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Gene

slc2a1b

ID
ZDB-GENE-090915-1
Name
solute carrier family 2 member 1b
Symbol
slc2a1b Nomenclature History
Previous Names
  • si:dkey-92f12.1
  • zglut1a (2)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Enables D-glucose transmembrane transporter activity. Acts upstream of or within sprouting angiogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including heart; intestine; kidney; liver; and yolk. Human ortholog(s) of this gene implicated in brain disease (multiple); carbohydrate metabolic disorder; myelomeningocele; obesity; and type 2 diabetes mellitus. Orthologous to human SLC2A1 (solute carrier family 2 member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc2a1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
childhood onset GLUT1 deficiency syndrome 2 Alliance GLUT1 deficiency syndrome 2, childhood onset 612126
dystonia 9 Alliance Dystonia 9 601042
idiopathic generalized epilepsy 12 Alliance {Epilepsy, idiopathic generalized, susceptibility to, 12} 614847
GLUT1 deficiency syndrome 1, infantile onset, severe 606777
Stomatin-deficient cryohydrocytosis with neurologic defects 608885
Associated With slc2a1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR005829 Sugar transporter, conserved site
Domain IPR020846 Major facilitator superfamily domain
Family IPR003663 Sugar/inositol transporter
Family IPR005828 Major facilitator, sugar transporter-like
Homologous_superfamily IPR036259 MFS transporter superfamily
Domain Details Per Protein
Protein Length Major facilitator, sugar transporter-like Major facilitator superfamily domain MFS transporter superfamily Sugar/inositol transporter Sugar transporter, conserved site
UniProtKB:A0A2R8QGQ5 456
UniProtKB:A0A2R8Q853 463
UniProtKB:F1R0Q1 489
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations