Publication	Data		Fish	Anatomy
Navajas Acedo et al., 2019	Fig. 1		gpc4fr6/fr6	dorsal-ventral polarized posterior lateral line neuromast neuromast hair cell whorled, abnormal dorsal-ventral polarized posterior lateral line neuromast positional polarity, abnormal
	Fig. s1		gpc4fr6/fr6	dorsal-ventral polarized posterior lateral line neuromast establishment of cell polarity disrupted, abnormal dorsal-ventral polarized posterior lateral line neuromast positional polarity, abnormal
	Fig. s2		gpc4fr6/fr6	anterior-posterior polarized posterior lateral line neuromast neuromast hair cell disoriented, abnormal anterior-posterior polarized posterior lateral line neuromast positional polarity, abnormal dorsal-ventral polarized posterior lateral line neuromast neuromast hair cell disoriented, abnormal dorsal-ventral polarized posterior lateral line neuromast positional polarity, abnormal
	Fig. s5		gpc4fr6/fr6	dorsal lateral line neuromast positional polarity, abnormal dorsal-ventral polarized posterior lateral line neuromast neuromast support cell position, abnormal
Hu et al., 2018	Fig. 1		gpc4fr6/fr6; ha01Tg	endoderm cell migration involved in gastrulation decreased efficacy, abnormal endoderm cell migration involved in gastrulation process quality, abnormal endoderm convergent extension involved in gastrulation decreased efficacy, abnormal endoderm convergent extension involved in gastrulation process quality, abnormal
	Fig. 5		gpc4fr6/fr6; ha01Tg	anatomical line ab2-fn labeling increased amount, abnormal whole organism ab2-fn labeling increased amount, abnormal
	Fig. 6		gpc4fr6/fr6; ha01Tg	endoderm increased width, abnormal
	Fig. 8		gpc4fr6/fr6	whole organism mmp14a expression decreased amount, abnormal whole organism mmp14b expression decreased amount, abnormal
	Fig. S5		gpc4fr6/fr6; ha01Tg	anatomical line ab1-lam labeling increased amount, abnormal
	Fig. S8		gpc4fr6/fr6; ha01Tg	endoderm increased width, abnormal
Williams et al., 2018	Fig. 1		gpc4m818/m818	axis elongation decreased process quality, abnormal post-vent region decreased length, abnormal trunk decreased length, abnormal
Ling et al., 2017	Fig. 2		gpc4hi1688Tg/hi1688Tg	Meckel's cartilage shortened, abnormal
	Fig. 3		gpc4hi1688Tg/hi1688Tg; ir937Tg	chondrocyte microtubule organizing center disorganized, abnormal Meckel's cartilage cartilage morphogenesis process quality, abnormal Meckel's cartilage chondrocyte morphology, abnormal Meckel's cartilage chondrocyte positional polarity, abnormal
	Fig. 4		gpc4hi1688Tg/hi1688Tg; ir937Tg	ceratobranchial 5 bone absent, abnormal endochondral bone absent, abnormal endochondral ossification disrupted, abnormal maxilla absent, abnormal ossification process quality, abnormal quadrate absent, abnormal retroarticular absent, abnormal
	Fig. 5		gpc4hi1688Tg/hi1688Tg ,   gpc4hi1688Tg/hi1688Tg; ir937Tg	head muscle decreased length, abnormal interhyal cartilage chondrocyte decreased amount, abnormal intermandibularis disorganized, abnormal quadrate-anguloarticular joint morphology, abnormal retroarticular malformed, abnormal retroarticular shortened, abnormal
Santos-Ledo et al., 2017	Fig. 4		gpc4fr6/fr6	mandibular arch skeleton chondrocyte morphology, abnormal mandibular arch skeleton chondrocyte position, abnormal
Rochard et al., 2016	Fig. 1		gpc4hi1688Tg/hi1688Tg	palate decreased length, abnormal palate increased width, abnormal
	Fig. 2		gpc4hi1688Tg/hi1688Tg	palate chondrocyte irregular spatial pattern, abnormal
Venero Galanternik M. et al., 2016	Fig. 1		gpc4fr6/fr6; zf106Tg	posterior lateral line neuromast primordium migration process quality, abnormal posterior lateral line primordium mislocalised anteriorly, abnormal posterior lateral line primordium mislocalised dorsally, abnormal posterior lateral line primordium mislocalised, abnormal
	Fig. 2		gpc4fr6/fr6	posterior lateral line primordium etv4 expression decreased amount, abnormal
	Fig. 5		gpc4fr6/fr6	horizontal myoseptum cxcr4b expression decreased amount, abnormal muscle pioneer ab1-eng labeling decreased amount, abnormal
	Fig. 6		gpc4fr6/fr6	horizontal myoseptum en1a expression decreased amount, abnormal horizontal myoseptum en2a expression decreased amount, abnormal horizontal myoseptum ptch2 expression decreased amount, abnormal somite id1 expression increased amount, abnormal
	Fig. S1		gpc4fr6/fr6; zf106Tg	posterior lateral line primordium circular, abnormal posterior lateral line primordium increased thickness, abnormal posterior lateral line primordium morphology, abnormal
Sisson et al., 2015	Fig. 2		gpc4fr6/fr6	ceratohyal cartilage chondrocyte circular, abnormal ceratohyal cartilage condensed, abnormal ceratohyal cartilage deformed, abnormal ceratohyal cartilage perpendicular to whole organism anterior-posterior axis, abnormal Meckel's cartilage chondrocyte circular, abnormal Meckel's cartilage condensed, abnormal Meckel's cartilage deformed, abnormal Meckel's cartilage perpendicular to whole organism anterior-posterior axis, abnormal Meckel's cartilage shape, abnormal pharyngeal arch cartilage deformed, abnormal
	Fig. 3		gpc4fr6/fr6; y1Tg ,   gpc4fr6/fr6	convergent extension process quality, abnormal whole organism anterior-posterior axis decreased length, abnormal
	Fig. 4		gpc4m818/m818 ,   gpc4fr6/fr6	symplectic decreased length, abnormal
	Fig. 5		gpc4fr6/fr6	ceratohyal cartilage chondrocyte decreased size, abnormal ceratohyal cartilage decreased length, abnormal ceratohyal cartilage decreased volume, abnormal symplectic decreased length, abnormal symplectic decreased volume, abnormal
Young et al., 2014	Fig. 2		WT + MO1-gpc4	whole organism morphology, abnormal
Castanon et al., 2013	Fig. S7		WT + MO1-gpc4	anterior neural plate increased width, abnormal convergent extension disrupted, abnormal notochord decreased length, abnormal notochord increased width, abnormal prechordal plate elongated, abnormal whole organism decreased length, abnormal
Dohn et al., 2013	Fig. 3		gpc4m119/m119	convergent extension process quality, abnormal
	Fig. 4		gpc4m119/m119	cell extracellular matrix increased size, abnormal cell extracellular matrix organization quality, abnormal
Flowers et al., 2012	Fig. 3		gpc4fr6/fr6	notochord cell disorganized, abnormal
de Andrea et al., 2011	Fig. 3		gpc4m119/m119	cranial cartilage extracellular matrix composition, abnormal
Wiweger et al., 2011	Fig. 1		gpc4m119/m119	glycosaminoglycan metabolic process disrupted, abnormal
	Fig. 3		gpc4m119/m119	ceratohyal cartilage chondrocyte disorganized, abnormal ceratohyal cartilage structure, abnormal Meckel's cartilage chondrocyte disorganized, abnormal Meckel's cartilage structure, abnormal
	Fig. Table 2		gpc4m119/m119	cranial cartilage deformed, abnormal whole organism anterior-posterior axis dwarf-like, abnormal
Yang et al., 2011	Fig. 3		gpc4fr6/fr6	post-anal tail morphogenesis disrupted, abnormal post-anal tail morphogenesis having extra processual parts post-anal tail morphogenesis, abnormal post-vent region deformed, abnormal whole organism has extra parts of type post-vent region, abnormal
	Fig. 4		gpc4fr6/fr6	notochord morphogenesis disrupted, abnormal post-anal tail morphogenesis having extra processual parts post-anal tail morphogenesis, abnormal whole organism has extra parts of type post-vent region, abnormal
	Fig. 5		gpc4fr6/fr6	notochord morphogenesis disrupted, abnormal notochord posterior region cell separated from notochord posterior region cell, abnormal
	Fig. 6		gpc4fr6/+; c161Tg	notochord formation disrupted, abnormal post-anal tail morphogenesis disrupted, abnormal post-anal tail morphogenesis having extra processual parts post-anal tail morphogenesis, abnormal
	Fig. 7		gpc4fr6/+; c161Tg	mesodermal cell migration delayed, abnormal notochord morphogenesis disrupted, abnormal post-anal tail morphogenesis disrupted, abnormal whole organism has extra parts of type post-vent region, abnormal
Borovina et al., 2010	Fig. 5		gpc4m119/m119; hsc5Tg ,   gpc4m119/m119 ,   gpc4m119/m119	convergent extension involved in axis elongation disrupted, abnormal floor plate ciliated cell oriented towards floor plate anterior region, abnormal Kupffer's vesicle ciliated cell oriented towards Kupffer's vesicle anterior region, abnormal pronephric duct ciliated cell oriented towards pronephric duct anterior region, abnormal somite increased width, abnormal whole organism medial-lateral axis increased length, abnormal
LeClair et al., 2009	Fig. 1		gpc4m818/m818	ceratohyal cartilage decreased length, abnormal ceratohyal cartilage increased thickness, abnormal ethmoid cartilage decreased length, abnormal hypophyseal fenestra increased size, abnormal neurocranial trabecula increased distance neurocranial trabecula, abnormal palatoquadrate cartilage decreased length, abnormal palatoquadrate cartilage increased thickness, abnormal symplectic decreased length, abnormal symplectic increased thickness, abnormal
Shao et al., 2009	Fig. 7		WT + MO2-gpc4	axis shortened, abnormal convergent extension involved in axis elongation process quality, abnormal convergent extension process quality, abnormal
Sisson et al., 2009	Fig. 5		gpc4m818/m818	convergent extension involved in axis elongation disrupted, abnormal whole organism decreased length, abnormal
	Fig. S1		gpc4m818/m818	convergent extension involved in axis elongation disrupted, abnormal whole organism decreased length, abnormal
Coyle et al., 2008	Fig. 5		gpc4m119/m119	axis decreased length, abnormal axis increased width, abnormal convergent extension involved in gastrulation disrupted, abnormal extension decreased length, abnormal forebrain increased width, abnormal post-vent region decreased length, abnormal rhombomere increased width, abnormal somite increased width, abnormal whole organism decreased length, abnormal whole organism morphology, abnormal
Caneparo et al., 2007	Fig. 5		gpc4m119/m119	cell migration involved in gastrulation delayed, abnormal
Yin et al., 2007	Fig. 1		gpc4m119/m119	myotome decreased length, abnormal somite decreased length, abnormal somite increased width, abnormal
Yin et al., 2007	Fig. 1		gpc4m119/m119	muscle cell migration disrupted, abnormal slow muscle cell decreased length, abnormal slow muscle cell disorganized, abnormal striated muscle cell development disrupted, abnormal
	Fig. 2		gpc4m119/m119	adaxial cell shape, abnormal cell morphogenesis disrupted, abnormal
Phenotype Annotation (1994-2006)	Fig. for (hi1688)		gpc4hi1688Tg	pharyngeal arch 3-7 skeleton quality, abnormal post-vent region quality, abnormal somite quality, abnormal whole organism shape, abnormal
	Fig. for (hi1934)		gpc4hi1934Tg	notochord undulate, abnormal pharyngeal arch 3-7 skeleton quality, abnormal somite quality, abnormal whole organism decreased length, abnormal
	Fig. for (m119)		gpc4m119/m119 (AB)	notochord quality, abnormal whole organism shape, abnormal
Amsterdam et al., 2004	text only		gpc4hi1688Tg/hi1688Tg	head decreased size, abnormal notochord undulate, abnormal somite U-shaped, abnormal trunk decreased length, abnormal
Marlow et al., 2004	Fig. 2		gpc4m119/m119	extension decreased length, abnormal post-vent region decreased length, abnormal
	Fig. 3		gpc4m119/m119	extension aplastic, abnormal post-vent region decreased length, abnormal whole organism decreased length, abnormal
Golling et al., 2002	Fig. 1		gpc4hi1688Tg/hi1688Tg	post-vent region decreased length, abnormal somite U-shaped, abnormal
Biemar et al., 2001	Fig. 6		gpc4m818/m818	pancreas development decreased process quality, abnormal pancreatic bud split medially, abnormal
Topczewski et al., 2001	Fig. 6		gpc4m119/m119 (AB)	eye mislocalised medially, abnormal eye morphology, abnormal
Alexander et al., 1999	Fig. 7		gpc4m119/m119	convergent extension involved in gastrulation disrupted, abnormal endoderm mislocalised, abnormal endothelial cell mislocalised, abnormal
Solnica-Krezel et al., 1996	Fig. 1		gpc4m119/m119 (AB)	notochord posterior region folded, abnormal post-vent region malformed, abnormal post-vent region truncated, abnormal whole organism anterior-posterior axis decreased length, abnormal
	Fig. 3		gpc4m119/m119 (AB)	axis decreased length, abnormal convergent extension involved in axis elongation disrupted, abnormal
	Fig. 4		gpc4m119/m119 (AB)	axis decreased length, abnormal convergent extension involved in axis elongation disrupted, abnormal neural keel decreased length, abnormal somite increased width, abnormal
	Fig. 9		gpc4m119/m119 (AB)	post-vent region malformed, abnormal post-vent region truncated, abnormal ventral fin fold cell dislocated proctodeum, abnormal
Stemple et al., 1996	Fig. 8		gpc4m119/m119 (AB)	post-vent region notochord folded, abnormal
	Fig. T1		gpc4m119/m119 (AB)	dorsal convergence delayed, abnormal