header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-3158
Gene Name: solute carrier family 2 member 1a
Gene Symbol: slc2a1a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: fc29a02, glut1 (1), glut1a (1), slc2a1 (1), glut1b (1), wu:fc29a02, zglut1b (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Exhibits glucose transmembrane transporter activity. Involved in several processes, including endothelial cell development; glucose import; and vasculature development. Predicted to localize to the plasma membrane. Human ortholog(s) of this gene implicated in brain disease (multiple); carbohydrate metabolic disorder; myelomeningocele; obesity; and type 2 diabetes mellitus. Is expressed in several structures, including cranial vasculature; liver; nervous system; otic vesicle; and pleuroperitoneal region. Orthologous to human SLC2A1 (solute carrier family 2 member 1).
Genome Resources: Alliance (1),  Gene:555778 (1),  Ensembl(GRCz11):ENSDARG00000001437 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fcc27Gt Transgenic Insertion Unknown Splicing Variant DNA
la028504Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43972 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43973 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-slc2a1a N/A 4
    MO2-slc2a1a N/A 1
    MO3-slc2a1a N/A 1
    MO4-slc2a1a N/A 1
    DISEASE ASSOCIATED WITH slc2a1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    childhood onset GLUT1 deficiency syndrome 2 Alliance GLUT1 deficiency syndrome 2, childhood onset 612126
    dystonia 9 Alliance Dystonia 9 601042
    idiopathic generalized epilepsy 12 Alliance {Epilepsy, idiopathic generalized, susceptibility to, 12} 614847
    GLUT1 deficiency syndrome 1, infantile onset, severe 606777
    Stomatin-deficient cryohydrocytosis with neurologic defects 608885
    DISEASE ASSOCIATED WITH slc2a1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glucose import (more)
    Cellular Component plasma membrane (more)
    Molecular Function glucose transmembrane transporter activity (more)
    GO Terms (all 12)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA slc2a1a-201 (1)    Ensembl 1792
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-slc2a1 polyclonal Rabbit IHC Dako North America, Inc.
    3
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc2a1a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(slc2a1a:mCherry) slc2a1a mCherry Danio rerio 1 1
    MARKER RELATIONSHIPS
    slc2a1a Contained in: [BAC] CH211-35J18 (order this)
    slc2a1a Contains: [SNP] rs3729253 (1)
    slc2a1a Encodes: [EST] fc29a02
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001039808 (1) 1696 bp
    Genomic GenBank:AL772391 (1) 146397 bp
    Select Tool
    Polypeptide UniProtKB:Q285P3 (1) 488 aa
    Sequence Clusters UniGene:132485 (1)
    Sequence Information (all 11)
    ORTHOLOGY for slc2a1a ( Chr: 23 )
    CITATIONS (51)