Gene

prickle1a

ID
ZDB-GENE-030724-5
Name
prickle homolog 1a
Symbol
prickle1a Nomenclature History
Previous Names
  • pk1 (2)
  • pk1a (1)
  • prickle1
  • fk71b09
  • wu:fk71b09 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have zinc ion binding activity. Involved in several processes, including determination of left/right symmetry; gastrulation; and nervous system development. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 1B. Is expressed in several structures, including central nervous system; ectoderm; eye; mesoderm; and pharyngeal arch. Orthologous to human PRICKLE1 (prickle planar cell polarity protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
29 figures from 11 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prickle1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
progressive myoclonus epilepsy 1B Alliance Epilepsy, progressive myoclonic 1B 612437
Associated With prickle1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001781 Zinc finger, LIM-type
Domain IPR010442 PET domain
Domain IPR033723 PET prickle
Domain IPR033725 LIM1 prickle
Domain IPR033726 LIM2 prickle
Domain IPR033727 LIM3 prickle
Domain Details Per Protein
Protein Length LIM1 prickle LIM2 prickle LIM3 prickle PET domain PET prickle Zinc finger, LIM-type
UniProtKB:Q7ZZC5 793
UniProtKB:F1Q6J9 793
UniProtKB:B3DGT8 793
UniProtKB:Q6WGK5 793
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-prickle1a polyclonal IgG Rabbit
  • WB
AnaSpec
2
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations