FIGURE

Fig. 3

ID

ZDB-FIG-131213-59

Publication

Dohn et al., 2013 - Planar cell polarity proteins differentially regulate extracellular matrix organization and assembly during zebrafish gastrulation

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Fig. 3

glypican4 and frizzled7 mutant embryos have increased fibronectin assembly. (A?C) Top panels show morphological convergence and extension phenotypes at tailbud stage (see arrowheads) of wild type, glypican4 mutant, and MZfrizzled7a/7b mutant embryos. Middle two panels show confocal images of fibronectin (Fn) immunolabeling without and with nuclear DAPI staining. Scale bars=20 μm. The bottom images in (A) and (B) show Fn expression in cross-sections (x.s.) of tailbud stage embryos (n, notochord).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gpc4^m119/m119 fzd7a^e3/e3; fzd7b^{hu3495/hu3495}
Observed In:	convergent extension
Stage:	Bud

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 383(1), Dohn, M.R., Mundell, N.A., Sawyer, L.M., Dunlap, J.A., and Jessen, J.R., Planar cell polarity proteins differentially regulate extracellular matrix organization and assembly during zebrafish gastrulation, 39-51, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.