FIGURE

Figure 8

ID

ZDB-FIG-200406-233

Publication

García-González et al., 2020 - Identification of slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour

Other Figures

All Figure Page

Back to All Figure Page

Figure 8

Gene expression data for <italic>slit3</italic> mutant and wild type zebrafish.
Quantitative real-time PCR analysis of five-day-old wild type <italic>slit3<sup>sa1569+/+</sup></italic>, <italic>slit3<sup>sa1569/+</sup></italic> heterozygous and <italic>slit3<sup>sa1569/sa1569</sup></italic> homozygous mutant larvae. Quantitative PCR analysis of gene expression was performed for members of (A) dopaminergic signalling pathway, (B) adrenoreceptors, (C) serotonin signalling pathway and (D) nicotinic cholinergic receptors. (Total n=30, 3 samples per experimental group with n=10 embryos per sample). Only htr1aa ([F(2,6)=44], p=0.0003) showed a significant difference across genotypes after correcting for multiple testing. *Two-way ANOVA followed by post-hoc Tukey test (p < 0.05). Figure 8—source data 1.

Expression Data

Genes:	adra1aa adra1d adra2b adra2c adra2da adra2db chrna2a chrna3 chrna4b chrna5 chrna6 chrna7a chrnb2 chrnb3b chrnb4 drd1b drd2a drd3 htr1aa htr1ab htr1b htr2aa htr2cl1 htr2cl2 htr4 htr5aa htr6 htr7a slc6a3 slc6a4a
Fish:	WT slit3^{sa1569/sa1569} slit3^sa202/+ slit3^sa1569/+
Anatomical Term:	whole organism
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	slit3^{sa1569/sa1569} slit3^sa1569/+
Observed In:	whole organism
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife