Gene
slc6a1b
- ID
- ZDB-GENE-041114-57
- Name
- solute carrier family 6 member 1b
- Symbol
- slc6a1b Nomenclature History
- Previous Names
-
- gat-1 (1)
- slc6a1
- wu:fj45h10
- wu:fq41d04
- zgc:103663
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable gamma-aminobutyric acid:sodium:chloride symporter activity. Predicted to be involved in amino acid transport and sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in axon; cell surface; and plasma membrane. Is expressed in basal plate midbrain region and nervous system. Human ortholog(s) of this gene implicated in alcohol dependence and myoclonic-atonic epilepsy. Orthologous to human SLC6A1 (solute carrier family 6 member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103663 (21 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| myoclonic-atonic epilepsy | Alliance | Myoclonic-atonic epilepsy | 616421 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Sodium:neurotransmitter symporter | Sodium:neurotransmitter symporter, GABA, GAT-1 | Sodium:neurotransmitter symporter superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q5U3E5 | InterPro | 600 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc6a1b-201
(1)
|
Ensembl | 3,993 nt | ||
| ncRNA |
slc6a1b-002
(1)
|
Ensembl | 645 nt |
Interactions and Pathways
No data available
Plasmids
No data available