Gene
gpc4
- ID
- ZDB-GENE-011119-1
- Name
- glypican 4
- Symbol
- gpc4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Involved in several processes, including gastrulation; post-anal tail morphogenesis; and skeletal system development. Predicted to localize to cell surface; extracellular region; and synapse. Is expressed in several structures, including axial chorda mesoderm; blastomere; lateral line system; quadrate-anguloarticular joint; and tail bud. Human ortholog(s) of this gene implicated in Keipert syndrome. Orthologous to human GPC4 (glypican 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 67 figures from 32 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Keipert syndrome | Alliance | Keipert syndrome | 301026 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR001863 | Glypican |
Domain Details Per Protein
| Protein | Length | Glypican |
|---|---|---|
|
UniProtKB:F1QKN6
|
557 | |
|
UniProtKB:B3DJ94
|
557 | |
|
UniProtKB:Q90Z52
|
557 |
Interactions and Pathways
No data available
Plasmids
No data available