ZFIN Image: Griffin et al., 2021, Fig. 1

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Figure Caption

Fig. 1 The Epilepsy Zebrafish Project (EZP).

a Overview of the zebrafish epilepsy disease model discovery workflow from human genome-wide association studies (GWAS) to the generation of zebrafish models and phenotypic characterization. b Heatmap of homology scoring for all EZP zebrafish lines generated. Red circles indicate genes for which mutant zebrafish lines were previously published. c Tissue expression profiles of EZP zebrafish target genes. Heatmap represents the maximum number of sequence reads for each gene per tissue. d Developmental gene expression profiles for EZP lines. e Representative frame-shift mutant lines confirmed for depdc5 and eef1a2.

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Acknowledgments

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