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General Information
ZIRC
ZFIN ID: ZDB-GENE-090505-3
Gene Name: cholinergic receptor, nicotinic, alpha 4b
Gene Symbol: chrna4b
Sequence Ontology ID : SO:0001217

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Previous Name: chrna4

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(Including Attributions)
Location: Chr: 11 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Contributes to acetylcholine receptor activity. Involved in response to nicotine. Localizes to the acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in autosomal dominant  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
e47 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31819 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31820 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH chrna4b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal dominant nocturnal frontal lobe epilepsy 1 Epilepsy, nocturnal frontal lobe, 1 600513
    {Nicotine addiction, susceptibility to} 188890
    DISEASE ASSOCIATED WITH chrna4b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to nicotine (more)
    Cellular Component acetylcholine-gated channel complex (more)
    Molecular Function CONTRIBUTES_TO   acetylcholine receptor activity (more)
    GO Terms (all 24)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA chrna4b-201 (1) 2265
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chrna4b No data available
    MARKER RELATIONSHIPS
    chrna4b Contained in: [BAC] CH211-214D11 (1) (order this)
    chrna4b Encodes: [cDNA] MGC:198272 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001048063 (1) 2264 bp
    Genomic GenBank:CR762408 (1) 195238 bp
    Select Tool
    Polypeptide UniProtKB:Q0PJT8 (1) 627 aa
    Sequence Clusters UniGene:103932 (1)
    Sequence Information (all 12)
    ORTHOLOGY for chrna4b ( Chr: 11 )
    CITATIONS (28)