Gene
gpc4
- ID
- ZDB-GENE-011119-1
- Name
- glypican 4
- Symbol
- gpc4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Acts upstream of with a positive effect on lamellipodium organization; regulation of cell migration; and regulation of extracellular matrix assembly. Acts upstream of or within several processes, including gastrulation; post-anal tail morphogenesis; and skeletal system development. Predicted to be located in plasma membrane and side of membrane. Predicted to be active in cell surface and synapse. Is expressed in several structures, including axial chorda mesoderm; blastomere; lateral line system; quadrate-anguloarticular joint; and tail bud. Human ortholog(s) of this gene implicated in Keipert syndrome. Orthologous to human GPC4 (glypican 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 67 figures from 32 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Keipert syndrome | Alliance | Keipert syndrome | 301026 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR001863 | Glypican |
Domain Details Per Protein
| Protein | Additional Resources | Length | Glypican |
|---|---|---|---|
| UniProtKB:B3DJ94 | InterPro | 557 |
Interactions and Pathways
No data available
Plasmids
No data available