Gene

slc6a4a

ID
ZDB-GENE-060314-1
Name
solute carrier family 6 member 4a
Symbol
slc6a4a Nomenclature History
Previous Names
  • serta (1)
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Exhibits serotonin:sodium symporter activity. Involved in serotonin transport. Predicted to localize to integral component of plasma membrane and neuron projection. Is expressed in brain; pharynx; and spinal cord. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; alexithymia; anxiety disorder (multiple); heart disease (multiple); and mental depression (multiple). Orthologous to human SLC6A4 (solute carrier family 6 member 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc6a4a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
anxiety disorder Alliance {Anxiety-related personality traits} 607834
{Obsessive-compulsive disorder} 164230
Associated With slc6a4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000175 Sodium:neurotransmitter symporter
Homologous_superfamily IPR037272 Sodium:neurotransmitter symporter superfamily
Domain Details Per Protein
Protein Length Sodium:neurotransmitter symporter Sodium:neurotransmitter symporter superfamily
UniProtKB:Q1WGB5 646
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations