., Sun, X., Lu, L. (2023) VBP1 negatively regulates CHIP and selectively inhibits the activity of hypoxia-inducible factor (HIF)-1α but not HIF-2α. The Journal of biological chemistry. 299(6):104829
Zhong, D., Jiang, H., Zhou, C., Ahmed, A., Li, H., Wei, X., Lian, Q., Tastemel, M., Xin, H., Ge, M., Zhang, C., Jing, L. (2023) The microbiota regulates hematopoietic stem and progenitor cell development by mediating inflammatory signals in the niche. Cell Reports. 42:112116112116
Begeman, I.J., Emery, B., Kurth, A., Kang, J. (2022) Regeneration and developmental enhancers are differentially compatible with minimal promoters. Developmental Biology. 492:47-58
Biggs, C.M., Cordeiro-Santanach, A., Prykhozhij, S.V., Deveau, A.P., Lin, Y., Del Bel, K.L., Orben, F., Ragotte, R.J., Saferali, A., Mostafavi, S., Dinh, L., Dai, D., Weinacht, K.G., Dobbs, K., Ott de Bruin, L., Sharma, M., Tsai, K., Priatel, J.J., Schreiber, R.A., Rozmus, J., Hosking, M.C., Shopsowitz, K.E., McKinnon, M.L., Vercauteren, S., Seear, M., Notarangelo, L.D., Lynn, F.C., Berman, J.N., Turvey, S.E. (2022) Human JAK1 gain of function causes dysregulated myelopoeisis and severe allergic inflammation. JCI insight. 7(24):
Cacialli, P., Mailhe, M.P., Wagner, I., Merkler, D., Golub, R., Bertrand, J.Y. (2022) Synergistic prostaglandin E synthesis by myeloid and endothelial cells promotes fetal hematopoietic stem cell expansion in vertebrates. The EMBO journal. 41(19):e108536
Dai, Y., Wu, S., Cao, C., Xue, R., Luo, X., Wen, Z., Xu, J. (2022) Csf1rb regulates definitive hematopoiesis in zebrafish. Development (Cambridge, England). 149(16)
Hariom, S.K., Nelson, E.J.R. (2022) Effects of short-term hypergravity on hematopoiesis and vasculogenesis in embryonic zebrafish. Life sciences in space research. 34:21-29
Huang, M., Ahmed, A., Wang, W., Wang, X., Ma, C., Jiang, H., Li, W., Jing, L. (2022) Negative Elongation Factor (NELF) Inhibits Premature Granulocytic Development in Zebrafish. International Journal of Molecular Sciences. 23(7):
Klaus, A., Clapes, T., Yvernogeau, L., Basu, S., Weijts, B., Maas, J., Smal, I., Galjart, N., Robin, C. (2022) CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development. Cell Reports. 39:110957
Li, Y., Tang, C., Liu, F., Zhu, C., Liu, F., Zhu, P., Wang, L. (2022) DNA methylation safeguards the generation of hematopoietic stem and progenitor cells by repression of Notch signaling. Development (Cambridge, England). 149(10):
Liu, Y., Lin, Z., Peng, Y., Jiang, Y., Zhang, X., Zhu, H., Zhang, L., Chen, J., Shu, X., Luo, M., Xie, D., Chen, Y., Liao, H., Liu, M., Zhang, X., Liu, S., Wang, H., Zhou, B., Sun, H. (2022) Embryonic organizer formation disorder leads to multiorgan dysplasia in Down syndrome. Cell Death & Disease. 13:10541054
Potts, K.S., Cameron, R.C., Metidji, A., Ghazale, N., Wallace, L., Leal-Cervantes, A.I., Palumbo, R., Barajas, J.M., Gupta, V., Aluri, S., Pradhan, K., Myers, J.A., McKinstry, M., Bai, X., Choudhary, G.S., Shastri, A., Verma, A., Obeng, E.A., Bowman, T.V. (2022) Splicing factor deficits render hematopoietic stem and progenitor cells sensitive to STAT3 inhibition. Cell Reports. 41:111825111825
Sehring, I.M., Mohammadi, H.F., Haffner-Luntzer, M., Ignatius, A., Huber-Lang, M., Weidinger, G. (2022) Zebrafish fin regeneration involves generic and regeneration-specific osteoblast injury responses. eLIFE. 11:
Sun, R., Sun, L., Xie, X., Li, X., Wu, P., Wang, L., Zhu, P. (2022) Single-cell analysis of transcription factor regulatory networks reveals molecular basis for subtype-specific dysregulation in acute myeloid leukemia. Blood science (Baltimore, Md.). 4:65-75
Wada, Y., Tsukatani, H., Kuroda, C., Miyazaki, Y., Otoshi, M., Kobayashi, I. (2022) Jagged 2b induces intercellular signaling within somites to establish hematopoietic stem cell fate in zebrafish. Development (Cambridge, England). 149(7)
Wang, W., Li, H., Huang, M., Wang, X., Li, W., Qian, X., Jing, L. (2022) Hoxa9/meis1-transgenic zebrafish develops acute myeloid leukaemia-like disease with rapid onset and high penetrance. Open Biology. 12:220172
Weinstein, R., Bishop, K., Broadbridge, E., Yu, K., Carrington, B., Elkahloun, A., Zhen, T., Pei, W., Burgess, S.M., Liu, P., Bresciani, E., Sood, R. (2022) Zrsr2 Is Essential for the Embryonic Development and Splicing of Minor Introns in RNA and Protein Processing Genes in Zebrafish. International Journal of Molecular Sciences. 23(18)
Zhang, X., Yang, Y., Wei, Y., Zhao, Q., Lou, X. (2022) Blf and drl cluster synergistically regulate cell fate commitment during zebrafish primitive hematopoiesis. Development (Cambridge, England). 149(24)
Zhao, S., Feng, S., Tian, Y., Wen, Z. (2022) Hemogenic and aortic endothelium arise from a common hemogenic angioblast precursor and are specified by the Etv2 dosage. Proceedings of the National Academy of Sciences of the United States of America. 119:e2119051119e2119051119
Zhao, S., Zhang, A., Zhu, H., Wen, Z. (2022) The ETS transcription factor Spi2 regulates hematopoietic cell development in zebrafish. Development (Cambridge, England). 149(19)
Avagyan, S., Henninger, J.E., Mannherz, W.P., Mistry, M., Yoon, J., Yang, S., Weber, M.C., Moore, J.L., Zon, L.I. (2021) Resistance to inflammation underlies enhanced fitness in clonal hematopoiesis. Science (New York, N.Y.). 374:768-772
Avagyan, S., Weber, M.C., Ma, S., Prasad, M., Mannherz, W.P., Yang, S., Buenrostro, J.D., Zon, L.I. (2021) Single-cell ATAC-seq reveals GATA2-dependent priming defect in myeloid and a maturation bottleneck in lymphoid lineages. Blood advances. 5:2673-2686
Bresciani, E., Carrington, B., Yu, K., Kim, E.M.K., Zhen, T., Guzman, V.S., Broadbridge, E., Bishop, K., Kirby, M., Harper, U., Wincovitch, S., Dell'Orso, S., Sartorelli, V., Sood, R., Liu, P.P. (2021) Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development. Blood advances. 5(23):4949-4962
Cacialli, P., Mahony, C.B., Petzold, T., Bordignon, P., Rougemont, A.L., Bertrand, J.Y. (2021) A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress. Nature communications. 12:4484
Chen, J., Li, G., Lian, J., Ma, N., Huang, Z., Li, J., Wen, Z., Zhang, W., Zhang, Y. (2021) Slc20a1b is essential for hematopoietic stem/progenitor cell expansion in zebrafish. Science China. Life sciences. 64(12):2186-2201
Gioacchino, E., Koyunlar, C., Zink, J., de Looper, H., de Jong, M., Dobrzycki, T., Mahony, C.B., Hoogenboezem, R., Bosch, D., van Strien, P.M.H., van Royen, M.E., French, P.J., Bindels, E., Gussinklo, K.J., Monteiro, R., Touw, I.P., de Pater, E. (2021) Essential role for Gata2 in modulating lineage output from hematopoietic stem cells in zebrafish. Blood advances. 5:2687-2700
Han, Y., Shao, W., Zhong, D., Ma, C., Wei, X., Ahmed, A., Yu, T., Jing, W., Jing, L. (2021) Zebrafish mafbb Mutants Display Osteoclast Over-Activation and Bone Deformity Resembling Osteolysis in MCTO Patients. Biomolecules. 11(3):
Huang, Z., Chen, K., Chi, Y., Jin, H., Li, L., Zhang, W., Xu, J., Zhang, Y. (2021) Runx1 regulates zebrafish neutrophil maturation via synergistic interaction with c-Myb. The Journal of biological chemistry. 296:100272
Kramer, A., Astuti, Y., Elfstrum, A., Lehrke, M.J., Tolar, J., Blazar, B.R., Blake, A., Taisto, M., Furcich, J.W., Nolan, E.E., Durose, W.W., Webber, B.R., Geisness, A., Wood, D.K., Lund, T. (2021) An irradiated marrow niche reveals a small non-collagenous protein mediator of homing, dermatopontin. Blood advances. 5(18):3609-3622
