ZFIN ID: ZDB-GENE-040108-2
Gene Name: cholinergic receptor, nicotinic, alpha 2a (neuronal)
Gene Symbol: chrna2a
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: chrna2 (1), zgc:136717

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 4 publications
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa28784 Point Mutation Unknown Premature Stop ENU
sa36297 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from Menelaou et al., 2014
    Observed in:
    DISEASE ASSOCIATED WITH chrna2a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal dominant nocturnal frontal lobe epilepsy 4 Epilepsy, nocturnal frontal lobe, type 4 610353
    DISEASE ASSOCIATED WITH chrna2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process behavioral response to nicotine (more)
    Cellular Component acetylcholine-gated channel complex (more)
    Molecular Function CONTRIBUTES_TO acetylcholine receptor activity (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002394 (1)
  • InterPro:IPR006029 (1)
  • InterPro:IPR006201 (1)
  • InterPro:IPR006202 (1)
  • InterPro:IPR018000 (1)
  • InterPro:IPR036719 (1)
  • InterPro:IPR036734 (1)
  • PROSITE:PS00236 (1)
  • Pfam:PF02931 (1)
  • Pfam:PF02932 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA chrna2a-001 (1) 2368
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM chrna2a No data available
    MARKER RELATIONSHIPS
    chrna2aContained in: [BAC] CH73-51D8 (1) (order this), CH73-339L24 (1) (order this)
    chrna2aContains: [STS] chunp40142 (1)
    chrna2aEncodes: [cDNA] MGC:136717 (1) (order this), MGC:193799 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001040327 (1) 2390bp
    Genomic GenBank:CU571076 (1) 100888bp
    Select Tool
    Polypeptide UniProtKB:B3DGY1 (1) 520aa
    Sequence Clusters UniGene:134391 (1)
    Sequence Information (all 20)
    OTHER chrna2a GENE PAGES
  • Alliance (1)
  • Gene:678575 (1)
  • VEGA:OTTDARG00000034971 (1)
  • Ensembl(GRCz11):ENSDARG00000006602 (1)
  • ORTHOLOGY for chrna2a (Chr: 17)
    CITATIONS (26)