FIGURE

Fig. 2

ID

ZDB-FIG-080512-4

Publication

Marlow et al., 2004 - No tail co-operates with non-canonical Wnt signaling to regulate posterior body morphogenesis in zebrafish

Other Figures

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Fig. 2

The ntl gene interacts with kny and ppt, but not slb. At 26 hpf, the tail extends beyond the yolk extension (ye) in wild-type embryos (A). Embryos with the slb mutation (B) have normal tails, whereas ppt (C), kny (D) and ntl (E) embryos have shorter tails (^*). Embryos with the slb;ntl double mutation (F) have cyclopic eyes (ey) and tail defects like individual mutants, and slb;ppt (G) double mutants are shorter than individual mutants. The tail does not extend beyond the yolk tube in ppt;ntl (H) and kny;ntl (I) double-mutant embryos. At the ten-somite stage, slb/wnt11 is expressed in the notochord of wild-type (J) embryos but is absent in ntl mutants (K). Posterior ppt/wnt5 expression is mediolaterally broader in wild-type (L) but persists in ntl (M) embryos, and kny expression is comparable between the wild type (N) and ntl mutants (O). (A-I) Lateral views. (J-O) Dorsal posterior views. Scale bar=50 μm (A-I) and 100 μm (J-O).

Expression Data

Genes:	gpc4 wnt5b wnt11f2
Fish:	WT tbxta^b195/b195
Anatomical Terms:	notochord tail bud
Stage:	10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gpc4^m119/m119 tbxta^b195/b195 wnt5b^ta98/ta98 wnt11f2^tz216/tz216 gpc4^m119/m119; tbxta^b195/b195 wnt5b^ta98/ta98; tbxta^b195/b195 wnt11f2^tz216/tz216; tbxta^b195/b195 wnt11f2^tz216/tz216; wnt5b^ta98/ta98
Observed In:	extension eye post-vent region whole organism
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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