Gene
prickle1a
- ID
- ZDB-GENE-030724-5
- Name
- prickle homolog 1a
- Symbol
- prickle1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have zinc ion binding activity. Involved in several processes, including determination of left/right symmetry; gastrulation; and nervous system development. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 1B. Is expressed in several structures, including central nervous system; ectoderm; eye; mesoderm; and pharyngeal arch. Orthologous to human PRICKLE1 (prickle planar cell polarity protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu2428 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 29 figures from 11 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| progressive myoclonus epilepsy 1B | Alliance | Epilepsy, progressive myoclonic 1B | 612437 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | LIM1 prickle | LIM2 prickle | LIM3 prickle | PET domain | PET prickle | Prickle/Espinas/Testin | Zinc finger, LIM-type |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6WGK5
|
793 | |||||||
|
UniProtKB:F1Q6J9
|
793 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prickle1a-201
(1)
|
Ensembl | 5,108 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-prickle1a | polyclonal | IgG | Rabbit |
|
AnaSpec
|
2 |
Plasmids