Mahony, C.B., Cacialli, P., Pasche, C., Monteiro, R., Savvides, S.N., Bertrand, J.Y. (2021) Hapln1b, a central organizer of the extracellular matrix, modulates kit signalling to control developmental haematopoiesis. Blood advances. 5(23):4935-4948
O'Meara, C.P., Guerri, L., Lawir, D.F., Mateos, F., Iconomou, M., Iwanami, N., Soza-Ried, C., Sikora, K., Siamishi, I., Giorgetti, O., Peter, S., Schorpp, M., Boehm, T. (2021) Genetic landscape of T cells identifies synthetic lethality for T-ALL. Communications biology. 4:1201
Peña, O.A., Lubin, A., Hockings, C., Rowell, J., Jung, Y., Hoade, Y., Dace, P.E.I., Valdivia, L.E., Tuschl, K., Boiers, C., Virgilio, M., Richardson, S.E., Payne, E.M. (2021) TLR7 ligation augments hematopoiesis in Rps14 (uS11) deficiency via paradoxical suppression of inflammatory signalling. Blood advances. 5(20):4112-4124
Peña, O.A., Lubin, A., Rowell, J., Hoade, Y., Khokhar, N., Lemmik, H., Mahony, C., Dace, P., Umamahesan, C., Payne, E.M. (2021) Differential Requirement of Gata2a and Gata2b for Primitive and Definitive Myeloid Development in Zebrafish. Frontiers in cell and developmental biology. 9:708113
Póvoa, V., Rebelo de Almeida, C., Maia-Gil, M., Sobral, D., Domingues, M., Martinez-Lopez, M., de Almeida Fuzeta, M., Silva, C., Grosso, A.R., Fior, R. (2021) Innate immune evasion revealed in a colorectal zebrafish xenograft model. Nature communications. 12:1156
Quillien, A., Gilbert, G., Boulet, M., Ethuin, S., Waltzer, L., Vandel, L. (2021) Prmt5 promotes vascular morphogenesis independently of its methyltransferase activity. PLoS Genetics. 17:e1009641
Rajan, V., Collett, K., Woodside, R., Prykhozhij, S.V., Moksa, M., Carles, A., Wong, M., Liebman, M., Hirst, M., Berman, J.N. (2021) Stress hematopoiesis induces a proliferative advantage in TET2 deficiency. Leukemia. 36(3):809-820
Soto, R.A., Najia, M.A.T., Hachimi, M., Frame, J.M., Yette, G.A., Lummertz da Rocha, E., Stankunas, K., Daley, G.Q., North, T.E. (2021) Sequential regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium by Ezh1/2. Stem Cell Reports. 16(7):1718-1734
Weinreb, J.T., Ghazale, N., Pradhan, K., Gupta, V., Potts, K.S., Tricomi, B., Daniels, N.J., Padgett, R.A., De Oliveira, S., Verma, A., Bowman, T.V. (2021) Excessive R-loops trigger an inflammatory cascade leading to increased HSPC production. Developmental Cell. 56(5):627-640.e5
Zhao, Y., Wu, M., Li, J., Meng, P., Chen, J., Huang, Z., Xu, J., Wen, Z., Zhang, W., Zhang, Y. (2021) The spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway. Cell Death & Disease. 12:906
Zizioli, D., Bernardi, S., Varinelli, M., Farina, M., Mignani, L., Bosio, K., Finazzi, D., Monti, E., Polverelli, N., Malagola, M., Borsani, E., Borsani, G., Russo, D. (2021) Development of BCR-ABL1 Transgenic Zebrafish Model Reproducing Chronic Myeloid Leukemia (CML) Like-Disease and Providing a New Insight into CML Mechanisms. Cells. 10(2):
Cai, X., Zhou, Z., Zhu, J., Liao, Q., Zhang, D., Liu, X., Wang, J., Ouyang, G., Xiao, W. (2020) Zebrafish hif-3α modulates erythropoiesis via regulation of gata-1 to facilitate hypoxia tolerance. Development (Cambridge, England). 147(22):
Ding, Y., Wang, W., Ma, D., Liang, G., Kang, Z., Xue, Y., Zhang, Y., Wang, L., Heng, J., Zhang, Y., Liu, F. (2020) Smarca5 mediated epigenetic programming facilitates fetal HSPC development in vertebrates. Blood. 137(2):190-202
Dobrzycki, T., Mahony, C.B., Krecsmarik, M., Koyunlar, C., Rispoli, R., Peulen-Zink, J., Gussinklo, K., Fedlaoui, B., de Pater, E., Patient, R., Monteiro, R. (2020) Deletion of a conserved Gata2 enhancer impairs haemogenic endothelium programming and adult Zebrafish haematopoiesis. Communications biology. 3:71
Doll, L., Aghaallaei, N., Dick, A.M., Welte, K., Skokowa, J., Bajoghli, B. (2020) A zebrafish model for HAX1-associated congenital neutropenia. Haematologica. 106(5):1311-1320
Espanola, S.G., Song, H., Ryu, E., Saxena, A., Kim, E.S., Manegold, J.E., Nasamran, C.A., Sahoo, D., Oh, C.K., Bickers, C., Shin, U., Grainger, S., Park, Y.H., Pandolfo, L., Kang, M.S., Kang, S., Myung, K., Cooper, K.L., Yelon, D., Traver, D., Lee, Y. (2020) Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. Nature cell biology. 22(12):1411-1422
Fang, Y., Lai, K.S., She, P., Sun, J., Tao, W., Zhong, T.P. (2020) Tbx20 Induction Promotes Zebrafish Heart Regeneration by Inducing Cardiomyocyte Dedifferentiation and Endocardial Expansion. Frontiers in cell and developmental biology. 8:738
Ferrero, G., Miserocchi, M., Di Ruggiero, E., Wittamer, V. (2020) A csf1rb mutation uncouples two waves of microglia development in zebrafish. Development (Cambridge, England). 148(1):
Fraint, E., Feliz Norberto, M., Bowman, T.V. (2020) A novel conditioning-free hematopoietic stem cell transplantation model in zebrafish. Blood advances. 4:6189-6198
Frame, J.M., Kubaczka, C., Long, T.L., Esain, V., Soto, R.A., Hachimi, M., Jing, R., Shwartz, A., Goessling, W., Daley, G.Q., North, T.E. (2020) Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production. Developmental Cell. 55(2):133-149.e6
Guo, Y., Cheng, B.Y.L., Wang, D., Ma, A.C.H., He, B.L., Man, T.K., Cheung, M.P.L., Shi, X., Ng, N.K.L., Leung, A.Y.H. (2020) Function of Arl4aa in the Initiation of Hematopoiesis in Zebrafish by Maintaining Golgi Complex Integrity in Hemogenic Endothelium. Stem Cell Reports. 14(4):575-589
He, B.L., Yang, N., Man, C.H., Ng, N.K., Cher, C.Y., Leung, H.C., Kan, L.L., Cheng, B.Y., Lam, S.S., Wang, M.L., Zhang, C.X., Kwok, H., Cheng, G., Sharma, R., Ma, A.C., So, C.E., Kwong, Y.L., Leung, A.Y. (2020) Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia. EMBO Molecular Medicine. 12(4):e10895
Heng, J., Lv, P., Zhang, Y., Cheng, X., Wang, L., Ma, D., Liu, F. (2020) Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling. PLoS Biology. 18:e3000696
Hsu, J., Huang, H.T., Lee, C.T., Choudhuri, A., Wilson, N.K., Abraham, B.J., Moignard, V., Kucinski, I., Yu, S., Hyde, R.K., Tober, J., Cai, X., Li, Y., Guo, Y., Yang, S., Superdock, M., Trompouki, E., Calero-Nieto, F.J., Ghamari, A., Jiang, J., Gao, P., Gao, L., Nguyen, V., Robertson, A.L., Durand, E.M., Kathrein, K.L., Aifantis, I., Gerber, S.A., Tong, W., Tan, K., Cantor, A.B., Zhou, Y., Liu, P.P., Young, R.A., Göttgens, B., Speck, N.A., Zon, L.I. (2020) CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation. Proceedings of the National Academy of Sciences of the United States of America. 117(38):23626-23635
Jiang, Z., Carlantoni, C., Allanki, S., Ebersberger, I., Stainier, D.Y.R. (2020) Tek/Tie2 is not required for cardiovascular development in zebrafish. Development (Cambridge, England). 147(19):
Kang, J.W., Kim, Y., Lee, Y., Myung, K., Kim, Y.H., Oh, C.K. (2020) AML poor prognosis factor, TPD52, is associated with the maintenance of haematopoietic stem cells through regulation of cell proliferation. Journal of cellular biochemistry. 122(3-4):403-412
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Deardorff, M.A., Wilde, J.J., Albrecht, M., Dickinson, E., Tennstedt, S., Braunholz, D., Mönnich, M., Yan, Y., Xu, W., Gil-Rodríguez, M.C., Clark, D., Hakonarson, H., Halbach, S., Michelis, L.D., Rampuria, A., Rossier, E., Spranger, S., Van Maldergem, L., Lynch, S.A., Gillessen-Kaesbach, G., Lüdecke, H.J., Ramsay, R.G., McKay, M.J., Krantz, I.D., Xu, H., Horsfield, J.A., and Kaiser, F.J. (2012) RAD21 Mutations Cause a Human Cohesinopathy. American journal of human genetics. 90(6):1014-1027
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Jin, H., Li, L., Xu, J., Zhen, F., Zhu, L., Liu, P.P., Zhang, M., Zhang, W., and Wen, Z. (2012) Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression. Blood. 119(22):5239-5249
Li, L., Yan, B., Shi, Y.Q., Zhang, W.Q., and Wen, Z.L. (2012) Live imaging reveals differing roles of macrophages and neutrophils during Zebrafish tail fin regeneration. The Journal of biological chemistry. 287(30):25353-25360
Liu, F., Yao, S., Zhang, T., Xiao, C., Shang, Y., Liu, J., and Mo, X. (2012) Kzp Regulates the Transcription of gata2 and pu.1 During Primitive Hematopoiesis in Zebrafish Embryos. Journal of genetics and genomics = Yi chuan xue bao. 39(9):463-471
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van Riel, B., Pakozdi, T., Brouwer, R., Monteiro, R., Tuladhar, K., Franke, V., Bryne, J.C., Jorna, R., Rijkers, E.J., van Ijcken, W., Andrieu-Soler, C., Demmers, J., Patient, R., Soler, E., Lenhard, B., and Grosveld, F. (2012) A Novel Complex, RUNX1-MYEF2, Represses Hematopoietic Genes in Erythroid Cells. Molecular and cellular biology. 32(19):3814-3822
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Zhang, Y., Jin, H., Li, L., Qin, F.X., and Wen, Z. (2011) cMyb regulates hematopoietic stem/progenitor cell mobilization during zebrafish hematopoiesis. Blood. 118(15):4093-101
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Peterkin, T., Gibson, A., and Patient, R. (2009) Common genetic control of haemangioblast and cardiac development in zebrafish. Development (Cambridge, England). 136(9):1465-1474
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Bertrand, J.Y., Kim, A.D., Teng, S., and Traver, D. (2008) CD41+ cmyb+ precursors colonize the zebrafish pronephros by a novel migration route to initiate adult hematopoiesis. Development (Cambridge, England). 135(10):1853-1862
Imamura, S., Uchiyama, J., Koshimizu, E., Hanai, J., Raftopoulou, C., Murphey, R.D., Bayliss, P.E., Imai, Y., Burns, C.E., Masutomi, K., Gagos, S., Zon, L.I., Roberts, T.M., and Kishi, S. (2008) A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis. PLoS One. 3(10):e3364
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Le Guyader, D., Redd, M.J., Colucci-Guyon, E., Murayama, E., Kissa, K., Briolat, V., Mordelet, E., Zapata, A., Shinomiya, H., and Herbomel, P. (2008) Origins and unconventional behavior of neutrophils in developing zebrafish. Blood. 111(1):132-141
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Bussmann, J., Bakkers, J., and Schulte-Merker, S. (2007) Early Endocardial Morphogenesis Requires Scl/Tal1. PLoS Genetics. 3(8):e140
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Additional Citations (21):
ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.
Zebrafish Nomenclature Committee (2021) Nomenclature Data Curation (2021). Nomenclature Committee Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
Zebrafish Nomenclature Committee (2019) Nomenclature Data Curation (2019). Nomenclature Committee Submission.
China Zebrafish Resource Center (CZRC) (2017) CZRC Zebrafish Chromosome 1 All-gene Knockout Project (ZKO project) mutant data submission. ZFIN Direct Data Submission.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.
ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Scientific Curation. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
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