ZFIN is now using GRCz12tu for Genomic Data
Gene
plcb1l
- ID
- ZDB-GENE-121210-1
- Name
- phospholipase C beta 1-like
- Symbol
- plcb1l Nomenclature History
- Previous Names
-
- plcb1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium ion binding activity and phosphatidylinositol-4,5-bisphosphate phospholipase C activity. Predicted to act upstream of or within intracellular signal transduction and lipid catabolic process. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 12 and myelodysplastic syndrome. Orthologous to human PLCB1 (phospholipase C beta 1).
- Genome Resources
-
- Alliance (1)
- Gene:100149080 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Griffin et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 12 | Alliance | Developmental and epileptic encephalopathy 12 | 613722 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0AB32TCL4 | InterPro | 912 |
| UniProtKB:A0AC58I6U1 | InterPro | 1076 |
| UniProtKB:A0AC58I6U3 | InterPro | 1174 |
| UniProtKB:A0AC58I6V1 | InterPro | 1101 |
| UniProtKB:A0AC58I6X6 | InterPro | 1199 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance