FIGURE

Fig. 7

ID

ZDB-FIG-110622-91

Publication

Yang et al., 2011 - BMP and non-canonical Wnt signaling are required for inhibition of secondary tail formation in zebrafish

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Fig. 7

BMP regulates posterior mesoderm cells of the tailbud to inhibit secondary tail formation. (A-J) All panels show the midline section of tails of Tg(flh:EGFP)-expressing zebrafish embryos (green) at the indicated time points after anti-Tbx6 (red) immunostaining. Tbx6-positive mesoderm cells in mfn embryos (B) shows detention in the posterior tailbud, when compared with wild-type embryos (A) at the same stage. A more wild-type-like movement of posterior mesoderm cells in kny embryos is shown in F and H. Note that eventually ectopic Tbx6-positive mesoderm cells are shown in the secondary tail domain of mfn (D) and kny (J) embryos. Arrowheads mark the ventroposterior mesoderm cells in the taillbud. All tails are flat mounted laterally.

Expression Data

Genes:	EGFP tbx16l
Fish:	c161Tg gpc4^fr6/+; c161Tg tll1^tc263a/+; c161Tg
Anatomical Terms:	mesoderm tail bud
Stage Range:	14-19 somites to 26+ somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gpc4^fr6/+; c161Tg tll1^tc263a/+; c161Tg
Observed In:	mesodermal cell migration notochord morphogenesis post-anal tail morphogenesis post-vent region whole organism
Stage Range:	14-19 somites to 26+ somites

Phenotype Detail

Acknowledgments

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