Gene

dnm1b

ID
ZDB-GENE-100920-3
Name
dynamin 1b
Symbol
dnm1b Nomenclature History
Previous Names
  • si:ch73-310g9.3
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable GTPase activity and microtubule binding activity. Predicted to be involved in receptor internalization and synaptic vesicle endocytosis. Predicted to act upstream of or within endocytosis. Predicted to be located in cytoskeleton. Predicted to be active in several cellular components, including microtubule; plasma membrane; and synapse. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 31. Orthologous to human DNM1 (dynamin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dnm1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
developmental and epileptic encephalopathy 31 Alliance Developmental and epileptic encephalopathy 31 616346
Associated With dnm1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019762 Dynamin, GTPase region, conserved site
Domain IPR000375 Dynamin stalk domain
Domain IPR001401 Dynamin, GTPase domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR003130 Dynamin GTPase effector
Domain IPR020850 GTPase effector domain
Domain IPR030381 Dynamin-type guanine nucleotide-binding (G) domain
Family IPR022812 Dynamin superfamily
Family IPR027741 Dynamin-1
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length Dynamin-1 Dynamin, GTPase domain Dynamin GTPase effector Dynamin, GTPase region, conserved site Dynamin stalk domain Dynamin superfamily Dynamin-type guanine nucleotide-binding (G) domain GTPase effector domain PH-like domain superfamily Pleckstrin homology domain P-loop containing nucleoside triphosphate hydrolase
UniProtKB:E7FC95 858
UniProtKB:E9QF63 846
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations